Pentraxin-3
The inflammatory protein Pentraxin 3 in cardiovascular disease
... synoviocytes transcription of the PTX3 messenger RNA (mRNA) was found to be directly promoted by serum amyloid A [75]. Moreover, plasma analysis and gene ex- pression profile revealed that PTX3 might be involved in the ...
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Association between Pentraxin 3 and Cardiac Troponin I with Left Ventricular Systolic Function in Patients with Anterior ST Segment Elevation Myocardial Infarction: Evaluation by Speckle Tracking Echocardiography
... of pentraxin-3 in STE-ACS patients was reported by Latini and colleagues, who reported an association between serum pentraxin-3 and 3-months cardiac events after acute ...median ...
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Upregulation of brain-derived neurotrophic factor in advanced gastric cancer contributes to bone metastatic osteolysis by inducing long pentraxin 3
... The brain-derived neurotrophic factor (BDNF) activates its receptor, tropomyosin receptor kinase B (TrkB; also called NTRK2) that has been shown to promote the malignant progression of several cancers. In this study, we ...
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Study of Pentraxin-3 as an Early Marker of Diabetic Nephropathy in Type 2 Diabetes Mellitus
... [9] Mantovani, A., Garlanda, C., Doni, A. & Bottazzi, B. “Pentraxins in innate immunity: from C-reactive protein to the long pentraxin PTX3”. J. Clin. Immunol., 2008; 28, 1-13. [10] Yang, H.S., Woo, J.E., Lee, ...
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Systemic pentraxin 3 levels reflect vascular enhancement and progression in Takayasu arteritis
... Figure 2 Pentraxin-3 (PTX3) levels reflect ongoing vascular inflammation in Takayasu arteritis (TA). (A) Plasma concentrations of PTX3 in patients with TA and matched systemic lupus erythematosus (SLE) ...
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Can Pentraxin-3 be a Candidate Marker in the Follow-Up of the Patients With Behçet’s Disease?
... as a part of daily clinical practice. Plasma (ethylenediaminetetraacetic acid-anticoagulated) samples were stored at -200 °C until analysis. Plasma PTX-3 concentration was measured by using the commercially ...
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The implication of calcium score and pentraxin 3 in non invasive identification of significant coronary artery stenosis in chronic stable angina pectoris
... Pentraxin-3 (PTX-3), initially proposed as an early in- dicator of innate immunity and inflammatory response, is also expressed abundantly in cardiac tissue during in- flammatory processes, in the ...
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Diagnostic value of Pentraxin 3 in patients with sepsis and septic shock in accordance with latest sepsis 3 definitions
... long pentraxin subfamily [11–13]. Production of PTX-3 is strongly induced by cytokines like interleukin- 1, tumor necrosis factor α (TNF-α) and by toll-like receptor (TLR) agonists, but not by interleukin 6 ...
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Pentraxin 3 as a marker of disease severity and risk of death in patients with necrotizing soft tissue infections: a nationwide, prospective, observational study
... Pentraxin-3 (PTX3) is a multifunctional pattern- recognition molecule released at the onset of inflamma- tion as part of the innate immune system by activating the classical and lectin complement pathways ...
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The Relationship between Serum Pentraxin 3 Levels and Severity of Coronary Heart Disease
... DOI: 10.4236/wjcd.2018.87036 377 World Journal of Cardiovascular Diseases patients with normal coronary angiography, and the second group included 68 patients with CAD. SYNTAX score was used to determine the extent of ...
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SERUM PENTRAXIN-3 (PTX3) LEVEL AS IN-HOSPITAL MAJOR CARDIOVASCULAR EVENTS PREDICTOR IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION
... Subject’s clinical and demographic characteristics who admitted in the ER with acute myocardial infarction as working diagnose were recorded. Blood samples were taken from all subjects upon admission. The samples were ...
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Alveolar pentraxin 3 as an early marker of microbiologically confirmed pneumonia: a threshold-finding prospective observational study
... Pentraxin 3 (PTX3) is an acute-phase inflammatory me- diator produced at the site of infection that can be assayed in a few hours [15]. In the lungs, epithelial cells, endothe- lial cells and leukocytes can ...
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A long pentraxin-3-derived pentapeptide for the therapy of FGF8b-driven steroid hormone-regulated cancers
... long pentraxin-3 (PTX3) binds various FGFs, including FGF2 and FGF8b, thus inhibiting the angiogenic and tumorigenic activity of androgen-regulated tumor ...
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Alveolar pentraxin 3 as an early marker of microbiologically confirmed pneumonia: a threshold finding prospective observational study
... Pentraxin 3 (PTX3) is an acute-phase inflammatory me- diator produced at the site of infection that can be assayed in a few hours [15]. In the lungs, epithelial cells, endothe- lial cells and leukocytes can ...
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Diagnostic and prognostic value of interleukin 6, pentraxin 3, and procalcitonin levels among sepsis and septic shock patients: a prospective controlled study according to the Sepsis 3 definitions
... Pentraxin 3 (PTX3), which belongs to the long pen- traxin family, is expressed in a variety of cells during various inflammatory processes, including sepsis ...
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Incorporation of Pentraxin 3 into Hyaluronan Matrices Is Tightly Regulated and Promotes Matrix Cross-linking
... I), pentraxin 3 (PTX3), and TNF-stimulated gene-6 (TSG-6) have been identi- fied as being critical for COC matrix formation, its supramo- lecular organization and the molecular mechanism of COC matrix ...
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Driver mutations (JAK2V617F, MPLW515L/K or CALR), pentraxin-3 and C-reactive protein in essential thrombocythemia and polycythemia vera
... can be detected in 60 to 65% of patients, MPLW515L/K in about 5% and CALR mutation in about 20 to 25%. The understanding that an array of somatic mutations contrib- utes to the biology of these disorders [8, 9] prompted ...
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Prognostic Value of White Blood Cell Count, C-reactive protein, and Pentraxin-3 Levels in Patients with Acute Paraquat Poisoning
... Our results demonstrated that the levels of all three inflammatory biomarkers increased after acute paraquat poisoning. This is consistent with the previous findings that inflammatory process is involved in the ...
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Obesity and high waist circumference are associated with low circulating pentraxin-3 in acute coronary syndrome
... Plasma glucose, HDL cholesterol and plasma triglycer- ides were measured using standard methods. Plasma insulin was measured by ELISA (Insulin Human Ultra- sensitive ELISA; DRG Instruments, Marburg, Germany). Insulin ...
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Long Pentraxin 3 as a Predictive Marker of Mortality in Severe Septic Patients Who Received Successful Early Goal Directed Therapy
... PTX3, pentraxin 3; PCT, procalcitonin; CRP, C-reactive protein; DNI, delta neutrophil index; APACHE, acute physiology and chronic health evaluation; SOFA, sequential organ fail- ure ...
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