Parathyroid hormone 2 receptor
Model of the complex of Parathyroid hormone 2 receptor and Tuberoinfundibular peptide of 39 residues
... a hormone receptor, has an extracellular N-terminal domain (ECD), a trans- membrane (TM) domain and an intracellular C-terminal domain ...the hormone to the ECD and its interactions with the ...
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Integrated network analysis to explore the key genes regulated by parathyroid hormone receptor 1 in osteosarcoma
... metalloproteinase 2 ( MMP2 ), astrocyte elevated gene 1 ( AEG1 ) functions in OS progression can be used for predicting the progression and prognosis of the disease [5, ...
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The calcium sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone
... In vivo experiments. Animal protocols were approved by the institutional animal care and use committee at Har- vard Medical School and were in accordance with the NIH Guide for the Care and Use of Laboratory Animals. ...
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Expression of parathyroid hormone/parathyroid hormone-related peptide receptor 1 in normal and diseased bladder detrusor muscles: a clinico-pathological study
... termed low-compliance bladder, and is typically seen in paediatric cases with congenital spinal disorders, posterior urethral valves, and also in rare forms of severe non- neurogenic neurogenic bladder (Hinman syndrome). ...
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Activated parathyroid hormone/parathyroid hormone–related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone
... In bone remodeling the activities of osteoblasts, the bone-forming cells, and osteoclasts, cells of hematopoi- etic origin capable of resorbing bone, must be balanced carefully in order to maintain skeletal integrity ...
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Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats
... (20% 2-hydroxypropyl-β— cyclodextrin, per os), and three additional OVX groups that received either NPS 2143 (100 µmol/kg, per os); 17β-estradiol, administered as a continuous infusion using a subcutaneously ...
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The calcium-sensing receptor regulates parathyroid hormone gene expression in transfected HEK293 cells
... Over-expression of the CaR decreases PTH mRNA levels in co-transfected HEK293 cells. HEK293 cells were transiently co-transfected in triplicate with expression plasmids for the hPTH gene and control GFP or GH and either ...
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Behavioral and Neurochemical Assessment of Parathyroid Hormone 2 (PTH2) Receptor Agonist Tuberoinfundibular Peptide of 39 (TIP39) in Neurological Disorders
... depression, monoamine pathway is seen as the primary pathway embattled by most of the currently available depression therapies [5]. HPA axis hypothesis, which acts as a central part in mediating the responses to various ...
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ANAESTHETIC MANAGEMENT OF PRIMARY HYPERPARATHYROIDISM WITH RARE PRESENTATION OF MULTIPLE BROWN’S TUMOUR
... to parathyroid hormone at the level of receptor in kidney (renal resistance) in long standing cases of hyperparathyroidism and CRF with resultant autonomous function of ...HPT 2 and extremely ...
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Altered expression of inflammatory cytokines in primary osteoarthritis by human T lymphotropic virus type I retrovirus infection: a cross sectional study
... terminal parathyroid hormone-related peptide (C-PTHrP), soluble interleukin-2 receptor (sIL-2R) and interleukin (IL)-6, and an osteo-destruction marker, deoxypyridinoline, in synovial fluid ...
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Absence of functional receptors for parathyroid hormone and parathyroid hormone related peptide in Blomstrand chondrodysplasia
... PTH/PTHrP receptor, in addition to its role in regulating mineral metabolism, also plays an essential role in fetal devel- opment due to the important regulatory effects of PTHrP on the development of cartilage ...
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CORRELATION OF PARATHYROID HORMONE-1 RECEPTOR EXPRESSION TO BONE METASTASIS OF BREAST CARCINOMA PATIENTS
... The Parathyroid Hormone-related Peptide (PTHrP) is a protein which has an important role in breast cancer cells to invade and infiltrate bones or bone marrow and accelerate angiogenetic ...PTHrP ...
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Vitamin D3 differentially regulates parathyroid hormone/parathyroid hormone related peptide receptor expression in bone and cartilage
... lyl nucleotide–binding (G) protein-coupled receptor (PTHR) (32). The PTHR is widely expressed, with the highest levels being found in kidney and bone (33). The mouse gene encoding the PTHR is composed of at least ...
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Seizures as the first manifestation of chromosome 22q11 2 deletion syndrome in a 40 year old man: a case report
... the parathyroid glands during ...the parathyroid glandular dysfunction ranges from hypocalcemia with hypoparathyroidism to normo- calcemia with normal parathryroid hormone levels ...
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A Histological Study of Surgically Resected Appendices in Clinically Suspected Appendicitis with Special Reference to Eosinophils and Mast Cells
... the parathyroid glands during thyroid surgery can lead to transient or permanent ...to parathyroid glands during thyroid ...intraoperative parathyroid hormone levels (ioPTH) to predict the ...
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Case report: lady with bone pains for 5 years—parathyroid carcinoma
... as high (155 mg/day) as expected in association with these levels of PTH [9–11], given a reasonably sufficient (840 mL) 24 h urine collection. The relatively low 24 h urine calcium could in part be explained by the ...
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Effect of parathyroid hormone on erythropoiesis
... Inhibitors of erythropoiesis have been found in the blood of uremic patients but their nature has not been identified. These patients have excess blood levels of parathyroid hormone (PTH) and it is possible ...
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Parathyroid hormone like protein is a secretory product of atrial myocytes
... Transforming growth factor-#, Stimulation of parathyroid hormone-related protein expression in human uterine cells in culture: mRNA and protein secretion.. Stretchinduced parathyroid hor[r] ...
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Parathyroid Hormone in Human Plasma: IMMUNOCHEMICAL CHARACTERIZATION AND BIOLOGICAL IMPLICATIONS
... anti-bovine parathyroid hormone antisera was characterized by their reactivity with bovine hormonal fragments (1-34, 1-13, 14-34, 19-34, 53-84) and human hormone extracted from parathyroid ...
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Parathyroid Ablation in Dystrophic Hamsters: EFFECTS ON CA CONTENT AND HISTOLOGY OF HEART, DIAPHRAGM, AND RECTUS FEMORIS
... Because parathyroid hormone (PTH) stimulates calcium influx into the cytosol, the chronic effects of surgical ablation of the parathyroid glands on muscle Ca, Mg, protein synthesis, and histology, as ...
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