placebo-controlled
Randomized, Placebo Controlled Trial of Transdermal Rivastigmine for the Treatment of Encephalopathy in Liver Cirrhosis (TREC Trial)
... randomized, placebo-controlled pilot study demonstrates that transdermal rivastigmine used offlabel with concomitant lactuloseis is safe and effective for improving cognitive function in patients with ...
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A placebo controlled trial of Korean red ginseng extract for preventing Influenza like illness in healthy adults
... Methods/Design: We will conduct a randomized, double-blind, placebo-controlled study at the onset of the influenza seasons. A total of 100 subjects 30-70 years of age will be recruited from the general ...
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Diuretic versus placebo in normotensive acute pulmonary embolism with right ventricular enlargement and injury: a double-blind randomised placebo controlled study. Protocol of the DiPER study
... double-blind, placebo controlled study assessing the superiority of furosemide as compared with placebo in normotensive patients with confirmed acute PE and RV dilation (diagnosed on echocardiography ...
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Compensatory changes in energy balance during dapagliflozin treatment in type 2 diabetes mellitus: a randomised double-blind, placebo-controlled, cross-over trial (ENERGIZE)—study protocol
... double-blind, placebo-controlled crossover study, we aim to study the compensatory changes in energy intake, eating behaviour and energy expenditure accompanying use of the SGLT2 ...
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Duloxetine versus placebo for the treatment of women with stress predominant urinary incontinence in Taiwan: a double-blind, randomized, placebo-controlled trial
... Non-pregnant women 20 years of age and older with pre- dominant symptoms of SUI, were enrolled in this double- blind, randomized, parallel, placebo-controlled, clinical trial conducted at 9 study centers in ...
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A role of Yueju in fast-onset antidepressant action on major depressive disorder and serum BDNF expression: a randomly double-blind, fluoxetine-adjunct, placebo-controlled, pilot clinical study
... double-blinded, placebo-controlled, and randomized pilot clinical trial. Fluoxetine, a well documented late-onset SSRI, was used in adjunct with Yueju or placebo. BDNF levels in the serum before and ...
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Does different information disclosure on placebo control affect blinding and trial outcomes? A case study of participant information leaflets of randomized placebo-controlled trials of acupuncture
... from placebo acu- ...detecting placebo acupuncture presented conflicting results [37, ...of placebo acupuncture, is partly ex- plained in our BI ...the placebo acupuncture group from DD/MI ...
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Randomized, double-blind, placebo-controlled and active-controlled study to assess the relative abuse potential of oxycodone HCl-niacin tablets compared with oxycodone alone in nondependent, recreational opioid users
... between placebo and oxycodone HCl immediate-release 40 mg on drug ...by placebo on study day 3, or vice ...between placebo and immediate-release oxycodone HCl for at least one time point during the 2 ...
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A randomized, double blind, placebo controlled trial to assess the efficacy of topiramate in the treatment of post traumatic stress disorder
... randomized controlled medication trials for PTSD (4597 ...to placebo was seen in ...the placebo group (95% CI – ...to placebo in reducing the sever- ity of the three symptom clusters of PTSD, ...
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<p>Buprenorphine/samidorphan combination for the adjunctive treatment of major depressive disorder: results of a phase III clinical trial (FORWARD-3)</p>
... short-term placebo-controlled ...the placebo run-in design may have delivered positive-efficacy results if more studies with this design had been ...
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Long-term safety of biologics in the treatment of psoriasis
... the placebo-controlled phases of the anti- IL-12/23 studies, 10 of 3179 patients receiving anti-IL-12/23 therapies experienced MACE compared with zero events in 1474 patients receiving ...
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Two Phase II randomized trials on the CRTh2 antagonist AZD1981 in adults with asthma
... double-blind, placebo-controlled, parallel dose-range finding study to assess the efficacy and tolerability of AZD1981 in patients with asthma inadequately controlled on existing ICS (protocol ...
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Hepatocellular carcinoma: current trends in worldwide epidemiology, risk factors, diagnosis, and therapeutics
... randomized, placebo-controlled trial com- paring TACE plus placebo versus TACE plus sorafenib for intermediate stage HCC with Child–Pugh class A cirrhosis (SPACE [Sorafenib or Placebo in ...
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Biologics in the treatment of psoriasis and emerging new therapies in the pipeline
... The long-term effects of ustekinumab remain unknown, and much information will stem from post-marketing surveillance and additional long-term studies. Cumulative safety experience was analyzed through the pooling of ...
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Placebo-only-controlled versus active-controlled trials of new drugs for nine common life-threatening diseases
... of placebo- only versus active control groups in clinical trials supporting FDA drug or biological product approvals for nine common life-threatening diseases, we determined that over a third of trials included ...
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The ethics of using placebo in randomised controlled trials: a case study of a Plasmodium vivax antirelapse trial
... of placebo ar- gued that placebo or “standard of care” arms were per- missible, and in fact imperative due to the unavailability of a proven treatment [3, ...a placebo-controlled trial would ...
5
Safety and efficacy of PG102P for the control of pruritus in patients undergoing hemodialysis (SNUG trial): study protocol for a randomized controlled trial
... This is a multicenter, randomized, double-blind, placebo- controlled trial in which one group will be treated with PG102P (1.5 g/day) and the other with a placebo. It is an investigator-initiated ...
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Everolimus in the treatment of subependymal giant cell astrocytomas, angiomyolipomas, and pulmonary and skin lesions associated with tuberous sclerosis complex
... double-blind, placebo-controlled—A Randomized, Double-blind, Pla- cebo-controlled Study of RAD0001 in the Treatment of Angiomyolipoma in Patients With Either Inberous Sclerusis Complex (TSC) or ...
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Differential Effects of Estradiol and Progesterone on Cardiovascular Risk Factors in Postmenopausal Women
... In this placebo-controlled, prospectively randomized, and doubly masked study, we in- vestigated the separate and combined effects of parenteral E 2 , natural P, and/or placebo on lipids[r] ...
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Potential role of gabapentin and extended- release gabapentin in the management of menopausal hot flashes
... double-blind, placebo-controlled clinical trial in 214 men with hot flashes who were on an androgen-deprivation therapy program for prostate ...groups: placebo; gabapentin, 300 mg/day; gabapen- tin, ...
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