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Papillary renal cell carcinomas

Original Article Decreased expression of receptor tyrosine kinase of EphB1 protein in renal cell carcinomas

Original Article Decreased expression of receptor tyrosine kinase of EphB1 protein in renal cell carcinomas

... [6] Albiges L, Guegan J, Le Formal A, Verkarre V, Rioux-Leclercq N, Sibony M, Bernhard JC, Camparo P, Merabet Z, Molinie V, Allory Y, Orear C, Couve S, Gad S, Patard JJ and Escudier B. MET is a potential target across ...

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A Case of Reed Syndrome with a Novel Mutation in the Fumarate Hydratase Gene

A Case of Reed Syndrome with a Novel Mutation in the Fumarate Hydratase Gene

... Reed syndrome is a rare hereditary cancer predisposition syndrome associated with multiple cutaneous and uterine leiomyomas and type 2 papillary renal cell carcinomas (pRCC) as well as ...

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Original Article Stability of preclinical models of aggressive renal cell carcinomas

Original Article Stability of preclinical models of aggressive renal cell carcinomas

... pathological data for the six human RCC and the corresponding xenografts in mice at P1 and P5 are given in Table 1. The median age of the 6 patients was 64 and all patients already had distant metastases at time of ...

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Dysregulation of Met receptor tyrosine kinase activity in invasive tumors

Dysregulation of Met receptor tyrosine kinase activity in invasive tumors

... human renal papillary carcinomas) elevates c-Src phosphorylation and activity — an effect that is considerably more dramatic and longer-lasting than the transient activation of c-Src by HGF in normal ...

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Piwi-interacting RNAs as novel prognostic markers in clear cell renal cell carcinomas

Piwi-interacting RNAs as novel prognostic markers in clear cell renal cell carcinomas

... by papillary RCC at 6 – 15 % and chro- mophobe RCC at 2–5 ...from papillary or chromophobe RCC [3, ...with papillary RCC type 1 have a more favorable outcome than those with type 2 ...of ...

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Original Article EphA4 protein promotes invasion in clear cell renal cell carcinomas

Original Article EphA4 protein promotes invasion in clear cell renal cell carcinomas

... Clear cell renal cell carcinoma (ccRCC) is the most prevalent cancer of the kidney, account- ing for approximately 75% of renal cell carcino- ma (RCC) [1, ...common renal ...

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Xp11.2 translocation renal cell carcinomas in young adults

Xp11.2 translocation renal cell carcinomas in young adults

... Of the 879 consecutive adult RCCs in our institution from 2008 to 2013, 103 patients were in the age range of 18–45 years. Five cases without complete clinical data were excluded. Of the remaining 98 patients, there were ...

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Retroperitoneal teratoma with somatic malignant transformation: A papillary renal cell carcinoma in a testicular germ cell tumour metastasis following platinum-based chemotherapy

Retroperitoneal teratoma with somatic malignant transformation: A papillary renal cell carcinoma in a testicular germ cell tumour metastasis following platinum-based chemotherapy

... of papillary renal cell cancer. Papillary renal cell cancer is differentiated from other subtypes of renal cell cancer by using CK7 and AMACR immunohistochemical ...

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Original Article Expression of EphA2 protein is positively associated with age, tumor size and Fuhrman nuclear grade in clear cell renal cell carcinomas

Original Article Expression of EphA2 protein is positively associated with age, tumor size and Fuhrman nuclear grade in clear cell renal cell carcinomas

... in renal cell carcinoma has been studied to a degree by several groups and summarized in Table ...in renal cell carcinoma cell lines and 40 patients with ...3 papillary, and 1 ...

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Case Report Synchronous renal neoplasms: clear cell renal cell carcinoma, papillary renal cell carcinoma, and multilocular cystic renal cell neoplasm of low malignant potential in the same kidney

Case Report Synchronous renal neoplasms: clear cell renal cell carcinoma, papillary renal cell carcinoma, and multilocular cystic renal cell neoplasm of low malignant potential in the same kidney

... malignant carcinomas have been reported in many organs with a poor prognosis which were characterized by the coexistence of two or more histologically different malignant neoplasms ...synchronous renal ...

