platelet-derived growth factor-β
Molecular mechanisms underlying therapeutic potential of pericytes
... 1): platelet-derived growth factor receptor β (PDGFRβ): re- ceptor with tyrosin kinase activity, involved in pericytes proliferation and recruitment [11]; nerve-glial antigen-2 (NG2): ...
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Immunolocalization of platelet‐derived growth factor receptor‐β (PDGFR‐β) and pericytes in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)
... transforming growth factor-β, angiopoietin and platelet-derived growth factor (PDGF) ...receptor- β (PDGFR- β ) to the capillary wall during vessel ...
14
Efficacy of a New Autologus Platelet Gel: in Vitro Study
... as Growth Factors (GFs) (6). Platelet growth factors are responsible for the primary migration of cells to the injured site and the triggering of proliferation of these cells once at the location ...
6
Inhibition of Bone Marrow-Derived Mesenchymal Stem Cells Homing Towards Triple-Negative Breast Cancer Microenvironment Using an Anti-PDGFRβ Aptamer
... against platelet-derived growth factor receptor β (PDGFRβ) causes the inhibition of receptor-dependent signaling pathways thus drastically hampering BM-MSC recruitment towards TNBC cell ...
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Safety study: is there a pathologic IGF-1, PDGF and TGF-ß cytokine expression caused by adjunct BMP-7 in tibial and femoral non-union therapy?
... like growth factor 1 (IGF-1), platelet-derived growth factor AB (PDGF-AB) and transforming growth factor beta (TGF-β) were compared between patients with the ...
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Neovascular age-related macular degeneration: intraocular inflammatory cytokines in the poor responder to ranibizumab treatment
... cytokine/Angiogenesis/Growth factor and a Cardiovascular Magnetic Bead Panel Immunology Multiplex assay (EMD Millipore, Billerica, MA, ...IL-17A, platelet-derived growth ...
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Effect of recombinant PDGF-BB on bone formation in the presence of β-tricalcium phosphate and bovine bone mineral matrix: a pilot study in rat calvarial defects
... binant platelet-derived growth factor-BB (PDGF-BB) can support the process of bone formation, presumably by serving as a mitogen and chemoattractant for mesenchy- mal cells and by stimulating ...
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Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: a new potential target for antifibrotic therapy
... tumor growth and angiogenesis in nu- merous cancer types ...including platelet-derived growth factor BB (PDGF-BB), trans- forming growth factor-β (TGF-β), ...
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Evaluation of effectiveness of concentrated growth factor on osseointegration
... many growth factors such as bone morphogenetic protein (BMP), platelet-derived growth factor (PDGF), insulin-like growth factor (IGF), vascular endothelial growth ...
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Original Article The overexpression of PDGF-BB and its receptor is correlated with lymphatic metastasis in patients with non-small cell lung cancer
... prognostic factor for human ...multiple growth factors. Platelet-derived growth factor-BB (PDGF-BB) and platelet-derived growth factor ...
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The role of angiogenic factors in predicting clinical outcome in severe bacterial infection in Malawian children
... endothelial growth factor (VEGF), a dimeric 46-kDa gly- coprotein, is an endothelial cell-specific, multifunctional ...[6,7]. Platelet-derived growth factor (PDGF) has angiogenic ...
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CSF evidence of pericyte damage in Alzheimer’s disease is associated with markers of blood-brain barrier dysfunction and disease pathology
... CSF and serum sPDGFRβ levels were measured by sand- wich ELISA (Invitrogen Cat no EHPDGFRB, Thermo Fisher Scientific, Loughborough, UK). CSF samples (100 μL undiluted) and serum (diluted 1 in 40 in propri- etary dilution ...
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Structural optimization and evaluation of novel 2-pyrrolidone-fused (2-oxoindolin-3-ylidene)methylpyrrole derivatives as potential VEGFR-2/PDGFRβ inhibitors
... epidermal growth factor; FGF: fibroblast growth factor; VEGF: vascular endothelial growth factor; PDGF: platelet‑derived growth factor; RCC: renal ...
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Effects of platelet derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat storing cells
... of growth curves revealed a similar pattern of potency of the growth ...other growth factors together with PDGF by inflammatory cells represents a potent potential stimulus for FSC proliferation in ...
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Molecular and clinical significance of fibroblast growth factor 2 (FGF2 /bFGF) in malignancies of solid and hematological cancers for personalized therapies
... endothelial growth factor (VEGF) signaling, whereby FGF-induced signaling promotes resistance to VEGF receptor signaling for blocking of the VEGF ...
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Evidence for the use of ultrasound therapy for the management of mandibular osteoradionecrosis
... Almost simultaneously with the appearance of an ultrastructuraly detectable basal lamina, pericytes establish contact with endothelial cells in the sprout (Paku and Paweletz, 1991). Pericyte arrival also occurs prior to ...
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Receptor tyrosine kinases: Characterisation, mechanism of action and therapeutic interests for bone cancers
... cell growth, proliferation, survival, and motility, and also regulate the epithelial – mesenchymal transi- tion (EMT) with a strong impact on the development of metas- ...
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Platelet Rich Plasma Intra Articular Injection for Chronic Synovitis Treatment in Patients with Haemophilia One Year Follow Up
... with inhibitors, an initial dose of recombinant FVIIa (rFVIIa) 150- 200μg/kg immediately before the injection was infused, followed by three doses of 90μg/kg every 3 hours. Then, a high daily dose (200-300μg/kg) was ...
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Fat extract promotes angiogenesis in a murine model of limb ischemia: a novel cell-free therapeutic strategy
... hepatocyte growth factor (HGF), granulocyte – macrophage colony-stimulating factor (GM-CSF), trans- forming growth factor beta (TGF- β ), and insulin-like growth ...
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Expressions of Growth Factors in Autologous Derived Platelet-Rich Plasma and Platelet-Poor Plasma; Implication for Tissue Reparation and Wound Healing
... the platelet count from the PRP were weak, this might be due to small sample size, or might be due to isolated incidents of inefficient concentration of ...the platelet concentration process is reliable by ...
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