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Peritoneal Fibrosis

SIRT1-modified human umbilical cord mesenchymal stem cells ameliorate experimental peritoneal fibrosis by inhibiting the TGF-β/Smad3 pathway

SIRT1-modified human umbilical cord mesenchymal stem cells ameliorate experimental peritoneal fibrosis by inhibiting the TGF-β/Smad3 pathway

... of peritoneal fibrosis, mesenchymal stem cell (MSC) transplantation has been reported to be promising ...ate peritoneal fibrosis and improve peritoneal damage in rat models ...into ...

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Original Article Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/ MyD88/NF-κB signaling pathway

Original Article Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/ MyD88/NF-κB signaling pathway

... (LPS)-induced peritoneal fibrosis and its underlying ...human peritoneal mesothelial cell line (HMrSV5) was treated with LPS, followed by treatment with different concentrations of dioscin ...as ...

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Curcumin ameliorates peritoneal fibrosis via inhibition of transforming growth factor activated kinase 1 (TAK1) pathway in a rat model of peritoneal dialysis

Curcumin ameliorates peritoneal fibrosis via inhibition of transforming growth factor activated kinase 1 (TAK1) pathway in a rat model of peritoneal dialysis

... in peritoneal EMT and ...inhibited peritoneal fibrosis of rats with long-term peritoneal dialysis ...suppresses peritoneal fibrosis partly through inhi- biting TGF-β1/TAK1 ...

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Induction of gastric cancer cell adhesion through transforming growth factor-beta1-mediated peritoneal fibrosis

Induction of gastric cancer cell adhesion through transforming growth factor-beta1-mediated peritoneal fibrosis

... that peritoneal fibrosis may stimulate the adherence capabil- ity of gastric cancer cells to the peritoneum, which is consistent with previous reports showing that TGF-b1 enhanced tumor-mesothelial cell ...

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Original Article The protective effects of melatonin on peritoneal fibrosis induced by high glucose peritoneal dialysis in rats

Original Article The protective effects of melatonin on peritoneal fibrosis induced by high glucose peritoneal dialysis in rats

... non-biocompatible peritoneal dialysis fluid at a low pH, which can lead to peritoneal fibrosis over a long period of time, resulting in the loss of peritoneal struc- ture and function ...to ...

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Delayed administration of suramin attenuates peritoneal fibrosis in rats

Delayed administration of suramin attenuates peritoneal fibrosis in rats

... All the experiments were performed in Thirty-six 6– 8 week old Male Sprague-Dawley rats (170 ± 10 g) pur- chased from B&K laboratory animal Corp (Shanghai, China). Rats were randomly separated into six groups with 6 ...

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A microrna screen to identify regulators of peritoneal fibrosis in a rat model of peritoneal dialysis

A microrna screen to identify regulators of peritoneal fibrosis in a rat model of peritoneal dialysis

... the peritoneal mesothelial cells had acquired a mesenchymal phenotype through the process of EMT and had enhanced production of extracellular matrix components ...of peritoneal fibrosis, a miRNA ...

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Tamoxifen and bone morphogenic protein-7 modulate fibrosis and inflammation in the peritoneal fibrosis model developed in uremic rats

Tamoxifen and bone morphogenic protein-7 modulate fibrosis and inflammation in the peritoneal fibrosis model developed in uremic rats

... PM fibrosis development, particularly in the PF/CKD ...of peritoneal inflam- mation and the uremic environment boosts the risk of fibrosis development and significant loss of peritoneal ...

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Functional molecules in mesothelial to mesenchymal transition revealed by transcriptome analyses

Functional molecules in mesothelial to mesenchymal transition revealed by transcriptome analyses

... Peritoneal fibrosis is a common complication of abdominal and pelvic surgery, and can also be triggered by peritoneal dialysis, resulting in treatment ...settings, fibrosis is driven by ...

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Hepatocyte growth factor signalizes peritoneal membrane failure in peritoneal dialysis

Hepatocyte growth factor signalizes peritoneal membrane failure in peritoneal dialysis

... human peritoneal mesothelial cells constitutively synthesized HGF [13], and that treatment of human peritoneal mesothelial cells with HGF blocks high glucose-induced epithelial-to-mesenchymal transi- tion ...

