Plasminogen Activator Inhibitor
The effects of residual platelets in plasma on plasminogen activator inhibitor-1 and plasminogen activator inhibitor-1-related assays
... degradation). Plasminogen activator inhibitor-1 activ- ity, plasminogen activator inhibitor-1 antigen, tissue plasminogen activator/plasminogen ...
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Plasminogen activator inhibitor-1 and cardiovascular risk
... 2.1.3.1. Plasminogen activator inhibitor-1 activity PAI-1 is a plasma protein that rapidly and specifically inhibits t-PA and ...and plasminogen activator binding proteins, and have ...
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Plasminogen activator inhibitor type 1 deficiency
... Plasminogen activator inhibitor, type 1 deficiency is a rare bleeding disorder whose mainstay of treatment is antifibrinolytic agents. The accurate diagnosis of this disorder remains a challenge and ...
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Association of plasminogen activator inhibitor-1 and tissue plasminogen activator with type 2 diabetes and metabolic syndrome in Malaysian subjects
... The plasminogen activator inhibitor-1 -675 4G/5G genotype influences the risk of myocardial infarction associated with elevated plasma proinsulin and insulin concentrations in men from Europe: the ...
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Association of plasminogen activator inhibitor 1 and tissue plasminogen activator with type 2 diabetes and metabolic syndrome in Malaysian subjects
... The plasminogen activator inhibitor-1 -675 4G/5G genotype influences the risk of myocardial infarction associated with elevated plasma proinsulin and insulin concentrations in men from Europe: the ...
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Role of urokinase plasminogen activator and plasminogen activator inhibitor mRNA expression as prognostic factors in molecular subtypes of breast cancer
... nase plasminogen activator (uPA) and plasminogen activator inhibitor-1 (PAI-1) in fresh-frozen tumor tissue from primary breast cancers by a commercially ...
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Effects of pitavastatin on plasminogen activator inhibitor-1 in hyperlipidemic patients
... Notes: Bars are shown as mean ± SD. *Student’s t-test (before versus after pitavastatin treatment); **ANOVA analysis (reponders versus nonresponders). Abbreviations: LDL-C, low-density lipoprotein cholesterol; BMI, body ...
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Picornavirus Receptor Down-Regulation by Plasminogen Activator Inhibitor Type 2
... protease inhibitor (serpin), plasminogen activator inhibitor type 2 (PAI-2), affords a high level of protection from lytic infection by multiple human ...
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Possible Role of Plasminogen Activator Inhibitor-1 in Childhood Bronchial Asthma
... Background: Plasminogen activator inhibitor (PAI)-1 is the main inhibitor of the fibrinolytic system and is known to play an essential role in tissue ...plasma activator ...
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Plasminogen activator inhibitor 1 in acute hyperoxic mouse lung injury
... Abstract Hyperoxia-induced lung disease is associated with promi- nent intraalveolar fibrin deposition. Fibrin turnover is tightly regulated by the concerted action of proteases and antipro- teases, and inhibition of ...
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Thrombin induction of plasminogen activator inhibitor in cultured human endothelial cells
... We have examined the effect of thrombin on the activity of plasminogen activator (PA) and plasminogen activator-inhibitor (PA-I) in medium conditioned by primary cultures of human umbili[r] ...
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Usefulness of plasminogen activator inhibitor-1 as a predictive marker of mortality in sepsis
... complex, plasminogen activator inhibitor-1, and protein C activity for early identification of severe coagulopathy in initial phase of sepsis: a prospective observational ...
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The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans
... tissue plasminogen activator: plasminogen activator inhibitor-1 complex and matrix metalloproteinase-3 are significantly ele- vated in cerebrospinal fluid of trauma patients and ...
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Close relationship of tissue plasminogen activator plasminogen activator inhibitor 1 complex with multiple organ dysfunction syndrome investigated by means of the artificial pancreas
... ‡ Department of Emergency and Critical Care Medicine, Chiba University School of Medicine, Chuo-ku, Chiba-shi, Chiba, Japan Correspondence: Masami Hoshino, Department of Intensive and Critical Care Medicine, Tokyo Police ...
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Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease
... 18. Tofler GH, Massaro J, O'Donnell CJ, Wilson PW, Vasan RS, Sutherland PA, Meigs JB, Levy D, D'Agostino RB, Sr. Plasminogen activator inhibitor and the risk of cardiovascular disease: The framingham ...
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Peptide mediated inactivation of recombinant and platelet plasminogen activator inhibitor 1 in vitro
... https://doi.org/10.1172/JCI117937. Plasminogen activator inhibitor-1 (PAI-1), the primary inhibitor of tissue-type plasminogen activator (t-PA) and urokinase plasminogen ...
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Development and optimization of the methods for determining activity of plasminogen activator inhibitor-1 in plasma
... (plasminogen activator inhibitor, РАІ-1), поскольку его количество в плазме воз- растает при остром инфаркте миокарда, зло- качественных новообразованиях, сахарном диабете и ...
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Plasminogen activator inhibitor type 1 regulates microglial motility and phagocytic activity
... Indirect ELISA for plasminogen activator inhibitor type 1 Indirect ELISA was used for the recombinant mouse PAI-1 protein measurements. Cells were treated with a combination of LPS (100 ng/ml) and ...
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Coordinated induction of plasminogen activator inhibitor 1 (PAI 1) and inhibition of plasminogen activator gene expression by hypoxia promotes pulmonary vascular fibrin deposition
... of plasminogen activator inhibitor-1 (PAI-1) antigen, detected by ELISA, increased in a time- dependent fashion after hypoxic exposure (increased as early as 4 h, P < ...tissue-type ...
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Coagulopathy After Cardiac Surgery May Be Influenced by a Functional Plasminogen Activator Inhibitor Polymorphism
... of plasminogen activator inhibitor-1 (PAI-1) gene expression after cardiac surgery and its relation with PAI genotype, and obtained preliminary data regarding its relation to perioperative ...
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