Peritoneal mesothelioma
Analysis of prognostic factors of patients with malignant peritoneal mesothelioma
... malignant peritoneal mesothelioma (DMPM) patients treated with systemic pemetrexed alone ...the peritoneal cavity, higher local tumoricidal effect, lower nephric toxicity, and lower systemic toxicity ...
8
Content validity and ePRO usability of the BPI-sf and “worst pain” item with pleural and peritoneal mesothelioma
... pleural mesothelioma; 50% of those with peritoneal ...with peritoneal mesothelioma were identified and interviewed, one of whom had both pleural and peri- toneal ...
10
Benign multicystic peritoneal mesothelioma: a case report
... Benign multicystic peritoneal mesothelioma is a very rare benign cystic tumor. This lesion has a non-specific appearance on imaging which does not permit differen- tial diagnosis from other cystic lesions ...
5
<p>Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma: patient selection and special considerations</p>
... Malignant peritoneal mesothelioma (MPM) is a rare, aggressive malignancy that typically presents with vague symptoms, ascites, and/or diffuse peritoneal ...the peritoneal cavity, spread beyond ...
11
Clinical implications of novel activating EGFR mutations in malignant peritoneal mesothelioma
... malignant mesothelioma [10-12]. Also malignant mesothelioma, like NSCLC, is a highly lethal cancer that can arise de novo in the pleural cavity; but unlike NSCLC, mesothelioma can also origi- nate in ...
10
Ectopic ACTH secretion (EAS) associated to a well-differentiated peritoneal mesothelioma: case report
... Case presentation: A 43-year-old hispanic woman with a 20 year history of treatment resistant diabetes mellitus and arterial hypertension. She had a full moon face, a buffalo hump, increased volume in both ...
6
Detecting germline BAP1 mutations in patients with peritoneal mesothelioma: benefits to patient and family members
... with peritoneal mesothelioma, led to meetings with family members in which we explained the potential advantages and possible disadvantages of genetic testing for BAP1 mutations, consistent with the ...
7
CpG oligodeoxynucleotides exert remarkable antitumor activity against diffuse malignant peritoneal mesothelioma orthotopic xenografts
... malignant peritoneal mesothelioma (DMPM) is an uncommon malignancy that develops from the meso- thelial cells lining the peritoneal cavity and accounts for 10–20 % of all mesotheliomas ...
8
Peritoneal Mesothelioma – A Review Concerning Surgical Management, Prognostic Factors, Future Advances and Our Experience in an Asian Population.
... vaginalis. Peritoneal mesothelioma accounts for about one quarter of all mesotheliomas with three main pathological subtypes: epithelial, sarcomatous and ...for peritoneal mesothelioma in an ...
9
Anti-tumor activity of selective inhibitors of XPO1/CRM1- mediated nuclear export in diffuse malignant peritoneal mesothelioma: the role of survivin
... malignant peritoneal mesothelioma (DMPM), exclusively relies on exportin 1 (XPO1/ CRM1) to be shuttled into the cytoplasm and perform its anti-apoptotic ...
14
Antitumor activity of miR-34a in peritoneal mesothelioma relies on c-MET and AXL inhibition: persistent activation of ERK and AKT signaling as a possible cytoprotective mechanism
... malignant peritoneal mesothelioma (DMPM) is an uncommon though locally aggressive tumor that develops from mesothelial cells lining the peritoneal cavity ...
14
miR-380-5p-mediated repression of TEP1 and TSPYL5 interferes with telomerase activity and favours the emergence of an “ALT-like” phenotype in diffuse malignant peritoneal mesothelioma cells
... malignant peritoneal mesothelioma (DMPM), a fatal malignancy with limited therapeutic options, is of utmost importance for the fruitful management of the ...
14
Effects of sex hormones on survival of peritoneal mesothelioma
... This is a retrospective study of prospectively collected data of 52 consecutive patients with PM who underwent CRS and HIPEC by the same surgical team at St George Hospital in Sydney, Australia, between April 1996 and ...
7
Indolent peritoneal mesothelioma: PI3K-mTOR inhibitors as a novel therapeutic strategy
... in-depth molecular characterisation of these patients is required to elucidate the oncogenic drivers of MPeM. Targeting the loss of function of tumour suppressors PTEN and NF2 is pharmacologically challenging, and new ...
6
Original Article Malignant peritoneal mesothelioma presented as peritoneal adenocarcinoma or primary ovarian cancer: Case series and review of the clinical and immunohistochemical features
... Mesotheliomas may reveal a wide range of his- tologic pattern; particularly epithelioid meso- theliomas with prominent tubulopapillary pat- tern may closely mimic serous carcinomas of ovaries or peritoneum. Ovarian tumor ...
7
BAP1 haploinsufficiency predicts a distinct immunogenic class of malignant peritoneal mesothelioma
... Mesothelioma is typically diagnosed in the advanced stages of the disease. A combination of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemo- therapy (HIPEC), sometimes followed by normothermic ...
12
Distinctive clinical characteristics of malignant mesothelioma in young patients
... for peritoneal mesothelioma ...for mesothelioma [17, 18]. However little is known about mesothelioma in the ...[22], mesothelioma in the young is less likely to be due to occupational ...
8
Immunotherapy advances for mesothelioma treatment
... organs. Mesothelioma is typically divided into four classifications: pleural mesothelioma (mesothelioma of the lungs); peritoneal mesothelioma (mesothelioma of the abdomen); ...
80
Original Article Synchronous pleural and peritoneal malignant mesothelioma: a case report and review of literature
... of peritoneal mesothelioma remains still un- known, although it has been pro- posed that asbestos fibers from the lung can be transported to the peritoneum and abdominal organs via the lymphatic ...
6
Pathology of mesothelioma
... pleural mesothelioma [12], ovarian serous papillary adenocarci- noma or peritoneal serous carcinoma for peritoneal mesothelioma ...pleural mesothelioma and carcinosarcoma of the female ...
5