Pemphigus foliaceus
Explanations for the clinical and microscopic localization of lesions in pemphigus foliaceus and vulgaris
... with pemphigus foliaceus (PF) have blisters on skin, but not mucous membranes, whereas patients with pemphigus vulgaris (PV) develop blisters on mucous membranes and/or ...of pemphigus IgG to ...
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Absence of Intercellular Antigens in the Deep Layers of the Epidermis in Pemphigus Foliaceus
... 12), pemphigus foliaceus patients had intercellular deposits of IgG localized solely or predominantly in the superficial epidermal layers, whereas this was not the case in any of the patients with ...
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Pemphigus foliaceus IgG causes dissociation of desmoglein 1–containing junctions without blocking desmoglein 1 transinteraction
... Autoantibodies against the epidermal desmosomal cadherins desmoglein 1 (Dsg1) and Dsg3 have been shown to cause severe to lethal skin blistering clinically defined as pemphigus foliaceus (PF) and ...
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Desmoglein 1–specific T lymphocytes from patients with endemic pemphigus foliaceus (fogo selvagem)
... of pemphigus foliaceus that has been reported in certain regions of Brazil since the beginning of this century ...of pemphigus foliaceus has also been described in certain parts of Colombia ...
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Identification of pemphigus vulgaris antigen extracted from normal human epidermis and comparison with pemphigus foliaceus antigen
... keratinocytes and epidermis have identical charges and sizes. In addition to precipitating the PV complex, 14 of 22 PV sera also have antibodies to a calcium-sensitive epitope on a different complex of polypeptides (PF ...
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Prediction of survival for patients with pemphigus vulgaris and pemphigus foliaceus: a retrospective cohort study
... Previous studies provided fragmented information suggesting that an older age of onset [3,10,11,13], concomitant involvement of the skin and mucosal surface at early disease presentation [9,14,15], delayed initiation of ...
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Identification of Desmocollin-1 as a Major Target Autoantigen in Canine Pemphigus Foliaceus.
... form of DSCs is due to the partial deletion of the catenin-binding domain in the cytoplasmic tail. 20 Plakoglobin has been shown to also interact with PKPs 14, 34 , E-cadherin and α - catenin, the latter two being part ...
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Distinction between epidermal antigens binding pemphigus vulgaris and pemphigus foliaceus autoantibodies
... To confirm that PF antibodies, which specifically bound to a 160,000-mol wt protein band on immunoblots, were actually pemphigus antibodies, we eluted the IgG from the protein that was c[r] ...
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Fipronil-amitraz-S-methoprene-triggered pemphigus foliaceus in 21 dogs: clinical, histological and immunological characteristics
... Little is known about the exact trigger leading to the antibody production and disease development in the PTPF and CTPF. Genetic background, immunological or hormonal status are all well-known factors that can influ- ...
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Monovalent Fab' immunoglobulin fragments from endemic pemphigus foliaceus autoantibodies reproduce the human disease in neonatal Balb/c mice
... This possibility is in agreement with our findings, which showed that mice injected with unfractionated FS IgG developed disease and exhibited murine C3 bound to the epidermal ICS, where[r] ...
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Evaluation the role of direct immunofluorescence techniques and their relevance to the diagnosis of the blistering diseases
... by pemphigus vulgaris n= 10 ...Then pemphigus foliaceus n=8 ...as pemphigus vegetans tow (25%)of them have negative immunofluorescence and in tow of them (25%)the diagnosis of paraneoplastic ...
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A REVIEW ON DESMOGLEINS, DESMOCOLLINS AND ASSOCIATED DISEASESMuhammad Javed Khan*, Imran Khan, Irshad Ali, Sheikh Ahmed, Ghulam Mustafa KhanDOWNLOAD/VIEW
... like pemphigus foliaceus and pemphigus vulgaris [56, ...in pemphigus foliaceus, which is expressed in all the epidermal layers is desmoglein 1 (a transmembrane glycoprotein) [58, ...in ...
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Direct Immunofluorescence in Immunobullous disorders of skin with histopathological correlation.
... dermatitis, pemphigus foliaceus, bullous pemphigoid, herpes gestationis, drug eruptions, spongiotic arthropod bite reactions, and transient acantholytic ...
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Chronic Paronychia and Onychomadesis in Pemphigus Vegetans: An Unusual Presentation in a Rare Autoimmune Disease
... of pemphigus vulgaris and pemphigus foliaceus with more than 97 percent of sensitivity and specificity, the data are still limited for Pveg ...nonclassical pemphigus (para- neoplastic ...
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Erythroderma: study of clinico etiology and complications from Western India
... The mean age of onset was 43.99 years with a male to female ratio of 2.1:1. The clinical lls, lymphadenopathy and edema. On clinicopathological correlation the most common aetiology found was psoriasis vulgaris, ...
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Prevalence of pemphigus and pemphigoid autoantibodies in the general population
... In contrast to the detection of other autoantibodies in healthy individuals, e.g., ANA [17], the potential patho- genic activity of anti-BP180-NC16A IgG and Dsg1/3 can be tested [6]. As shown here, anti-BP180-NC16A IgG ...
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A Clinicopathological study of Autoimmune Vesiculobullous Diseases
... with pemphigus vulgaris were seen in 13 patients, pemphigus foliaceus in 2 patients, pemphigus erythematosus in 3 patients, IgA pemphigus in one patient, bullous pemphigoid in 8 ...
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... 1:2. Pemphigus Vulgaris (PV), Pemphigus Vegetans, Pemphigus Foliaceus, Pemphigus Erythematous, Paraneoplastic Pemphigus (PNP) and drug related pemphigus are major variants ...
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... PV- Pemphigus vulgaris, PF – Pemphigus foliaceus, PE – Pemphigus erythematosus, BP- Bullous pemphigoid, EBA- Epidermolysis bullosa acquisita, DH- Dermatitis herpetiformis, SJS- Steven Johnson ...
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Study of HLA DR and DQ Types in Patients with Pemphigus Vulgaris as Compared to that in Healthy Subjects
... 38 pemphigus vulgaris patients did not correlate with the disease severity ...the pemphigus foliaceus patients the serum IgG 4 titres had a positive correlation with PDAI ...
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