phospholipase D (PLD)
Paxillin and Phospholipase D Interact To Regulate Actin-Based Processes in Dictyostelium discoideum
... and phospholipase D ...40). PLD hydrolyzes phosphatidylcholine, re- sulting in the production of choline and the second messenger phosphatidic acid ...and PLD both regulate the actin ...
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Phospholipase D regulates the size of skeletal muscle cells through the activation of mTOR signaling
... that Phospholipase D (PLD) activates mTOR signaling, through the binding of its product phosphatidic acid (PA) to mTOR ...of PLD on muscle cell size could thus be ...of PLD isoforms in ...
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The Arf-GTPase-Activating Protein Gcs1p Is Essential for Sporulation and Regulates the Phospholipase D Spo14p
... cerevisiae phospholipase D (PLD), is essential for sporulation and mediates synthesis of the new membrane that encompasses the haploid nuclei that arise through meiotic ...divisions. PLD ...
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Similarities in the Induction of Post-Golgi Vesicles by the Vaccinia Virus F13L Protein and Phospholipase D
... because phospholipase D (PLD) regulates the budding of vesicles from trans-Golgi membranes (2, 6, 10, 26, 41, ...with PLD, instead of F13L, in post-Golgi vesicles? Can PLD complement an ...
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PldB, a Putative Phospholipase D Homologue in Dictyostelium discoideum Mediates Quorum Sensing during Development
... putative phospholipase D (PLD) homologue, in quorum ...of PLD- catalyzed phosphatidic acid production, allows cells to bypass the requirement for CMF mediated quorum sensing and aggregate at ...
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Characterisation of the mouse glycosyl phosphatidylinositol-phospholipase D (GPI-PLD) gene
... Glycosylphosphatidylinositol-specific phospholipase D (GPI-PLD) is a serum protein presumed to cleave GPI-anchored proteins on the cell surface. As the initial characterisation of GPI-PLD ...
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Isolation of human eosinophil phospholipase D
... Phospholipase D preferentially contained in human eosinophil polymorphonuclear leukocytes as compared to other leukocytes was isolated by sequential asion and cation exchange chromatography and gel ...by ...
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Comparative analysis of Klebsiella pneumoniae genomes identifies a phospholipase D family protein as a novel virulence factor
... putative phospholipase D proteins in strain ...ase D family proteins have been described as important for host cell invasion, bacterial dissemination and dis- ease progression ...bacterial ...
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Differential Regulation of Saccharomyces cerevisiae Phospholipase D in Sporulation and Sec14-Independent Secretion
... 1998b; Xie et al. 1998), supports Sec14-independent We have previously noted that overexpression of Spo14 secretion indicates that the N terminus is important for during sporulation does not result in a concurrent in- ...
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The Role of Phospholipase D in Modulating the MTOR Signaling Pathway in Polycystic Kidney Disease
... mTOR has been shown to negatively regulate autophagy upon nutrient limitation, which leads to suppressed mTOR pathway activity in many cell types. Therefore, we examined whether combining mTOR and PLD inhibitors ...
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Regulation of phospholipase D and primary granule secretion by P2 purinergic and chemotactic peptide receptor agonists is induced during granulocytic differentiation of HL 60 cells
... significant reduction in FMLP- and ATP-stimulated PLD activity observed in cells pretreated with pertussis toxin. At all stages of differentiation, there was good correlation between the relative efficacies of ATP ...
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The role of glycosylphosphatidylinositol phospholipase D (GPI-PLD) in type one hypersensitivity
... A computer search of the GPI-PLD sequence in the Genbank database revealed homology with integrins. GPI-PLD is the only protein so far identified which contains the sevenfold repeat structure, ...
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Studies on a protein kinase C-phospholipase D-MAPKinase pathway
... TPA-induced PLD activation a catalytic site inhibitor was employed since this is the only class of phorbol ester receptors that are protein ...of PLD by ...independent) PLD activity under these ...of ...
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Human placental inositolphosphoglycans may be released by glycosylphosphatidylinositol-phospholipase D, both present in the syncytial brush border membrane investigation in normal and pre-eclamptic placentae
... Free GPI are glycosylphosphatidylinositol compounds which do not anchor attached proteins. The precursor molecules of IPGs are free GPI. Free GPI have been described in mammalian cells by van’t Hof et al, Baumann et al ...
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Characterisation of PLD activity in real time
... of phospholipase D (PLD) by extracellular signals and consequent phosphatidic acid (PtdOH) generation resulted in activation of the Raf1-MAPK signalling cascade (Rizzo et ...the PLD product ...
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Tuning the oviduct to the anandamide tone
... N-acylphosphatidylethanolamine–selective phospholipase D (NAPE-PLD) and its degradation by fatty acid amide hydrolase (FAAH) in mouse embryos and oviducts creates locally an appropriate “anandamide ...
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A review on the effect of sulphur mustard on gene expression alterations, finding the most important molecular functions using gene set functional enrichment analysis
... The severity of the DNA damage may be so high that it will ultimately lead to cell death.[16] SM can alkylate DNA and forms the cross-link, di-(2-guanin-7-yl-ethyl)-sulfide, and two monoadducts, ...
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The Sac1 phosphoinositide phosphatases in mammals
... Identification of a novel family of nonclassic yeast phosphatidylinositol transfer proteins whose function modulates phospholipase D activity and Sec14p-independent cell growth. Germli[r] ...
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In Utero Alcohol Exposure and the Alteration of Histone Marks in the Developing Fetus: An Epigenetic Phenomenon of Maternal Drinking
... Figure 1. Alcohol metabolism in the body. Following alcohol consumption, most is absorbed by the small intestine and the stomach. Through circulation, alcohol quickly reaches the liver, where it is broken down. Two major ...
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Regulated formation of eicosanoids
... In other words, the PDGF-medi- pase A2 the Ca2+-dependent cytosolic phospholipase ated increase in cellular PGE2 synthesis depends on de cPLA2, the secretory phospholipase sPLA2; or the [r] ...
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