Pain hypersensitivity
Pain hypersensitivity in juvenile idiopathic arthritis: a quantitative sensory testing study
... mild pain and mild impair- ment or disability, as a group, they showed measurable abnormalities in sensory processing compared to healthy ...and Pain Clinics have greater degrees of pain and ...
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COX2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice
... is pain. The most common way of managing inflammatory pain is to use nonsteroidal antiinflammatory agents (NSAIDs) that reduce prostanoid production, for example, selective inhibitors of ...to pain ...
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Active immunization with myelin-derived altered peptide ligand reduces mechanical pain hypersensitivity following peripheral nerve injury
... treated animals. Indeed, macrophage depletion has been shown to attenuate pain hypersensitivity in some neuro- pathic pain models [34,36]. Recently however, the con- cept of formation of definitive ...
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The course of pain hypersensitivity according to painDETECT in patients with rheumatoid arthritis initiating treatment: results from the prospective FRAME cohort study
... inflammatory pain can lead to pain hypersensitivity of a reversible ...unclear pain mechanism indicating irreversible pain ...VAS pain 4 months after initiation or escalation of ...
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Pain Hypersensitivity: A Bio Psychological Explanation of Chronic Musculoskeletal Pain and Underpinning Theory
... The Gate Control Theory GCT can explanation pain hypersensitivity and it may assist us to understand a mechanism of chronic musculoskeletal pain.. In 1965, Melzack and Wall proposed that[r] ...
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<p>Development and preliminary evaluation of a short self-report measure of generalized pain hypersensitivity</p>
... The item-selection algorithm consistently yielded a single scale in which all seven items were included when lower- bound values for the H i coefficient of up to < 0.6 were used, supporting the unidimensionality of ...
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Generalized Mechanical Nerve Pain Hypersensitivity in Children With Episodic Tension-type Headache
... Fifty-two consecutive children who presented with headache between September and December 2009 were screened for eligibility criteria. Twenty-two (42%) children were ex- cluded: migraine (n ⫽ 7), hemicranial headache (n ...
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Pro-resolving mediator maresin 1 ameliorates pain hypersensitivity in a rat spinal nerve ligation model of neuropathic pain
... First, we examined whether MaR1 could attenuate mechani- cal allodynia and thermal hyperalgesia induced by SNL. There was a dramatic decrease of ipsilateral MWT and PWL from day 1, and the measurements reached the lowest ...
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Ca2+ binding protein NECAB2 facilitates inflammatory pain hypersensitivity
... inflammatory pain and heat hypersensitivity (45, 80, ...persistent pain, with BDNF modulating postsynaptic receptor accessibility and/or hypersensitivity ...
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Analysis of deep tissue hypersensitivity to pressure pain in professional pianists with insidious mechanical neck pain
... neck pain exhibit lower PPT levels over non-symp- tomatic points and normal over symptomatic ...pressure pain hypersensitivity in distant pain-free areas indicates sensitization of the central ...
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NFκB-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice
... obvious pain hypersensitivity, which was characterized by heat hyperalgesia (increased response to a noxious heat stimulus) and mechanical allodynia (painful response to a normally innocuous mechanical ...
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Lipoxin A4 inhibits microglial activation and reduces neuroinflammation and neuropathic pain after spinal cord hemisection
... and pain hypersensitivity, including mechanical hyperalgesia ...pro-inflammatory pain mediator because it can influence multiple mechanisms involved in pain ...pre-synaptic pain ...
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Spinal analgesic interaction between non steroidal anti inflammatory drugs and N methyl D aspartate receptor systems : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand
... administration of NMDA antagonists and non-steroidal anti-inflammatory drugs NSAI Ds, which inhibit COX enzymes reduce pain hypersensitivity Malmberg and Yaksh, 1 992; Dirig et al., 1 99[r] ...
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Original Article Inhibition of GAP-43 by propentofylline in a rat model of neuropathic pain
... Abstract: Neural plasticity within the spinal nociceptive network may be fundamental to the chronic nature of neuro- pathic pain. The relation of growth-associated protein-43 (GAP-43), a protein involved in the ...
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Minimizing the source of nociception and its concurrent effect on sensory hypersensitivity: An exploratory study in chronic whiplash patients
... spine pain intensity, the patients with chronic WAD demonstrated significant changes in measures indicative of sensory ...sensory hypersensitivity may be modulated by minimizing a potential peripheral ...
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Fruit-Induced FPIES Masquerading as Hereditary Fructose Intolerance
... symptoms have been reported. Al- though it may be disregarded for HFI, the reported case fi ts perfectly with the diagnostic criteria for FPIES, a non – IgE-mediated gastrointestinal food hypersensitivity ...
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Pain during ice water test distinguishes clinical bladder hypersensitivity from overactivity disorders
... group, Pain score was also recorded on a Visual Analogue Scale (VAS) for worst, least and average pain during the last 24 hours before the study [12] on a scale of 0 to 10 (0 – No Pain to 10 – ...
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Approach to the diagnosis of drug hypersensitivity reactions: similarities and differences between Europe and North America
... Iodinated contrast media, gadolinium chelates and dyes The USpp [9] does not consider STs a useful tool in evaluating hypersensitivity reactions to ICM, argu- ing that such reactions are non-IgE mediated with rare ...
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Beyond the Relief of Pain: Dentin Hypersensitivity and Oral Health-Related Quality of Life
... of Pain (IASP) [5]. However, compared to other body parts, pain perception from oral conditions, including DH, is considerable relative to the actual cause of the pain ...associated pain as ...
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Paclitaxel-activated astrocytes produce mechanical allodynia in mice by releasing tumor necrosis factor-α and stromal-derived cell factor 1
... chronic pain in various preclinical conditions including in animal models of chemotherapy- induced neuropathic ...chemotherapy-induced pain [16, 51, 52], astrocytes can be rapidly activated in the apparent ...
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