PDGF, platelet-derived growth factor
Detection of platelet derived growth factor (PDGF) AA in actively healing human wounds treated with recombinant PDGF BB and absence of PDGF in chronic nonhealing wounds
... recombinant platelet-derived growth factor-BB (rPDGF-BB) show increased healing coupled with fibroblast activation and granulation tissue ...endogenous PDGF is associated with healing ...
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Structural optimization and evaluation of novel 2-pyrrolidone-fused (2-oxoindolin-3-ylidene)methylpyrrole derivatives as potential VEGFR-2/PDGFRβ inhibitors
... epidermal growth factor; FGF: fibroblast growth factor; VEGF: vascular endothelial growth factor; PDGF: platelet‑derived growth factor; RCC: ...
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Chrysotile asbestos upregulates gene expression and production of alpha receptors for platelet derived growth factor (PDGF AA) on rat lung fibroblasts
... mainly PDGF-R beta and a paucity of PDGF-R ...with PDGF-AA, which binds only PDGF-R alpha, blocked the PDGF binding sites that were upregulated by fiber ...exposure. PDGF-AA had ...
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<p>Treatment of recurrent myopic macular hole using membrane of plasma rich in growth factors</p>
... in growth factors (PRGF) is a novel autologous ophthalmic therapy that contains a large number of biologically active agents, including EGF (epider- mal growth factor), PDGF ...
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PDGF/PDGFR effects in osteosarcoma and the “add-on” strategy
... The platelet-derived growth factor (PDGF)/platelet-derived growth factor receptor (PDGFR) pathway plays an important role in the development and metastasis ...
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Nintedanib: evidence for its therapeutic potential in idiopathic pulmonary fibrosis
... the platelet-derived growth factor (PDGF)/PDGF receptor pathway is thought to play a critical role in fibrogenesis of the ...Other growth factors, including fibroblast ...
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Platelet isoforms of platelet derived growth factor stimulate fibroblasts to contract collagen matrices
... of growth factors that are thought to initiate and sustain the ...the platelet and monocyte isoforms of platelet-derived growth factor (PDGF; AB and BB) but not ...
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Regional expression of the platelet derived growth factor and its receptors in a primate graft model of vessel wall assembly
... express PDGF mRNA in the ...contain PDGF-like mitogenic ...the PDGF protein isoforms and their receptors in this prosthetic graft ...both PDGF-A and PDGF-B were identified in ...
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Effects of platelet derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat storing cells
... of growth curves revealed a similar pattern of potency of the growth ...and PDGF. FSC showed high specific binding of 125I-PDGF and Scatchard analysis revealed high affinity receptors with an ...
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Original Article The overexpression of PDGF-BB and its receptor is correlated with lymphatic metastasis in patients with non-small cell lung cancer
... prognostic factor for human ...multiple growth factors. Platelet-derived growth factor-BB (PDGF-BB) and platelet-derived growth factor ...
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Platelet Rich Plasma Intra Articular Injection for Chronic Synovitis Treatment in Patients with Haemophilia One Year Follow Up
... [5]. Platelet-rich plasma (PRP) is used to stimulate healing of the joint and provide symptomatic relief ...with growth factors and proteins used in joint homeostasis, healing mechanisms and tissue ...
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Wound Treatment Using Growth Factors
... with growth factors is an effective method to promote wound ...Several growth factors have been used in wound treatment, including basic fibroblast growth factor (bFGF) discovered in the ...
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Platelet-derived growth factor regulates the secretion of extracellular vesicles by adipose mesenchymal stem cells and enhances their angiogenic potential
... activity. PDGF is known to play a key role in neovasculari- zation after injury ...Indeed, PDGF stimulated the secretion of ASC-EVs with de novo expression of pro-angiogenic molecules such as c-KIT and SCF, ...
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Induction of sustained expression of proto oncogene c fms by platelet derived growth factor, epidermal growth factor, and basic fibroblast growth factor, and its suppression by interferon gamma and macrophage colony stimulating factor in human aortic medial smooth muscle cells
... of platelet-derived growth factor (PDGF)-BB and either epidermal growth factor (EGF) or fibroblast growth factor (FGF) induced high expression of c-fms in ...
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Growth factor expression in aorta of normotensive and hypertensive rats
... of platelet-derived growth factor (PDGF) B chain and PDGF A chain, insulin-like growth factor (IGF)-I and IGF-II, endothelial cell growth factor ...
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Characterization of biologically active, platelet derived growth factor like molecules produced by murine erythroid cells in vitro and in vivo
... hematopoietic growth factors we demonstrated that PDGF-like biological activity was specifically immunoprecipitated by both monoclonal and polyclonal anti-human PDGF antibodies but not by antibodies ...
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Evaluation of effectiveness of concentrated growth factor on osseointegration
... many growth factors such as bone morphogenetic protein (BMP), platelet-derived growth factor (PDGF), insulin-like growth factor (IGF), vascular endothelial ...
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Platelet derived growth factor inhibits bone regeneration induced by osteogenin, a bone morphogenetic protein, in rat craniotomy defects
... Platelet-derived growth factor (PDGF) is a potent moderator of soft tissue repair through induction of the inflammatory phase of repair and subsequent enhanced collagen ...homodimer ...
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Safety study: is there a pathologic IGF-1, PDGF and TGF-ß cytokine expression caused by adjunct BMP-7 in tibial and femoral non-union therapy?
... like growth factor 1 (IGF-1), platelet-derived growth factor AB (PDGF-AB) and transforming growth factor beta (TGF-β) were compared between patients with the ...
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Expressions of Growth Factors in Autologous Derived Platelet-Rich Plasma and Platelet-Poor Plasma; Implication for Tissue Reparation and Wound Healing
... each factor. Any growth factor present was bound by the immobilized ...each growth factor was added to the ...bound growth factor in the first ...FGF-2, PDGF-AA and ...
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