PLATINUM(II) COMPLEX
Trypan Blue Exclusion Assay Verifies in Vitro Cytotoxicity of New Cis-Platinum (II) Complex in Human Cells
... many platinum(II) complexes have been synthesized and ...a platinum (II) complex, which used the quinoline amine as a ligand, with an objective of finding a compound that displays ...
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Antitumor and Antioxidant Activities of a Novel Platinum(II)-PyrazineCarboxamide Complex Against Ehrlich Ascites Carcinoma Induced in Mice
... of platinum(II)-pyrazinecarboxamide- bipyridine complex (PCABpy-Pt) against Ehrlich ascites carcinoma (EAC) cells induced in ...weeks), platinum complex group (mice were ...PCABpy-Pt ...
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A cytostatic ruthenium(II)-platinum(II) bis(terpyridyl) anticancer complex that blocks entry into S phase by up-regulating p27KIP1
... Ru II -Pt II binuclear terpyrine- derived complex, VR54 (Scheme 1), where the ditopic ligand tpypma (tpypma = 4-([2,2':6',2''-terpyridine]-4'-yl)-N-(pyridin-2- ylmethyl)aniline) allows an octahedral ...
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Hexanuclear Complex of Platinum(II) with Cleavage Product of Cystamine Dihydrochloride by β Mercaptoethylamine
... of Platinum(II) and has been showed under these conditions in cystamine cleavage of sulfur- sulfur bond occurring with subsequent formation of the deprotonated β ...with Platinum(II) atoms, it ...
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Tryptophan switch for a photoactivated platinum anticancer complex
... known as a mediator of electron transfer between distant electron acceptor/donor centers in proteins, and such properties may make the free amino acid clinically useful for controlling the activity of ...
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Photodynamic killing of cancer cells by a Platinum(II) complex with cyclometallating ligand
... of complex 1 to bind DNA in cells. Cells were incu- bated with complex 1 for 30 min, chromosome metaphase spreads were prepared and imaged using multiphoton excitation (λ ex = 780 nm) ...with complex ...
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Advances in Platinum Complex Cancer Chemotherapy178-184
... It is over twenty years since cisplatin was first given to cancer patients, and a decade since the initiation of clinical trials of carboplatin.. Nevertheless, platinum-based c[r] ...
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Mechanisms of C H Bond Activation by Platinum(II)
... [(N–N)Pt II (H)(alkene)] + ...σ complex, (b) oxidative cleavage to a 5-coordinate [Pt IV (methyl)(alkyl)(hydride)] intermediate, (c) reductive coupling to afford a methane C–H σ complex, (d), ...
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Electrochemical Immunosensor Based on the Interactions Between Polypyrrole and Cobalt (II) Salicylaldiimine Dendrimer
... Polyrrole composites formed with cobalt (II) SDD complex on platinum electrodes showed good recognition and transduction properties for label-free anti-tTG antibody immunosensors. These composites ...
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Synthesis andRreactivity of Copper(I), Copper(II), Platinum(II) and Platinum(IV) Complexes with Non-dative Heteroatomic Ligands
... pharmaceutical products, nine contain one or more chiral centers where at least one of the substituents is not carbon, which underscores the importance of enantioselective C-X bond formation (X = N or O). 5 Thus, ...
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Platinum(II) catalyzed diene cyclizations
... electrophilic complex to enable rapid β -H elimination and provide 1 at ...more complex than this, since not all (P 2 P)Pt +2 complexes generated the ...
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New platinum(II) complexes with benzothiazole ligands
... in an orthorhombic unit cell with eight formula units. It is a square-planar complex with Pt—N and average Pt—Br bond lengths of 2.035 (5) and 2.433 (6) A ˚ , respectively, which are within the expected range for ...
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Testosterone as a delivery vector for platinum(II) metallodrugs
... The LD A, absorbance spectra B, change in LD versus DNA: complex ratio C and 204 expansion of the LD spectrum D of TC-ET-4-IQ with ct-DNA.. The LD A, absorbance spectrum B and change in [r] ...
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trans Dichlorobis(piperidine 1 carbonitrile)platinum(II)
... It has previously been observed that some push–pull nitrile- containing complexes, in particular dialkylcyanamide metal species, display unusual reactivity patterns unknown for conventional RCN compounds (Bokach et al., ...
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Design, Synthesis, and Reactivity of Bimetallic Complexes of Dimethylplatinum(II) Containing Ditopic Ligands
... conditions. Complex 2 proved to be incapable of coordinating an additional metal center in its potentially vacant coordination site independent of the geometry or size of the metal ...in complex 2 along ...
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A cytostatic ruthenium(II)-platinum(II) bis(terpyridyl) anticancer complex that blocks entry into S phase by up-regulating p27KIP1
... respective complex in each phase determined using high performance liquid chromatography (HPLC) coupled to a UV-vis ...respective complex was then ...
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Organometallic Compounds of the Platinum Metals16-22
... Although a platinum ethylene complex, Zeise’s salt, K[C,H,PtCl,], was the first platinum metal-indeed, the first transition metal-organometallic compound to be pre- [r] ...
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Studies on platinum (IV) ions sorption in loess and loamy soils
... of platinum in water environments as compared to distilled ...of platinum play a significant role in controlling the behaviour of platinum in surface environments, eg in the soil, and therefore the ...
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Bis(2 aminopyridine)(2,2′ bipyridine)platinum(II) tetracyanoplatinate(II) dihydrate
... The Pt Pt distances in (II) are reported as 3.9294 (6) and 5.0302 (7) AÊ (Sakai et al., 2003b), while those in (I) are Pt1 Pt2 = 5.2034 (6) AÊ and Pt1 Pt2(x ÿ 1, y, z) = 4.5599 (6) AÊ. The short Pt Pt distance ...
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trans Dichloridobis(3,4 dimethylpyridine)platinum(II)
... In the title compound, trans-[PtCl2C7H9N2], the PtII atom is located on an inversion center and is coordinated by two 3,4dimethylpyridine ligands and two chloride ligands, resulting in a[r] ...
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