Personalised medicine for cancer
Targeted therapy in metastatic colorectal cancer – An example of personalised medicine in action
... of personalised medicine, cancer diagnosis, prognosis and treatment decisions were mainly based upon the histopathologic characteristics of the ...of personalised medicine will help ...
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Stratified, precision or personalised medicine? Cancer services in the “real world” of a London hospital
... breast cancer, elements of the cancer pathway were shared and we met Chris during our pilot study receiving treatment for a different ...Guy’s cancer is not contagious; you can ’t catch it off ...
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Personalised medicine for nonsmall cell lung cancer
... lung cancer, the College of American Pathologists, the International Association for Study of Lung Cancer and the Association of Molecular Pathologists have published guidelines [71] that recommend, at ...
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Big data in cancer research : DNA sequencing and personalised medicine
... Cancer is a complex disease The multidimensional nature of the cancer (genome, proteome, epigenome, kinome, etc.) has to be considered to unravel the complexity of the disease. Mathematical models and ...
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Combating pancreatic cancer with PI3K pathway inhibitors in the era of personalised medicine
... pancreatic cancer is driven by activating mutations in KRAS, which in turn activates PI3K signalling through the p110α subunit, along with another pathway component PDK1, indicating that a large proportion of ...
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PCR based zebrafish model for personalised medicine in head and neck cancer
... study cancer cell proliferation, metas- tasis, tumour angiogenesis and drug testing [9, 13, ...for personalised colon and gastric cancer drug testing using patient-derived xenografts [7, ...of ...
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Consequences of Biomarker Analysis on the Cost-Effectiveness of Cetuximab in Combination with FOLFIRI as a First-Line Treatment of Metastatic Colorectal Cancer: Personalised Medicine at Work
... Considering the findings of our study, it should be noted that our results may have been limited by the fact that post hoc analysis or retrospective auditing of clinical studies is not generally considered the best ...
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Methodological Approaches towards Personalised Cancer Medicine
... Personalised medicine aims to treat the right patient with the right combination of drugs at the right time to achieve maximum efficacy while minimising side-effects and resistance ...in cancer ...
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Personalised medicine in asthma: from curative to preventive medicine
... preventive medicine and the use of the targeted therapies now being developed for chronic diseases, as well as for ...predictive, personalised and participative) ...
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Personalised medicine in Canada: a survey of adoption and practice in oncology, cardiology and family medicine
... of cancer within Ontario’s healthcare system, and recommended physician education, public education and improved coordination of healthcare delivery and genetic testing ...
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Model-based recursive partitioning for stratified and personalised medicine
... alised medicine is an important topic for drug development (see reports US Food and Drug Administration, 2013; European Medicines Agency, 2014) and the topic is currently frequently discussed in academia ...breast ...
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A personalised medicine approach for ponatinib-resistant chronic myeloid leukaemia.
... patients and methods Detailed experimental procedures are in supplementary Methods, available at Annals of Oncology online. Brie fly, tissues were collected following informed consent and ethical approval from the ...
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Circulating microRNA biomarkers in melanoma: tools and challenges in personalised medicine
... in cancer, this may not always be a safe ...(i.e., cancer specific and/or study specific), therefore endogenous normalizers should be identified for samples specific to each study using high throughput ...
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Big Data for Population Health and Personalised Medicine through EMR Linkages
... Age-specific trends in adult liver cancer and cirrhosis mortality in Qidong, China, 1980-2009... Cigarette consumption & lung cancer in US..[r] ...
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Biological network analysis: from topological indexes to biological applications towards personalised medicine.
... Another important aspect of the biological data we investigated, that should be considered, refer to their temporal and spatial characteristics. Protein compo- sition varies in time and in different families of cells. A ...
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Personalised medicine in sleep respiratory disorders: focus on obstructive sleep apnoea diagnosis and treatment
... and cancer [15] and the relevant effects of chronic intermittent hypoxia in visceral fat [16, ...if personalised medicine has to be implemented in basic and clinical research on OSA, we are still in ...
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NMR-based pharmacometabonomics: A new paradigm for personalised or precision medicine
... Kwon et al[83] used an NMR-based pharmacometabonomics approach to predict the nephrotoxicity (kidney toxicity) of the anti-cancer drug cisplatin in rats. Nephrotoxicity is a significant issue for cisplatin and can ...
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Towards personalised therapy for lymphangioleiomyomatosis: lessons from cancer
... pulmonary medicine and oncology within the LAM research and clinical care ...a personalised approach with durable, complete remission is an achievable goal, with opportunities to use advances in ...
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European Alliance for Personalised Medicine. INNOVATION and PATIENT ACCESS to PERSONALISED MEDICINE
... personalized medicine that health professionals have to address with their patients, in order to maintain the effectiveness of the information exchange and the patients’ engagement, is related to the increased ...
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Personalised Medicine in MS
... Subgroup analysis of Clinical Trials and its impact on personalized therapeutic choices. in MS :.[r] ...
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