Pancreatic Tumors
Transcriptional dissection of pancreatic tumors engrafted in mice
... metastatic tumors compared with primary ...metastatic tumors derived from the original primary tumors ...primary pancreatic tumors and pancreatic me- tastases located in ...
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Intraductal Delivery of Adenoviruses Targets Pancreatic Tumors in Transgenic Ela-myc Mice and Orthotopic Xenografts
... target pancreatic tumors by the retrograde delivery of adenoviruses into the common bile ...of pancreatic tumorogenesis and in pancreatic orthotopic ...acinar-ductal tumors in a ductal ...
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Renal tumors and second primary pancreatic tumors: a relationship with clinical impact?
... malignant tumors is expected to increase as the popula- tion ages ...and pancreatic tumors as an incidental finding [2]. These tumors are typically smaller than those that produce symptoms and ...
6
The estimation of metaloproteinases and their inhibitors blood levels in patients with pancreatic tumors
... Pancreatic cancer, its diagnostics, and therapy are the sub- ject of many meta-analyses [16-18]. The dynamics of solid tumor growth often results in a late diagnosis, which, con- sequently, hampers the radical ...
8
Surgical strategies for treatment of malignant pancreatic tumors: extended, standard or local surgery?
... related pancreatic surgery has progressed significantly during recent ...small pancreatic metastases located in the mid-portion of pancreas, central pancreatectomy (CP) is emerging as a safe and effective ...
10
Expansion of tumor-infiltrating lymphocytes (TIL) from human pancreatic tumors
... shared pancreatic cancer antigens can be elicited, and our results confirm that TIL expanded from pancreatic tumors are functional when re-stimulated with HLA-matched tumor targets [7, 13, ...from ...
12
Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302
... Background: Hypoxic niches in solid tumors harbor therapy-resistant cells. Hypoxia-activated prodrugs (HAPs) have been designed to overcome this resistance and, to date, have begun to show clinical efficacy. ...
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Three synchronous, sporadic and separate periampullary and pancreatic tumors: more than a coincidence?
... An 81-year-old male who presented with jaundice was found to have an ampullary cancer and an incidental pancreatic adenocarcinoma and a neuroendocrine cystic lesion. After stenting of the bile duct and medical ...
5
Simultaneous targeting of 5-LOX-COX and EGFR blocks progression of pancreatic ductal adenocarcinoma
... undifferentiated pancreatic carcinomas suggests that COX-2 and EGFR might represent targets for adjuvant therapy in anaplastic pancreatic cancer ...human pancreatic cancers ...underlying ...
16
Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP -positive cells
... from pancreatic tumors of LSL- MYCN;hGFAP-Cre ...regressing tumors induced by ...solid tumors including neuroblastoma [7] and JQ1- treated experimental medulloblastoma ...MYCN-dependent ...
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Axl-mediated activation of TBK1 drives epithelial plasticity in pancreatic cancer
... Although the majority of RAS effector–targeted therapies are focused on the RAF and PI3K signaling networks, there is considerable evidence supporting the less studied RALGEF/RAL effector pathway as a critical ...
15
The Challenging Diagnosis of Pancreatic Masses: Not All Tumors Are Cancers
... of pancreatic masses is usually considered sufficient for the diagnosis of pancreatic cancer and therefore only palliative and supportive care is ...all pancreatic tumors are ...untreatable ...
5
Sunitinib for the treatment of benign and malignant neoplasms from von Hippel-Lindau disease: A single-arm, prospective phase II clinical study from the PREDIR group
... bilateral tumors not accessible to conservative surgery or tumors that had recurred after surgery and/or radiofrequency ablation, or advanced/metastatic RCC; inextirpable or advanced neuroendocrine ...
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Original Article Study on clinical target volume (CTV) of pancreatic cancer: under the scope of CT scanning and pathology
... resected pancreatic cancer primary tumors were placed into the tissue fixa- tive liquid (formalin 10%) for 24 ...primary tumors and the anatom- ical relationship with the resected normal tis- sues at ...
8
Original Article Solid pseudopapillary neoplasm of the pancreas in children: a clinical and pathological study of 16 cases
... other solid tumors [45]. The characteristic cytoplasmatic paranuclear “dot-like” pattern described in SPNP had also been found in colonic adenomas/adenocarcinomas, pituicy- tomas and endometrial serous carcinomas ...
10
Solid Pseudopapillary Neoplasms of the Pancreas: A Report of Two Cases
... all pancreatic neoplasms. These tumors are being detected at an increased rate, probably due to the increased awareness and the liberal use of ...pseudopapillary pancreatic tumors and review ...
6
Prognostic Factors and Characteristics of Pancreatic Neuroendocrine Tumors: Single Center Experience
... As of March 2010, 9 patients (24.3%) showed disease pro- gression. The cumulative progression free survival was 89.2% at 1 year and 81.1% at 2 years. Median progression free sur- vival could not be calculated because ...
8
Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer
... [31], pancreatic cancer [10], breast cancer [9], melanoma [22, 32] and lung cancer ...i.e. pancreatic, breast, prostate, colon, brain, skin, and lung tumors [1, 3, 4, 7, ...
11
5672.pdf
... to pancreatic cancer tumorigenic properties through the regulation of an EGFR-Vav-Rac-PAK1-cyclinD1 pathway ...impaired pancreatic tumor growth in vitro and in ...Vav1-driven pancreatic cancer ...
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Neutrophil-Derived Proteases in the Microenvironment of Pancreatic Cancer -Active Players in Tumor Progression
... granules. Several proteases, in particular MMPs, were described to be upregulated in different cell types in malignant tissues thus showing an enhanced capabil- ity to digest various proteins of the extracellular ma- ...
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