Persistent gestational trophoblastic disease
Low-risk persistent gestational trophoblastic disease treated with low-dose methotrexate: efficacy, acute and long-term effects
... low-risk persistent gestational trophoblastic ...their disease giving an overall cure of ...low-risk persistent trophoblastic ...
5
Persistent gestational trophoblastic disease: results of MEA (methotrexate, etoposide and dactinomycin) as first-line chemotherapy in high risk disease and EA (etoposide and dactinomycin) as second-line therapy for low risk disease
... Summary Persistent gestational trophoblastic disease is potentially fatal, but the majority of patients are cured with ...risk disease and etoposide and dactinomycin (EA) as second-line ...
6
Factors Associated with Smoking Behaviors among Military Cadets of King Khalid Military Academy (KKMA), Riyadh, Saudi Arabia (2015-2016)
... for persistent gestational trophoblastic ...marked trophoblastic overgrowth comprising of cytotrophoblast, intermediate trophoblast and syncytiotrophoblast are features of ...to ...
6
A study of factors affecting regression of βhCG in gestational trophoblastic disorders
... to persistent disease are assessed by a case control ...developing persistent trophoblastic disease were taken as cases and those with normal regression of βhCG were taken as ...
6
Study of gestational trophoblastic diseases at a tertiary care hospital in India
... of Gestational trophoblastic ...of gestational trophoblastic diseases was noted which included choriocarcinoma with brain metastasis without lung involvement, Epitheloid trophoblastic ...
6
Gestational trophoblastic neoplasia with retroperitoneal metastases: A fatal complication
... Pulmonary metastases in most cases are treatable with combined chemotherapy but sometimes it is necessary to perform thoracotomy in order to remove a pulmonary module that does not resolve after chemotherapy [12]. Brain ...
6
Illness Perception in Gestational Trophoblastic Disease Patients: How Mental Representations Affect Anxiety, Depression, and Infertility Related Stress
... their disease could weaken the sense of death threat generally evoked from a cancer diagnosis preventing them from developing persistent and severe feelings of sadness, hopelessness, worth- lessness, and ...
15
Conservative Management, Follow-up and Perinatal Outcomes After Gestational Trophoblastic Disease with Coexistent Normal Fetus: Case Report
... cases, persistent or recurrent disease is diagnosed by elevated or persistent serum levels of β-hCG ...placental trophoblastic proliferation, however, the postnatal karyotype was ...
5
Prospective study of natural history, follow- up, treatment and outcome of patients with gestational trophoblastic disease at IOG
... Clinicians frequently assume that an elevated hCG implies that a patient is pregnant or has GTD or recurrent GTN, even when apart from the pregnancy test, no clinical evidence was found to support such a diagnosis. In ...
131
Gestational Ovarian Choriocarcinoma: A Review of the Literature and Presentation of a Perplexing Case
... rare disease. The presentation of persistent nausea, vomiting (morning sickness) likely was a result of extremely elevated β-hCG as can be common in gestational trophoblastic ...in ...
6
Gestational Trophoblastic Diseases: A Review of the Clinical Presentation and Management at the Alex Ekwueme Federal University Teaching Hospital Abakaliki
... of persistent rise or plateau of B-hCG and in cases of ...of persistent GTD may be decreased with prophylactic chemothe- ...for persistent gesta- tional trophoblastic disease or whom ...
8
Gestational Trophoblastic Disease
... first undetected level of beta HCG following evacuation is about 9-11 weeks (Figure 2). Any rise in levels should prompt a pelvic examination and further evaluation for persistent of the disease or ...
7
Outcome of treatment with EMA/EP (etoposide methotrexate and actinomycin-D/ etoposide and cisplatin) regimen in gestational trophoblastic neoplasia
... of persistent GTN with rising or plateau of serum β-HCG ...the disease was confined to the uterus, stage I or nonmetastatic form was perceived; on the other hand, when a metastatic lesion was detected in ...
5
Unusual Presentation of Invasive Mole: A Case Report
... or trophoblastic disease metastasis of invasive mole commonly in lungs and after lungs in vagina, cer- vix, broad ligament (16, 19), in our case metasta- sis to lung and ovary and omentum was ...Non ...
5
Efficacy and Risk Factors Associated to Resistance to Single Agent Chemotherapy in Low Risk Gestational Trophoblastic Neoplasia
... low-risk gestational trophoblastic neoplasia and also identify prognostic factors associated with treatment failure, necessitating second line ...of Gestational Trophoblastic Disease in ...
6
Pulmonary function in patients with trophoblastic disease treated with low-dose methotrexate
... Pulmonary function in patients with trophoblastic disease treated with low-dose methotrexate AM Gillespie1, PC Lorigan1, CR Radstone1, JC Waterhouse2, RE Coleman1 and BW Hancock1 'Sheffi[r] ...
5
Thoracotomy in refractory gestational trophoblastic neoplasia with lung metastasis after normalization of serum beta human chorionic gonadotropin (β-hCG) with salvage chemotherapy
... All surgical specimens were analyzed. Positive pathologic findings of the resected specimen were defined as tropho- blastic cells documented in the specimen, whereas necrotic or hemorrhagic tissue, fibrosis nodules, or ...
6
Comparison of the efficacy of methotrexate and actinomycin D in the treatment of patients with stage I low risk gestational tro-phoblastic neoplasia (GTN)
... Background: Gestational trophoblastic neoplasia (GTN) refers to malignant lesions that arise from abnormal proliferation of placental ...low-risk gestational trophoblastic neoplasia ...
6
How and Why Do Gestational Trophoblastic Neoplasms Overproduce Human Chorionic Gonadotropin?
... of gestational trophoblastic dis- eases (GTDs) from normal intrauterine pregnancy as well as for determination of the therapeutic response to surgical tumor removal followed by ...
6
Characterization of a carboxyterminal peptide fragment of the human choriogonadotropin beta subunit excreted in the urine of a woman with choriocarcinoma
... Our data obtained on a small number of patients with gestational trophoblastic neoplasia give indication that hCG# carboxyterminal fragments are commonly excreted in the urine of women w[r] ...
12