PFK, phosphofructokinase
Modulation of phosphofructokinase (PFK) from Setaria cervi, a bovine filarial parasite, by different effectors and its interaction with some antifilarials
... cervi PFK was present in its cytosolic ...of PFK in the mus- culature of the ...of PFK by p-CMB could be protected to a significant extent by pretreatment with cysteine or ...cervi PFK exhib- ...
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PFKM gene defect and glycogen storage disease GSDVII with misleading enzyme histochemistry
... Results: Both siblings had juvenile-onset exercise intolerance with cramping and infrequent myo- globinuria. Muscle biopsy showed extralysosomal glycogen accumulation, but because of normal phosphofructokinase ...
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THE EFFECT OF SEROTONIN (5 HYDROXYTRYPTAMINE) ON GLYCOLYSIS IN THE PERFUSED VENTRICLE OF THE FRESHWATER BIVALVE ANODONTA CYGNEA: EVIDENCE FOR PHOSPHORYLATION/DEPHOSPHORYLATION CONTROL OF PHOSPHOFRUCTOKINASE
... enzymes, phosphofructokinase (PFK) and pyruvate kinase (PK), from molluscan tissues are partly modulated v i a phosphorylation/dephosphorylation ...of PFK from molluscan tissues by endogenous ...
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Spinach aldolase interactions with rabbit, chicken, and fish muscle phosphofructokinase 1
... fm PFK-1 shows a different pattern from cm ...fm PFK-1 differently from cm PFK-1. Initially, 300 nM fm PFK-1 (●) always showed stimulations of activity immediately after dilu- tion in the ...
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Hexokinase and phosphofructokinase activity and intracellular distribution correlate with aggressiveness and invasiveness of human breast carcinoma
... and PFK was further analyzed in terms of the ratio of the activities of the enzymes in tumor samples relative to non-tumor samples, according to the stage of invasion and TNM classification of the ...and ...
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Characterization of the enzymatic defect in late onset muscle phosphofructokinase deficiency New subtype of glycogen storage disease type VII
... cell PFK showed the presence of a few M-containing isozymes in addition to the predominant L4 species, indicating that the genetic lesion is a "leaky" mutation of the gene coding for the M ...
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N-Terminal Presequence-Independent Import of Phosphofructokinase into Hydrogenosomes of Trichomonas vaginalis
... chinery can import heterologous ATP-PFKs. When we expressed complete ScATP-PFK in T. vaginalis under the control of the TvATP-PFK1 promoter, immunofluorescence microscopy re- vealed predominantly cytosolic ...
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Thermally induced changes in intracellular pH and modulators of phosphofructokinase in trout white muscle
... In rat and frog fast-twitch muscles, [FBP] transiently increases shortly after the initiation of muscular activity (Aragón et al. 1980; Minatogawa and Hue, 1984; Bassols et al. 1986; Gerhard et al. 1990). A similar, but ...
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The influence of PFK-II overexpression on neuroblastoma patients’ survival may be dependent on the particular isoenzyme expressed, PFKFB3 or PFKFB4
... and normal proliferating cells. In fact, studies in recent years revealed that PFKFB3/PFKFB4 isoenzymes are excellent candidates for glycolysis targeting, especially in cancer cells [5, 6]. PFKFB3 and PFKFB4 are cancer ...
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The Phosphofructokinase and Pyruvate Kinase Genes in Apis andreniformis and Apis cerana indica: Exon Intron Organisation and Evolution
... regarding PFK and PK-like ...combined PFK and PK-like nucleotide sequences was congruent with phylogenetic tree based on the molecular sequences of five genes and the behavioural states (Raffiudin & ...
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Heterogeneity of the molecular lesions in inherited phosphofructokinase deficiency
... Human phosphofructokinase (PFK; EC 2.7.1.11) exists in tetrameric isozymic forms. Muscle and liver contain the homotetramers M4 and L4, whereas erythrocytes contain five isozymes composed of M (muscle) and ...
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Analysis of the regulatory mechanism of deoxynivalenol production using omics
... Phosphofructokinase (PFK) is an enzyme that acts on fructose-6-phosphate and catalyzes one of the key regulatory and rate-limiting steps of glycolysis (Mor et al. 2011). PFK1 converts fructose-6-phosphate ...
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Sheep liver phosphofructokinase : a comparison of the primary structure with those of other mammalian isozymes : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Biochemistry at Massey University
... Despite the fact that F26BP is a potent inhibitor of F 1 6BPase (Van Schaftingen and Hers, 1 98 1 a; Pilki s tl ll., 198 1 b; Ganson and Fromm, 1982), there is good experimental evidence that this inhibition is not ...
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Muscle phosphofructokinase deficiency Biochemical and immunological studies of phosphofructokinase isozymes in muscle culture
... muscle phosphofructokinase (PFK; EC ...normal PFK activity and normal ...three PFK subunits, M (muscle-type), L (liver-type), and P (platelet-type) and contain multiple homotetrameric and ...
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Regulation of binding of phosphofructokinase to myofibrils in the red and white muscle of the barred sand bass, Paralabrax nebulifer (Serranidae)
... The isozymic forms of PFK in fish are unknown, but results from studies on the kinetic and allosteric properties of PFK in extracts from white and red muscle suggest that the enzyme may [r] ...
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Effects of insulin infusion on human skeletal muscle pyruvate dehydrogenase, phosphofructokinase, and glycogen synthase Evidence for their role in oxidative and nonoxidative glucose metabolism
... (GS), phosphofructokinase (PFK), or pyruvate dehydrogenase (PDH) in skeletal muscle regulates intracellular glucose metabolism, subjects were studied basally and during euglycemic insulin infusions of 12, ...
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Enzymatic basis for bioenergetic differences of alveolar versus peritoneal macrophages and enzyme regulation by molecular O2
... The activities of two key glycolytic enzymes, pyruvate kinase Py Ki and phosphofructokinase PFK, and of cytochrome oxidase Cy OX, the terminal electron transport chain enzyme, were also [r] ...
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An investigation into the binding of sheep heart phosphofructokinase to an intracellular component : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University
... Ouchterlony Immunodiffusion Analysis of the Cross Reactivity of Anti-Sheep Heart Antibodies With Pure Sheep Liver PFK.... LIST OF TABLES.[r] ...
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Regulation of Metabolic Pathways PVY-RNA Biosynthesis in Tobacco: Glycolytic Pathway
... The activities of key enzymes of the glycolytic pathway, 6-phosphofructokinase (PFK), fructose- bisphosphatase (FBPase) and pyruvate kinase (PK), were not influenced by PVY infection (data not shown; the ...
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Adaptation to HIF 1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas
... of PFK-1 [32], and in several studies [reviewed in [33]] forced over-expression of PFK-1 has not led to faster glycolytic ...which PFK-1 overexpression studies have been performed started with normal ...
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