PIPERIDIN-4-ONE
t 3 Benzyl r 2,c 6 bis(4 methoxyphenyl)piperidin 4 one
... The title compound was prepared according to the literature procedure (Noller & Baliah, 1948). A mixture of ammonium acetate (0.1 mol, 7.7 g), redistilled 4-methoxybenzaldehyde (0.2 mol, 24.3 ml) and ...
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Synthesis And Anticancer Screening Of Novel Spiro[Chroman-2,4′- Piperidin]-4-One Derivatives With Apoptosis-Inducing Activity
... A novel series of spiro[chroman-2,4′-piperidin]-4-one derivatives was synthesized and evaluated as cytotoxic agents against three human cancer cell lines; MCF-7 (human breast carcinoma), A2780 (human ...
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(3E,5E) 1 Acryloyl 3,5 bis(2 chlorobenzylidene)piperidin 4 one
... For details and applications of ,-unsaturated ketones, see: Anke et al. (1981); Khodair et al. (1997); El-Subbagh et al. (2000); Al-Obaid et al. (1996); El-Barbary et al. (1994); Rungeler et al. (1999); Dimmock et al. ...
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Adsorption and Quantum Chemical Studies on Piperidin-4-One Derivatives for the Corrosion of Mild Steel in 1 M HCl Medium
... Effect of temperature: The effect of temperature on the corrosion of mild steel in 1 M HCl solution in absence and presence of 3-ethyl-2,6-biquinonyl-piperidin-4-one (CQEP) and ...
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An efficient synthesis of monoarylidene derivatives of pyran-4-one and piperidin-4-one
... In continuation of our investigations into aldol condensation reactions of various homo- and hete- rocyclic ketones [17-19], we have decided to apply our experience to the synthesis of the monoarylidene derivatives of ...
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Kinetic study of Oxidation of n-methyl - 2,6-diphynyl – piperidin-4-one Oxime [NMPO] - effect of varying sodium Per chlorate effect of ionic strength(NaClO4) - 94 %
... PCC and N-methyl -2,6-diphynyl – piperidin-4-One Oxime were prepared , PCC by the method of Corey and Suggs. Then acetic acid was purified. Other reagents such asAnalar samples of Sodium Perchlorate ...
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Reactions of Triacetonamine Part II, Synthesis of Novel Pyrazolo(4,3 c)pyridine Derivatives, and 2 (Piperidin 4 ylidene)hydrazinecarbothioamide Derivatives Derived From 2,2,6,6 Tetramethyl piperidin 4 one for In vitro Anticancer Evaluation
... 2,2,6,6-Tetramethylpiperidin-4-one reacts with 2 moles of aromatic aldehydes and thiosemicarbazide or semicarbazide hydrochloride in different conditions to afford piperidine derivatives 1a-f and ...
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Quantum Chemical Studies on the Corrosion Inhibition of Mild Steel by Piperidin 4 One Derivatives in 1 M H3PO4
... It may be noted that in 1A the ring nitrogen has more electronegative charge [N1 ( −0.552812)] than the car- bonyl oxygen [O7 ( −0.445786)]. But 2,6-diphenylpiperdin-4-one exhibits boat conformation with ...
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Crystal structure of 1′,1′′ dimethyl 4′ (4 cholorophenyl)dispiro[11H indeno[1,2 b]quinoxaline 11,2′ pyrrolidine 3′,3′′ piperidin] 4′′ one
... Data collection: APEX2 Bruker, 2004; cell refinement: SAINT Bruker, 2004; data reduction: SAINT; programs used to solve structure: SHELXS97 Sheldrick, 2008; programs used to refine struc[r] ...
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A Comprehensive Account of Spectral, NLO,NBO Analysis, Hartreefock and Density Functional Theory Studies of 1-Methyl 2, 6-Diphenyl Piperidin-4-One
... The extensive vibrational analysis of 1-Methyl 2,6-diphenyl pipeidin4-one performed by HF and DFT methods with 6-311++G (d, p)basis sets. A good correlation was found between the theoretical and experimental wave ...
