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pancreatic cancer

German National Case Collection for familial pancreatic Cancer (FaPaCa) - acceptance and psychological aspects of a pancreatic cancer screening program

German National Case Collection for familial pancreatic Cancer (FaPaCa) - acceptance and psychological aspects of a pancreatic cancer screening program

... familial Pancreatic Cancer (FaPaCa) was established in 1999 to prospectively collect FPC families [9, ...all cancer diagnoses in the family by re- view of medical and pathological records, death ...

9

Chemotherapy and tumor microenvironment of pancreatic cancer

Chemotherapy and tumor microenvironment of pancreatic cancer

... activation has been currently contentious and confusing. In 1990s, differential effects of IL-4 or IL-13 compared to IFN-γ and/or lipopolysaccharide (LPS) on macrophage gene expression were described. The macrophages ...

17

Erlotinib in the treatment of advanced pancreatic cancer

Erlotinib in the treatment of advanced pancreatic cancer

... metastatic pancreatic cancer after failure of front line therapy with gemcitabine (Blaszkowsky et al ...advanced pancreatic cancer to treatment arms consisting of bevacizumab (B) and ...

14

EGFR and HER2 inhibition in pancreatic cancer

EGFR and HER2 inhibition in pancreatic cancer

... mutated pancreatic cancer cell lines which displayed resistance to ...in pancreatic cancer tumours, and to identify a subset of patient most likely to benefit from lapatinib, expression of ...

9

LncRNAs in pancreatic cancer

LncRNAs in pancreatic cancer

... Panc-1 pancreatic cancer cell proliferation and survival through AURKA is more complex than we ...liver cancer cells, HOXA13 is not the downstream target of HOTTIP, but other HOX genes, such as ...

12

Advances in early detection of pancreatic cancer

Advances in early detection of pancreatic cancer

... of pancreatic ductal adenocarcinoma (PDAC) requires further examination after selecting cases with risk factors for the condition, such as family history, hereditary pancreatic carcinoma syndrome, ...

10

Harmine suppresses the proliferation of pancreatic cancer cells and sensitizes pancreatic cancer to gemcitabine treatment

<p>Harmine suppresses the proliferation of pancreatic cancer cells and sensitizes pancreatic cancer to gemcitabine treatment</p>

... of pancreatic cancer cells treated with harmine plus gemci- tabine were detached from the culture dishes, whereas the remaining adherent cells showed loss of adhesion, shrink- age, and rounding, which are ...

9

Therapeutics Progression in Pancreatic Cancer and Cancer Stem Cells

Therapeutics Progression in Pancreatic Cancer and Cancer Stem Cells

... Pancreatic cancer (PC) has one of the worst prognoses of any major malignancy ...of cancer death yearly in the United States and seventh cancer death in China [1] ...Nation Cancer ...

9

Evaluation of UHRF1 expression in pancreatic cancer

Evaluation of UHRF1 expression in pancreatic cancer

... Pancreatic cancer is highly resistant to chemotherapy [20] and several clinical trials are ongoing to improve its treatment ...for pancreatic cancer drugs, due to its multiple effects on ...

178

Alcohol intake and pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium (PanScan)

Alcohol intake and pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium (PanScan)

... Heterogeneity in the risk estimates for our study was assessed using the Q statistic and the I 2 statistic. We considered statistically significant heterogeneity at the P = 0.05 level of association. I 2 was used because ...

21

Refinement of screening for familial pancreatic cancer

Refinement of screening for familial pancreatic cancer

... imaging, 2 year screening intervals are suf fi cient and safe. Therefore, we now consider extending the screening intervals to 24 months in IAR with an unremarkable pancreas at baseline screening. This approach is also ...

9

The impact of cancer-associated fibroblasts on major hallmarks of pancreatic cancer

The impact of cancer-associated fibroblasts on major hallmarks of pancreatic cancer

... inflammatory cancer associated fibroblasts; IFP: interstitial fluid pressure; IGF-1: insulin-like growth factor 1; IL-6: interleukin 6; IL-8: interleukin 8; IL-1β: interleukin 1β; IL-1R1: interleukin-1 receptor 1; ...

16

SF3A1 and pancreatic cancer: new evidence for the association of the spliceosome and cancer

SF3A1 and pancreatic cancer: new evidence for the association of the spliceosome and cancer

... A two-stage case-control study was conducted to examine the association between six candidate U2-depedent spliceosome genes (SRSF1, SRSF2, SF3A1, SF3B1, SF1 and PRPF40B) and pancreatic cancer (PC). Subjects ...

8

Factors influencing receptivity to future screening options for pancreatic cancer in those with and without pancreatic cancer family history

Factors influencing receptivity to future screening options for pancreatic cancer in those with and without pancreatic cancer family history

... Pancreatic cancer worry and concern was assessed by four items adapted from Lerman and colleagues ...getting pancreatic cancer?” “How often have thoughts about your chances of getting pan- ...

9

Improving and Standardization in Diagnosis of Pancreatic Cancer

Improving and Standardization in Diagnosis of Pancreatic Cancer

... colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue ...in pancreatic cancer-derived cells inhibits in vitro cell proliferation but fails to alter tumor ...

7

Pancreatic cancer microenvironment: a current dilemma

Pancreatic cancer microenvironment: a current dilemma

... Pancreatic cancer is one of the leading causes of cancer-related death in the United States and survival outcomes remain dismal despite significant advances in molecular diagnostics and therapeutics ...

8

Common variables in European pancreatic cancer registries: The introduction of the EURECCA pancreatic cancer project

Common variables in European pancreatic cancer registries: The introduction of the EURECCA pancreatic cancer project

... elderly pancreatic cancer patients can be ...advanced pancreatic cancer patients, as well as metastasized patients are often directed to the medical ...

6

The role of palladin in pancreatic cancer

The role of palladin in pancreatic cancer

... In pancreatic cancer, this microenvironment has an excess of fibroblasts and extracellular matrix, and is known as ...of pancreatic cancer, as its presence signals a more aggressive and ...

89

Diet and pancreatic cancer

Diet and pancreatic cancer

... www.pancreaticcancer.org.uk/diet Pancreatic Cancer UK makes every effort to make sure that its services provide up-to-date, unbiased and accurate information about pancreatic ...

56

Pancreatic Cancer Genetics

Pancreatic Cancer Genetics

... of pancreatic development and function, including cholesterol synthesis, bile acid homeostasis, steroidogenesis and in regulating stem- ness ...of pancreatic acinar to ductal metaplasia (ADM) and impaired ...

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