Platelet-Derived Endothelial Cell Growth Factor
Angiogenic biomarkers in children with congenital heart disease: possible implications
... Angiogenic growth factors are so called because of their varying ability to induce the proliferation of various cells in vitro, which contribute to the process of angio- genesis in vivo ...Vascular ...
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Growth factor expression in aorta of normotensive and hypertensive rats
... of platelet-derived growth factor (PDGF) B chain and PDGF A chain, insulin-like growth factor (IGF)-I and IGF-II, endothelial cell growth factor ...
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Genetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease
... cyst growth in nonorthologous models and Pkd1 heterozygous mice (127, 131), and a phase II clinical trial is currently ongoing ...vascular endothelial growth factor receptor and ...
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Metabolic syndrome and the skin: a more than superficial association. Reviewing the association between skin diseases and metabolic syndrome and a clinical decision algorithm for high risk patients
... stimulating factor; TNF‑α: tumor necrosis factor‑4 α; VEGF: vascular endothelial growth factor; PDGF‑BB: BB isoform of the platelet derived 5 growth factor; ...
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Evaluation of effectiveness of concentrated growth factor on osseointegration
... many growth factors such as bone morphogenetic protein (BMP), platelet-derived growth factor (PDGF), insulin-like growth factor (IGF), vascular endothelial ...
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Structural optimization and evaluation of novel 2-pyrrolidone-fused (2-oxoindolin-3-ylidene)methylpyrrole derivatives as potential VEGFR-2/PDGFRβ inhibitors
... epidermal growth factor; FGF: fibroblast growth factor; VEGF: vascular endothelial growth factor; PDGF: platelet‑derived growth factor; RCC: ...
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Caries Induced FGF 2 Expression in Human Dental Pulp
... regulatory factor in the control of vascular permeability and angiogenesis (Ferrara et ...Vascular endothelial growth factor is originally a basic 45-kDa heparin-binding ...the ...
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Pazopanib in advanced desmoplastic small round cell tumours: a multi-institutional experience
... cular endothelial growth factor receptors (VEGFR) 1 – 3, c-KIT, and the platelet-derived growth factor receptors (PDGFR) alpha and beta ...clear cell renal ...
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Antiangiogenic effects in patients with progressive desmoplastic small round cell tumor: data from the French national registry dedicated to the use of off-labeled targeted therapy in sarcoma (OUTC’s)
... vascular endothelial growth factor receptors (VEGFR) 1–3, c-KIT, and the platelet-derived growth factor receptors (PDGFR) alpha and beta, and has been approved for ...
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Platelet-derived growth factor regulates the secretion of extracellular vesicles by adipose mesenchymal stem cells and enhances their angiogenic potential
... by cell stimulation indicates that packing of mediators within EVs is a regulated ...vascular endothelial cells [53] and plays an important role in the amplification and mobilization of progenitor ...
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Regional expression of the platelet derived growth factor and its receptors in a primate graft model of vessel wall assembly
... Healing baboon polytetrafluoroethylene grafts express PDGF mRNA in the neointima. Perfusates of graft segments also contain PDGF-like mitogenic activity. To extend these findings, we studied the expression and regional ...
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Platelet-rich plasma stimulates angiogenesis in mice which may promote hair growth
... various growth factors, including platelet-derived growth fac- tor (PDGF), vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), ...
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Molecular and clinical significance of fibroblast growth factor 2 (FGF2 /bFGF) in malignancies of solid and hematological cancers for personalized therapies
... More recently, second-generation inhibitors targeting FGFRs with high selectivity have been developed (Table 5, Figure 4). For example, Debio 1347, developed by Debiopharm Group, a Swiss-based global biopharmaceutical ...
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PDGF/PDGFR effects in osteosarcoma and the “add-on” strategy
... Although synergistic antiproliferative effects of PDGF/ PDGFR inhibitors, such as imatinib and olaratumab, and classical cytotoxic agents (i.e., AMD, cisplatin) were observed in both in vitro and in vivo experiments, the ...
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<p>Umbilical Cord-Derived Mesenchymal Stem Cell-Derived Exosomes Combined Pluronic F127 Hydrogel Promote Chronic Diabetic Wound Healing and Complete Skin Regeneration</p>
... with endothelial cell proliferation and is followed by migration, adhesion, and ...57 Cell proliferation and migra- tion are two key processes in angiogenesis and were found signi fi cantly increased ...
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Platelet derived growth factor inhibits bone regeneration induced by osteogenin, a bone morphogenetic protein, in rat craniotomy defects
... Platelet-derived growth factor (PDGF) is a potent moderator of soft tissue repair through induction of the inflammatory phase of repair and subsequent enhanced collagen ...
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Efficient differentiation of human embryonic stem cells to arterial and venous endothelial cells under feeder- and serum-free conditions
... trophic growth factors, known as angiocrine fac- tors, which lead to proliferation and migration of ECs from pre-existing blood ...assess cell migration, in vitro wound closing assays were performed over a ...
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Polysialic acid is released by human umbilical vein endothelial cells (HUVEC) in vitro
... Degradation of polySia supports the migration of HUVEC To test, whether polySia modulates the cellular migra- tion of HUVEC, in vitro scratch assays were applied to confluent cell monolayers [30, 33]. Following ...
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Original Article The overexpression of PDGF-BB and its receptor is correlated with lymphatic metastasis in patients with non-small cell lung cancer
... stromal-derived factor- 1alpha/CXCR4 axis upon binding to its specific receptor, thus activating endothelial cells as an angiogenesis factor ...independent factor for the prognosis of ...
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Growth factors in idiopathic pulmonary fibrosis: relative roles
... Immunohistochemical studies in patients with IPF reveal enhanced expression of TGF-β1 in a number of cell types. In early disease with minimal fibrosis, this was found pri- marily in alveolar macrophages. In ...
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