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Identification of Metastamirs as Metastasis-associated MicroRNAs in Clear Cell Renal Cell Carcinomas

Identification of Metastamirs as Metastasis-associated MicroRNAs in Clear Cell Renal Cell Carcinomas

... As described, a stepwise down-regulation of miRNA expression from normal over primary tumor to metastatic tissue samples appears to be more typi- cal than an up-regulated expression in RCC progres- sion. Already in 2005 ...

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Review Article Clear cell papillary renal cell carcinoma: a review

Review Article Clear cell papillary renal cell carcinoma: a review

... clear cell RCC, papillary RCC, ...clear cell RCCs show focal or extensive papillary architecture [31- ...clear cell RCC with ...clear cell RCC [23, 34]. On rare occasions, CK 7 ...

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Somatic mutations in renal cell carcinomas from Chinese patients revealed by whole exome sequencing

Somatic mutations in renal cell carcinomas from Chinese patients revealed by whole exome sequencing

... which participates in the transcription of some genes regulating metabolism and angiogenesis [17, 18]. Hence, the absence of pVHL function can result in the accu- mulation of HIF, which can contribute to the dysregula- ...

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Case Report Alveolar soft-part sarcoma of the prostate: a case report and review of the literature

Case Report Alveolar soft-part sarcoma of the prostate: a case report and review of the literature

... Gross examination shows that ASPS is gener- ally nodular. The tumor may have a false cap- sule and poor border, ranging in size from 1 to 24 cm. ASPS tends to be gray brown in color and have a soft, flesh texture. Larger ...

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The Gene Master Regulators (GMR) Approach Provides Legitimate Targets for Personalized, Time-Sensitive Cancer Gene Therapy

The Gene Master Regulators (GMR) Approach Provides Legitimate Targets for Personalized, Time-Sensitive Cancer Gene Therapy

... tissue in a case of metastatic clear cell renal cell carcinoma, a case of papillary thyroid cancer and two 356. cases of prostate cancer[r] ...

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Malignant Thyroid Lesions: A Histopathological Perspective

Malignant Thyroid Lesions: A Histopathological Perspective

... intensity with modern imaging leading to over diagnosis of small tumors [17,18,19,20]. This small tumors have been tagged “clinically unimportant” as they pose little or no immediate/long term risk to patient, but rather ...

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Positive/retained SDHB immunostaining in renal cell carcinomas associated to germline SDHB-deficiency: case report

Positive/retained SDHB immunostaining in renal cell carcinomas associated to germline SDHB-deficiency: case report

... According to the 2016 WHO classification, SDH-deficient RCC is composed of uniform cells characteristically display- ing eosinophilic granular material intermixed with fewer cells exhibiting clear intracytoplasmic ...

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PD-L1 expression in papillary renal cell carcinoma

PD-L1 expression in papillary renal cell carcinoma

... Renal cell carcinoma (RCC) is a common cancer of the kidney, and the three most frequent histological subtypes are clear cell RCC (ccRCC, 70 to 80%), papillary RCC (pRCCc, 10 to 20%), and ...

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Pathogenic mechanisms of deregulated microRNA expression in thyroid carcinomas of follicular origin

Pathogenic mechanisms of deregulated microRNA expression in thyroid carcinomas of follicular origin

... thyroid carcinomas cul- minating in TGFb-dependent EMT and elevated inva- siveness, as observed for ATCs ...stem cell factor and a powerful inducer of pluripotency ...

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High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas

High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas

... undifferentiated thyroid cancer are not known. We examined normal, benign, and malignant thyroid tissue for structural abnormalities of the p53 tumor suppressor gene. Mutations were detected by single-strand conformation ...

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