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Fibrosis of mesothelial cell-induced peritoneal implantation of ovarian cancer cells

Fibrosis of mesothelial cell-induced peritoneal implantation of ovarian cancer cells

... cell fibrosis promoted the invasiveness of SKOV3 ...the peritoneal fibrosis microenvironment pro- moted the invasion of ovarian cancer cells and prevented the fibrosis of peritoneal ...

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Evolution of a Disseminated Peritoneal Leiomyomatosis: About a Case

Evolution of a Disseminated Peritoneal Leiomyomatosis: About a Case

... Disseminated peritoneal leiomyomatosis (DPL) is a benign tumor of smooth muscle ...tiple peritoneal nodules simulating peritoneal carcinosis [1] ...

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Cinacalcet versus standard treatment for chronic kidney disease: a protocol for a systematic review and meta-analysis

Cinacalcet versus standard treatment for chronic kidney disease: a protocol for a systematic review and meta-analysis

... or renal dialysis/ or hemodialysis, home/ or peritoneal dialysis/ or peritoneal dialysis, continuous ambulatory/ or renal insufficiency, chronic/ or kidney failure, chronic/ or (((chroni[r] ...

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A study of peritoneal adhesions

A study of peritoneal adhesions

... Prolonged peritoneal exposure to air during laparotomy and subsequent mesothelial dessication may contribute to de novo adhesion formation at sites remote from the operative ...the peritoneal cavity is ...

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Detection of peritoneal metastases

Detection of peritoneal metastases

... Irregular, ‘cake-like’ masses are seen most often with ovarian cancer [36] . Densely calcified omental ‘cake’ has been reported in metastatic serous cystadenocarcinoma [37] . The stellate pattern of mesenteric or omental ...

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Gastric cancer cell supernatant causes apoptosis and fibrosis in the peritoneal tissues and results in an environment favorable to peritoneal metastases, in vitro and in vivo

Gastric cancer cell supernatant causes apoptosis and fibrosis in the peritoneal tissues and results in an environment favorable to peritoneal metastases, in vitro and in vivo

... Male C57BL/6 mice (eight weeks old, weighing 20 ± 2 g) were used in the present study. The experiment followed the guidelines for the use of Laboratory Animals in Re- search and Teaching. The mice were fed a standard ...

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Examination of the morphology of bacteria adhering to peritoneal dialysis catheters by scanning and transmission electron microscopy

Examination of the morphology of bacteria adhering to peritoneal dialysis catheters by scanning and transmission electron microscopy

... Examination of the Morphology of Bacteria Adhering to Peritoneal Dialysis Catheters by Scanning and Transmission Electron Microscopy.. We examined Tenckhoff peritoneal catheters by scann[r] ...

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Original Article Malignant peritoneal mesothelioma presented as peritoneal adenocarcinoma or primary ovarian cancer: Case series and review of the clinical and immunohistochemical features

Original Article Malignant peritoneal mesothelioma presented as peritoneal adenocarcinoma or primary ovarian cancer: Case series and review of the clinical and immunohistochemical features

... Among 8 patients we evaluated, we thought that optimal cytoreduction could be achieved with primary surgery, especially in patients pre- sented with ovarian mass, thus primary surgery was performed. In other patients, ...

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Macrophage and Innate Lymphoid Cell Interplay in the Genesis of Fibrosis

Macrophage and Innate Lymphoid Cell Interplay in the Genesis of Fibrosis

... The fibrosis cascade progresses following the insult to cells and subsequent release of mediators, such as IL-13, connective tissue growth factor (CTGF), and TGF-β, that operates downstream of initial cellular ...

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The impact of peritoneal dialysis-related peritonitis on mortality in peritoneal dialysis patients

The impact of peritoneal dialysis-related peritonitis on mortality in peritoneal dialysis patients

... Results: A total of 1321 patients were included. The mean age was 48.1 ± 15.3 years, 41.3% were female, and 23.5% with diabetes mellitus. The median (interquartile) follow-up time was 34 (21 – 48) months. After adjusting ...

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