Parainfluenza Virus 3, Human
Respiratory virus associated with surgery in children patients
... respiratory virus infections in post-surgery mild symptomatic PSP group and asymptomatic PSP group using a quantitative real-time reverse transcriptase polymerase chain reaction (qRT-PCR) assay ...were ...
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Recombinant type 5 adenoviruses expressing bovine parainfluenza virus type 3 glycoproteins protect Sigmodon hispidus cotton rats from bovine parainfluenza virus type 3 infection.
... Human adenovirus type 5 is a suitable vector for expressing bPIV3 glycoproteins (23). F and HN proteins produced by recombinant adenoviruses either alone or in combination were sufficient to induce a protective ...
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Identification of Interferon-Stimulated Gene Proteins That Inhibit Human Parainfluenza Virus Type 3
... the human IFIT family regulate translation by differentially recognizing the 5= ter- mini of their target RNA (28, ...matitis virus (VSV), Newcastle Disease virus (NDV), and RSV, have been ...
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Chimeric Bovine/Human Parainfluenza Virus Type 3 Expressing Respiratory Syncytial Virus (RSV) F Glycoprotein: Effect of Insert Position on Expression, Replication, Immunogenicity, Stability, and Protection against RSV Infection
... the virus population expressing RSV F (Table ...of virus plaques; in the inoculum for F3, 20% of the virus plaques were extremely small and were not detected by RSV F ...
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A Chimeric Human-Bovine Parainfluenza Virus Type 3 Expressing Measles Virus Hemagglutinin Is Attenuated for Replication but Is Still Immunogenic in Rhesus Monkeys
... sles virus and protected the monkeys from challenge with biologically derived ...for virus titer. Virus titers are expressed as mean log 10 TCID 50 per milliliter ⫾ ...
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Rapid semi automated quantitative multiplex tandem PCR (MT PCR) assays for the differential diagnosis of influenza like illness
... syncytial virus (RSV) is the single most important cause of acute lower respiratory tract diseases including bronchiolitis and pneumonia in infants and young children and may contribute to hundreds of thou- sands ...
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Antigenic and structural properties of the hemagglutinin-neuraminidase glycoprotein of human parainfluenza virus type 3: sequence analysis of variants selected with monoclonal antibodies which inhibit infectivity, hemagglutination, and neuraminidase activities.
... 5 Antigenic and Structural Properties of the HemagglutininNeuraminidase Glycoprotein of Human Parainfluenza Virus Type 3: Sequence Analysis of Variants Selected with Monoclonal Antibodie[r] ...
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Enhanced Neutralizing Antibody Response Induced by Respiratory Syncytial Virus Prefusion F Protein Expressed by a Vaccine Candidate
... syncytial virus (RSV) and human parainfluenza virus type 3 (HPIV3) are the first and second leading viral agents of severe respiratory tract disease in infants and young children ...
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Expression of the Surface Glycoproteins of Human Parainfluenza Virus Type 3 by Bovine Parainfluenza Virus Type 3, a Novel Attenuated Virus Vaccine Vector
... for virus growth in vitro yet was attenuated in rhesus ...syncytial virus (RSV) was evaluated as a live, attenuated vaccine in chimpanzees, a host that is highly permissive for hRSV infection but does not ...
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Inflammasome Antagonism by Human Parainfluenza Virus Type 3 C Protein
... A role of the MeV V protein in blocking inflammasome activation was reported previously (69). The MeV V protein diminished NLRP3-driven IL-1  secretion from THP-1 macrophages (69). Following inflammasome activation by ...
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Involvement of Actin Microfilaments in the Replication of Human Parainfluenza Virus Type 3
... the virus contains a protein(s) that interacts directly or indirectly with ...the virus for its transcription/replication without having the pro- teins packaged within the ...
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The Second Receptor Binding Site of the Globular Head of the Newcastle Disease Virus Hemagglutinin-Neuraminidase Activates the Stalk of Multiple Paramyxovirus Receptor Binding Proteins To Trigger Fusion
... syncytial virus (RSV) and human metapneumovirus (hMPV), also possess a third, crit- ical function: they activate the F protein to mediate the merger of the viral envelope with the host cell ...measles ...
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A Leucine Residue in the C Terminus of Human Parainfluenza Virus Type 3 Matrix Protein Is Essential for Efficient Virus-Like Particle and Virion Release
... we took advantage of two well-characterized plasma membrane- targeting signals: L10, a peptide containing 10 aa derived from the N terminus of Lck, and S15, a peptide containing 15 aa derived from the N terminus of c-Src ...
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Mechanism of Interference Mediated by Human Parainfluenza Virus Type 3 Infection
... The biological significance of glycoprotein-mediated inter- ference for HPF3 and other paramyxoviruses remains to be determined. For retroviruses, superinfection exclusion could prevent multiple provirus insertions and ...
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Prevalence of Viral Severe Acute Respiratory Infections in Patients in the Intensive Care Unit and Those under Mechanical Ventilation in Moi Teaching and Referral Hospital, Uasin Gishu County, Kenya
... for Human Coronavirus in ICU and MV ...MV, 3% Rhinovirus in ICU and 1% Parainfluenza 1 in ICU, this is comparable with a study of 78 children less than five years with acute respiratory failure under ...
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Adaptation of Human Parainfluenza Virus to Airway Epithelium Reveals Fusion Properties Required for Growth in Host Tissue
... includes human parainfluenza virus type 3 (HPIV3), cause the majority of childhood croup, bronchiolitis, and pneumonia ...differentiated human airway epithelium (HAE) cultures and in ...
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Identification of a natural human serotype 3 parainfluenza virus
... Parainfluenza virus is an important pathogen threatening the health of animals and human, which brings human many kinds of disease, especially lower respiratory tract infection involving ...
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Proteins associated with human parainfluenza virus type 3.
... The viral origin of the polypeptides was further confirmed by immunoprecipitation of infected cell lysates with rabbit hyperimmune antisera against the envelope and core fractions of pur[r] ...
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An infectious clone of human parainfluenza virus type 3.
... Analysis of numerous mutations with the infectious clone will probably identify mutations which attenuate the virus. These mutations could be used to develop new vaccine strains of HPIV-3. Alternatively, ...
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Features of Circulating Parainfluenza Virus Required for Growth in Human Airway
... The proportions of individual single-nucleotide polymor- phisms (SNPs) in each open reading frame (ORF) of CI-13 are shown in Table 1. CI-13 was used for the SNP analysis to analyze the stability during passage in HAE ...
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