phosphate/pyrophosphate
Alkaline phosphatase: placental and tissue nonspecific isoenzymes hydrolyze phosphoethanolamine, inorganic pyrophosphate, and pyridoxal 5' phosphate Substrate accumulation in carriers of hypophosphatasia corrects during pregnancy
... Hypophosphatasia features selective deficiency of activity of the tissue-nonspecific (liver/bone/kidney) alkaline phosphatase (ALP) isoenzyme (TNSALP); placental and intestinal ALP isoenzyme (PALP and IALP, respectively) ...
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Phosphate/Pyrophosphate and MV-related Proteins in Mineralisation: Discoveries from Mouse Models
... ANK, which is encoded by the mouse progres- sive ankylosis (ank) gene, appears to function as a multiple-pass, transmembrane PPi-channelling pro- tein, allowing PPi molecules to pass through the plasma membrane from the ...
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Basic fibroblast growth factor regulates phosphate/pyrophosphate regulatory genes in stem cells isolated from human exfoliated deciduous teeth
... Addition of 10 ng/ml bFGF to SHEDs during in vitro osteo/odontogenic differentiation decreased ALPL mRNA expression and ALP enzyme activity, increased ANKH mRNA, and decreased both P i /[r] ...
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Pyruvate-Phosphate Dikinase of Oxymonads and Parabasalia and the Evolution of Pyrophosphate-Dependent Glycolysis in Anaerobic Eukaryotes
... tually exclusive and PFK has been shown to have switched phosphate-donor specificity several times (3, 27); thus, PFP originated several times independently. In contrast, the phy- logeny of PPDK is less complex ...
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Pyrophosphate Stimulates the Phosphate-Sodium Symporter of Trypanosoma brucei Acidocalcisomes and Saccharomyces cerevisiae Vacuoles
... Pyrophosphate does not penetrate Xenopus oocytes, but it stimulates the Pho91 transporters that are expressed in them. If this happens through the SPX domain, the domain would have to be oriented toward the ...
10
β-pyrophosphate: A potential biomaterial for dental applications
... washed with pre-warmed PBS and fixed with 100 mM phosphate buffered with 2.5% EM grade Glutaraldehyde for 15 min at 37 C Cells were pelleted, fixative was removed, pellet resuspended and fresh 2.5% Glutaraldehyde ...
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Pyrophosphate Dependent ATP Formation from Acetyl Coenzyme A in Syntrophus aciditrophicus, a New Twist on ATP Formation
... AMP-forming, acetyl-CoA synthetase is expressed and trans- lated under all growth conditions. Enzymes that catalyze impor- tant catabolic functions such as ATP synthesis are expected to be highly expressed at the mRNA ...
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β pyrophosphate : a potential biomaterial for dental applications
... β- pyrophosphate pellets (sintered at 1000 o C) and its mineral precursor (brushite), the wear rate during simulated tooth-brushing trials and the cytocompatibility of these minerals in powder ...
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Extraosseous calcification Evidence for abnormal pyrophosphate metabolism in uremia
... mean pyrophosphate was 11 +/- ...generate pyrophosphate supporting the presence of brushite in these ...of pyrophosphate in apatitic deposits from both uremic and hypercalcemic patients actually ...
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Physicochemical characterization of ferric pyrophosphate citrate
... Ferric pyrophosphate citrate is a new member of the class of iron salts knows as ...ferric pyrophosphate complexes, FPC has improved solubility ( [ 1000 mg/mL) and stability and is the first pharmaceutical ...
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Pyrophosphate analogues as antiviral agents
... of pyrophosphate in the chain-elongation step of the ...pyro phosphate inhibit the enzyme in an analogous manner but that pyrophosphate is the less ...of pyrophosphate in the ...
201
Disease associated particulates and joint inflammation; mechanistic insights and therapeutic targets
... calcium phosphate crystals, gout-associated monoso- dium urate crystals, and calcium deposition disease-associated calcium pyrophosphate crystals, contributes to joint destruction through the production of ...
8
Pyrophosphate: a key inhibitor of mineralisation
... of pyrophosphate from the intra-to-extracellular environment, may also contribute to extracellular pyrophosphate levels ...intracellular pyrophosphate concentration is only in the micromolar range ...
26
Drug loading capacity of microporous β-pyrophosphate crystals
... calcium phosphate minerals have poor electrical conductivity, prior to SEM each sample was coated with a 5 nm thick layer of platinum and then vacuum cleaned for 10 ...
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Radiology of crystal arthropathies
... Among various crystal arthropathies, gout is most common. Conventional radiological findings are typical in some of these crystal arthropathies. Calcium pyrophosphate crystal deposition disease (CPPD) is also ...
5
Fungal Inositol Pyrophosphate IP7 Is Crucial for Metabolic Adaptation to the Host Environment and Pathogenicity
... The environment of the host lung is low in glucose (46), and enzymes involved in the use of alternative carbon sources are es- sential for cryptococcal pathogenicity (47–49). We therefore com- pared the extent of growth ...
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Media optimization for inorganic phosphate solubilizing bacteria isolated from anand argiculture soil
... Phosphorous is second only to nitrogen as an essential macronutrient for plant growth and development (Schefferet al., 1998). Soil is rich in insoluble mineral and organic phosphates but deficient in available ...
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Calcium pyrophosphate crystal deposition disease: diagnosis and treatment
... Calcium pyrophosphate dihydrate crystal deposition disease (CPPD) is an inflammatory arthritis produced by the deposition of calcium pyrophosphate (CPP) crystals in the synovium and periarticular soft ...
9
Thermal Insitu Analyses of Multicomponent Pyrophosphate Cathodes Materials
... The formation of pyrophosphate bonds were confirmed with Fourier transform infrared (FTIR) spectroscopy and the results are presented in Figure 4. The peak at band 738.3 and 909.6 cm -1 belonged to the symmetric ...
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Bone pyrophosphate in uremia and its association with extraosseous calcification
... significant inverse correlation between duration of dialysis and percent bone ash (r = -0.59) (P less than 0.05). A definite relationship existed between elevated bone pyrophosphate levels and soft tissue ...
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