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Synthesis and Antimicrobial Activity of Piperidin-4-one Derivatives
... The present work to investigate the newer antibacterial and antifungal Agents with less side effect and potent activity.In the present work, a series of 2,6-diaryl-3-methyl-4-piperidones were synthesized by ...
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(3E,5E) 1 Allyl 3,5 bis(4 methoxybenzylidene)piperidin 4 one
... between one of the ortho-H atoms in the aryl ring and the equatorial H atoms at the 2- and 6- positions of the piperidone ring (H5A/H9A or H9B and H15A/H10A or ...
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1 Benzyl 3,5 bis[(E) 3 thienylmethylidene]piperidin 4 one
... conformation with the benzyl substituent in an equatorial position. The sum of the bond angles around N1 [328.38 (13)°] indicates a pyramidal geometry. The N1 atom deviates by 0.715 (2) Å from the least-squares plane ...
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1′,1′′ Dimethyl 4′ phenyldispiro[11H indeno[1,2 b]quinoxaline 11,2′ pyrrolidine 3′,3′′ piperidin] 4′′ one
... A mixture of 1-methyl-3-[E-phenylmethylidene]tetrahydro-2(1H)-pyridinone (1 mmol), ninhydrin (1 mmol), o-phenyl- enediamine (1 mmol) and sarcosine (1 mmol) in methanol was refluxed for 3-4 h. After completion of ...
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Crystal structure of 3 methyl 2,6 bis(4 methyl 1,3 thiazol 5 yl)piperidin 4 one
... C1 0.0485 (12) 0.0321 (11) 0.0387 (12) 0.0025 (9) −0.0018 (9) −0.0007 (9) C2 0.0679 (15) 0.0339 (11) 0.0464 (14) −0.0065 (11) −0.0023 (11) 0.0072 (10) C3 0.0467 (12) 0.0337 (12) 0.0537 (14) −0.0044 (9) 0.0014 (10) ...
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1′,1′′ Dimethyl 4′ (4 methylphenyl)dispiro[11H indeno[1,2 b]quinoxaline 11,2′ pyrrolidine 3′,3′′ piperidin] 4′′ one
... Data collection: APEX2 Bruker, 2004; cell refinement: SAINT Bruker, 2004; data reduction: SAINT; programs used to solve structure: SHELXS97 Sheldrick, 2008; programs used to refine struc[r] ...
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Synthesis, Characterization and Antibacterial Studies on Copper(Ii) Binuclear Complexes with Substituted Piperidin-4-Ones
... ligands are found to be missing in the spectra of the corresponding complexes. The absence of these bands reveals that there may be a conformational change of piperidin-4-one ring due to its ...
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N (2 {[5 Bromo 2 (piperidin 1 yl)pyrimidin 4 yl]sulfanyl} 4 methoxyphenyl)benzenesulfonamide
... C14B 0.048 (2) 0.0373 (19) 0.068 (3) −0.0122 (18) −0.0253 (19) −0.0123 (17) C16B 0.149 (6) 0.198 (7) 0.106 (5) −0.069 (5) −0.017 (4) −0.073 (5) C17B 0.0405 (19) 0.045 (2) 0.047 (2) −0.0164 (17) −0.0120 (16) ...
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A REVIEW ON THE SYNTHESIS AND BIOLOGICAL ACTIVITIES OF PIPERIDIN 4 ONES K P Greeshma * and S Muthulingam
... Ethyl acetoacetate and ethyllevulinate have also been employed as the ketone component for the synthesis of piperidine-4-ones (Scheme 7a) 13, 31-34 . With ethyl acetoacetate, aromatic aldehyde gave ...
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2 Amino 6 (piperidin 1 yl) 4 p tolylpyridine 3,5 dicarbonitrile
... Initially a mixture of 4–methylbenzaldehyde (2 mmol, 0.24 g), malononitrile (3 mmol, 0.198 g), piperidine (1.5 mmol, 0.128 g) and was stirred without any solvent at room temperature. A solid appeared immediately ...
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