Phenotypic heterogeneity
Phenotypic heterogeneity is a selected trait in natural yeast populations subject to environmental stress
... Cell-to-cell heterogeneity is typically measured in relation to a specific ...increased heterogeneity was the focus of our ...to-cell heterogeneity, where the heterogeneity relates to ...
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Proteomic study uncovers molecular principles of single-cell-level phenotypic heterogeneity in lipid storage of Nannochloropsis oceanica
... Population heterogeneity is a common phenomenon in microbial ...elicit phenotypic heterogeneity in isogenic microbial ...cultures. Phenotypic heterogeneity occurs under conditions rel- ...
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The role of spatial variations of abiotic factors in mediating intratumour phenotypic heterogeneity
... mediating phenotypic selection of cancer ...different phenotypic variants within the same ...stable phenotypic heterogeneity and supports the presence of hypoxic cells resistant to cytotoxic ...
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Noise-Driven Phenotypic Heterogeneity with Finite Correlation Time in Clonal Populations
... clonal phenotypic heterogeneity in playing key roles in phenomena such as cellular bet-hedging and decision making, as in the case of the phage- λ lysis/lysogeny and ...and heterogeneity within ...
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Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance
... The influence of the gut microbiome on metabolic and behavioral traits is widely accepted, though the microbiome-derived metabolites involved remain unclear. We carried out untargeted urine 1 H-NMR spectroscopy-based ...
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<p>Impact Of Phenotypic Heterogeneity Of Insomnia On The Patients’ Response To Cognitive-Behavioral Therapy For Insomnia: Current Perspectives</p>
... clearly phenotypic heterogeneity of ID, the limited number of studies and the methodological variability do not allow a strong conclusion about how to subtype or phenotype ID in a way that will predict con ...
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Phenotypic heterogeneity and genetic modification of P102L inherited prion disease in an international series
... The largest kindred with inherited prion disease P102L, historically Gerstmann-Stra«ussler-Scheinker syndrome, originates from central England, with e¤migre¤s now resident in various parts of the English-speaking world. ...
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The role of spatial variations of abiotic factors in mediating intratumour phenotypic heterogeneity
... different phenotypic vari- ants within the same ...stable phenotypic heterogeneity and supports the presence of hypoxic cells resistant to cytotoxic therapy prior to ...intratumour ...
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<p>Functional aspects, phenotypic heterogeneity, and tissue immune response of macrophages in infectious diseases</p>
... macrophage phenotypic heterogeneity has been investigated since the 1980s, and more recent studies have identi fi ed a diverse spectrum of phenotypic ...macrophage phenotypic subpopulations, ...
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Growth-dependent recombinant product formation kinetics can be reproduced through engineering of glucose transport and is prone to phenotypic heterogeneity
... of phenotypic heterogeneity on bioprocess performance ...microbial phenotypic heter- ogeneity is related to nutrient assimilation and transition [22–24], but more rarely to the expression of ...
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Phenotypic heterogeneity of peripheral monocytes in healthy dogs
... In conclusion, canine monocytes display phenotypic heterogeneity and may be divided into three populations based on CD14 and MHC II expression. Functional and transcriptomic studies will be necessary to ...
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Phenotypic heterogeneity of latent autoimmune diabetes in adults identified by body composition analysis
... Latent autoimmune diabetes in adults accounts for roughly 10% of all cases of diabetes. The largest LADA cohorts analyzed so far [4-7] revealed a significant degree of het- erogeneity of this form at the immunological ...
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Genotypic and Phenotypic Heterogeneity among Mycobacterium tuberculosis Isolates from Pulmonary Tuberculosis Patients
... the heterogeneity of Mycobacterium tuberculosis populations and the existence of mixed infections are now generally accepted, systematic studies on their relative importance are ...for heterogeneity and ...
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Heterogeneous response and progression patterns reveal phenotypic heterogeneity of tyrosine kinase inhibitor response in metastatic renal cell carcinoma.
... previously described in ccRCC [1–4]. Hence, it is conceiv- able that molecular alterations that determine treatment responses are unlikely to be encoded by early mutations, called truncal mutations, and that subclonal ...
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Phenotypic heterogeneity in a panel of infectious molecular human immunodeficiency virus type 1 clones derived from a single individual.
... Among the clones tested for their biological characteristics, the three molecular HIV-1 clones derived from time point 2A 1.1, 1.2, and 2.1 and clone 320.3 1 exhibited the most divergent[r] ...
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Description of familial keloids in five pedigrees: evidence for autosomal dominant inheritance and phenotypic heterogeneity
... The present report identified individuals in three families with hypertrophic scars and seven individuals in four fam- ilies with both keloids and hypertrophic scars. Hyper- trophic scars have not been previously ...
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Genetic and phenotypic heterogeneity in familial lecithin: cholesterol acyltransferase (LCAT) deficiency Six newly identified defective alleles further contribute to the structural heterogeneity in this disease
... The presence of lecithin:cholesterol acyltransferase LCAT deficiency in six probands from five families originating from four different countries was confirmed by the absence or near abs[r] ...
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Intrafamilial phenotypic heterogeneity in a Taiwanese family with a MAPT p.R5H mutation: a case report and literature review
... Background: Frontotemporal degeneration (FTD) is a clinically and genetically heterogeneous neurodegenerative disorder characterized by deficits in executive function that frequently overlaps with parkinsonism and motor ...
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BubR1 allelic effects drive phenotypic heterogeneity in mosaic variegated aneuploidy progeria syndrome
... notypic heterogeneity is that the progeroid phenotypes associated with BubR1 mutations are typically not observed in the now large collection of mouse strains with mutations in other key mitotic reg- ulators (27, ...
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Yale School of Public Health Symposium on tissue imaging mass spectrometry : illuminating phenotypic heterogeneity and drug disposition at the molecular level
... ‘ A picture is worth a thousand words ’ is an idiom from the English language ( ‘ borrowed ’ from on old Chinese proverb) that conveys the notion that a complex idea can be succinctly and fully described by a single ...
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