Pancreatic acinar cells
Enhanced proliferation of pancreatic acinar cells in MRL/ MpJ mice is driven by severe acinar injury but independent of infammation
... Adult pancreatic acinar cells have the ability to re-enter the cell cycle and proliferate upon injury or tissue ...of acinar proliferation is often limited and unable to completely regenerate ...
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Action of cholecystokinin and cholinergic agents on calcium transport in isolated pancreatic acinar cells
... The cholinergic antagonist atropine 10O M did not alter basal calcium outflux in isolated pancreatic acinar cells or the stimulation of calcium outflux produced by CCK-octapeptide, but a[r] ...
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Spatial aspects of Ca2+ signalling in pancreatic acinar cells
... Kasai and Augustine (1990) proposed a model that depends on fluctuating membrane potential to provide a unidirectional flow of Cl 2 through the cell. In this model, the cell at rest is more hyperpolarized than the Cl 2 ...
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Adaptive respiratory response of rat pancreatic acinar cells to mitochondrial membrane depolarization
... or pancreatic islets ...rat pancreatic acinar cells: FCCP had a much lower effect on respiration when only glucose was present [10] than in case of glutamine supplementation ...in ...
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Lycopene inhibits IL-6 expression in cerulein-stimulated pancreatic acinar cells
... in pancreatic acinar ...in pancreatic acinar ...in pancreatic acinar cells by determining the oxi- dant-mediated inflammatory signaling pathways ...
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Involvement of ryanodine operated channels in tert butylhydroperoxide evoked Ca2+ mobilisation in pancreatic acinar cells
... rat pancreatic acinar cells A suspension of single cells and small acini was obtained from isolate rat pancreas as described previously (Martínez et ...suspension. Acinar cells ...
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Original Article Interleukin-1β induces autophagy by affecting calcium homeostasis and trypsinogen activation in pancreatic acinar cells
... 2APB, an antagonist of the InsP 3 receptor, inhibited increased expression of autophagy markers. Subsequent bio- chemical assays revealed that co-culture with IL-1β could induce the activation of trypsinogen to trypsin ...
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Physiological and pathological intracellular calcium release in human and murine pancreatic acinar cells
... rodent pancreatic acinar ...seven cells in separate experiments with 10 pM CCK-8, all obtained in the presence of atropine (1 M) and tetrodotoxin (100 ...
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Beneficial Effects of Pyridoxal Phosphate on Hydrogen Peroxide Induced Stress on Isolated Pancreatic Acinar Cells
... [19,20]. Pancreatic exocrine cells were expressed of insulin- producing β cells by expressing PDX1, NGN3, and MAFA Genes ...However, pancreatic acinar cells were convert into ...
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Cross talk between calcium and cAMP dependent intracellular signaling pathways Implications for synergistic secretion in T84 colonic epithelial cells and rat pancreatic acinar cells
... various cells with combinations of agents that increase either cAMP or cytosolic calcium can lead to synergistic ...epithelial cells and rat pancreatic acinar ...chambers. Acinar cell ...
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Preexisting pancreatic acinar cells contribute to acinar cell, but not islet β cell, regeneration
... that pancreatic acinar cells can serve as progenitors for pancreatic islets, a concept with substantial implications for therapeutic efforts to increase insulin-producing β cell mass in ...
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Coxsackievirus Infection Induces Autophagy-Like Vesicles and Megaphagosomes in Pancreatic Acinar Cells In Vivo
... virus-infected cells in vitro and that modulation of the auto- phagic pathway (using chemicals or small interfering RNA- mediated knockdown) to enhance or dampen autophagy re- sults in an increase and a decrease, ...
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Adult pancreatic acinar cells give rise to ducts but not endocrine cells in response to growth factor signaling
... cells for diabetic patients has sparked considerable interest in finding ways to develop increased numbers of cells either in vivo or in ... cells can replicate to increase cell mass (Dor et ...
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Action of cholecystokinin and cholinergic agents on membrane bound calcium in dispersed pancreatic acinar cells
... dispersed acinar cells prepared from guinea pig pancreas, cellular uptake of 45Ca was moderately rapid and reached a steady state by 60 ...In acinar cells preloaded with 45Ca and then ...
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BENEFICIAL EFFECTS OF PYRIDOXAL PHOSPHATE ON HYDROGEN PEROXIDE INDUCED STRESS ON ISOLATED PANCREATIC ACINAR CELLS
... PLP is an active form of vitamin B6, well known for its anti-oxidant activity. The published work from our group was demonstrated cytoprotective and insulinotrophic effects of PLP against STZ induced beta cell ...
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In vitro action of bombesin on amylase secretion, membrane potential, and membrane resistance in rat and mouse pancreatic acinar cells A comparison with other secretagogues
... mouse pancreatic acinar cell membrane, reduction of membrane resistance, and a steep rise in amylase output from superfused pancreatic ...of acinar cells within an acinus, ...the ...
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The ATP2C2 Gene as Transcribed from a Novel Transcriptional Start Site in Pancreatic Acinar Cells
... HEK293A cells. It is curious that this promoter was active in HEK293A cells, which would not be expected to express a pancreas specific ...HEK293A cells did not show increased activity in response to ...
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Distribution and dynamics of endoplasmic reticulum-plasma membrane junctions in pancreatic acinar and pancreatic cancer cells
... muscle cells (Porter & Palade, ...these cells was quickly followed by identification of junctions in several other cell types (Engstrom, 1958; Fawcett & Revel, 1961; Reger, 1961; Rosenbluth, 1962; ...
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Pancreatitis in dogs and cats
... of pancreatic tissue by digestive enzymes that are prematurely activated within the pancreatic acinar ...Normally, pancreatic digestive enzymes are released from the pancreas as inactive ...
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The BRG1/SOX9 axis is critical for acinar cell–derived pancreatic tumorigenesis
... in pancreatic tumorigenesis and showed that the pancreas- specific loss of Brg1 in the presence of oncogenic Kras results in the formation of cystic neoplastic lesions that resemble human IPMN capable of ...
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