platelet-adhesion
P-selectin-mediated platelet adhesion promotes tumor growth
... P-selectin-mediated platelet adhesion in solid tumors using the Rip1-Tag2 mouse model and xenograft tumor ...abolishes platelet deposition within solid ...activates platelet integrins via the ...
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Biochemical and biophysical aspects of human platelet adhesion to collagen fibers
... negligible adhesion (at the platelet concentrations employed) in contrast to washed platelets suspended in ...the adhesion of washed ...muramidase. Platelet adhesion is proportional to ...
11
Human Cytomegalovirus Infection of Endothelial Cells Triggers Platelet Adhesion and Aggregation
... 1, platelet adhesion appears to be mediated by HSV type 1 glycoprotein C, which can bind to and activate coagulation factor X, leading to thrombin genera- tion and platelet adhesion ...
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Fibrinogen independent platelet adhesion and thrombus formation on subendothelium mediated by glycoprotein IIb IIIa complex at high shear rate
... Platelet adhesion and thrombus formation on subendothelium, studied at a shear rate of 2,600 s-1, were inhibited by two synthetic peptides known to interact with ...Neither platelet adhesion ...
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Thrombin stimulates tumor platelet adhesion in vitro and metastasis in vivo
... the platelet GPIIb-GPIIIa integrin: monoclonal antibody 10E5, tetrapeptide RGDS and gamma chain fibrinogen decapeptide LGGAKQAGDV, as well as polyclonal antibodies against the platelet adhesive ligands, ...
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Heparanase expression upregulates platelet adhesion activity and thrombogenicity
... stronger adhesion activity as compared to Ctr platelets, likely contributing to a higher thrombotic activity in a carotid thrombosis ...the platelet heparanase to hyper-thrombotic conditions often seen in ...
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ARTEMISIA DRACUNCULUS, PUNICA GRANATUM AND BERBERIS VULGARIS INHIBITORY EFFECTS ON PLATELET ADHESION AND COAGULATION FACTORS IN RATS
... The exposed PS accelerates the prothrombinase complex reactions of the coagulation cascade, leading to the creation of thrombin, the most potent platelet agonist (5,6). Thrombin, in turn, activates different ...
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A novel method for the measurement of flow induced platelet activation at nanoscale resolution level
... study platelet activation (Fritz, Radmacher et ...investigate platelet adhesion to these surfaces (Karagkiozaki, Logothetidis et ...and adhesion contact areas between the adjacent platelets ...
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Influenza Virus Infection Induces Platelet-Endothelial Adhesion Which Contributes to Lung Injury
... induces platelet-endothelial ...influenza-induced platelet-endothelial interactions (n ⫽ 3; *, P ⬍ ...induce platelet-endothelial interaction, as the effect was not recapitulated by treatment with ...
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P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries
... in platelet thrombosis and how its complete absence affects the thrombotic ...aspirin. Platelet adhesion to vWF was impaired in P2Y 12 –/– ...While adhesion to fibrinogen and collagen appeared ...
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Thrombus formation and platelet vessel wall interaction in the nephrotic syndrome under flow conditions
... vitro platelet aggregability and hypercoagulability are generally held to be main determinants in the prethrombotic state in ...increase platelet-vessel wall ...normal platelet adhesion and ...
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NH2+ implantations induced superior hemocompatibility of carbon nanotubes
... The platelet adhesion rate of a material can be calculated as follows: Platelet adhesion rate ð Þ ¼ % AB A 100% , where A is the total number of platelets, and B is the number of platelets ...
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Thrombospondin induced adhesion of human platelets
... inhibited adhesion by 40- ...inhibited platelet adhesion of both normal and thrombasthenic platelets by ...collagen-induced platelet adhesion, but had no effect on fibronectin-induced ...
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Original Article Exogenous carbon monoxide suppresses LPS-stimulated platelet activation by Interfering with the TLR4/PKCα/integrin α
... of platelet adhesion and aggregation was significantly increased with LPS stimula- tion, and treatment with CORM-2 effectively Figure ...1. Platelet adhesion, aggregation and granule ...
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Platelet interaction with rabbit subendothelium in von Willebrand's disease: altered thrombus formation distinct from defective platelet adhesion
... resultant platelet and fibrin interaction was quantified by the use of several morphometric techniques, one of which was developed to measure more precisely the dimensions (height and volume) of platelet ...
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Static platelet adhesion, flow cytometry and serum TXB2 levels for monitoring platelet inhibiting treatment with ASA and clopidogrel in coronary artery disease: a randomised cross over study
... static platelet adhesion that have been used in previous studies aimed at investigating treatment effects of platelet inhibiting ...static platelet adhesion assay is reproducible over ...
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Platelet Adhesion and Degranulation Induce Pro Survival and Pro Angiogenic Signalling in Ovarian Cancer Cells
... 100 ng of total RNA extracted from control cells and cells exposed to washed platelets/platelet releasate was labelled using the Ambion WT Expression kit [Ambion/Life Technologies, Austin, TX, USA] including the ...
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Mice lacking the signaling molecule CalDAG GEFI represent a model for leukocyte adhesion deficiency type III
... exhibited strong defects in Rap1 and b 1 and b 2 integrin activation while maintaining normal calcium flux, degranulation, and ROS generation. Neutrophils from CalDAG-GEFI–deficient mice failed to adhere firmly to ...
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Human cytotrophoblasts adopt a vascular phenotype as they differentiate A strategy for successful endovascular invasion?
... their adhesion receptor phenotype so as to resemble the endothelial cells they re- ...let-endothelial adhesion molecule-1, vascular endothelial adhesion molecule-1, and a ...
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Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation
... between platelet- and vessel wall–derived PDI, we induced massive thrombocytopenia by targeting platelet GPIbα with an antibody mixture that suppresses platelet counts by more than 95% ...
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