Pneumococcal colonization
Inflammation Promotes Pneumococcal Colonization of the Respiratory Tract
... of pneumococcal colonization in children ...increase colonization density in the airway ...promote pneumococcal growth as a sole carbon source ...of pneumococcal exoglycosidases to ...
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Pneumococcal colonization in older adults
... of pneumococcal colonization was found in subjects who were ≥75 years ...Indeed, pneumococcal colonization was lower in subjects who were treated with a recent course of ...
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A Combination of Recombinant Mycobacterium bovis BCG Strains Expressing Pneumococcal Proteins Induces Cellular and Humoral Immune Responses and Protects against Pneumococcal Colonization and Sepsis
... ABSTRACT Pneumococcal diseases remain a substantial cause of mortality in young children in developing ...against colonization (likely medi- ated by interleukin-17A [IL-17A]) and invasive disease (likely ...
11
Immunization, Antibiotic Use, and Pneumococcal Colonization Over a 15-Year Period
... observe colonization with serotypes 1 or ...multiple pneumococcal serotypes with our approach to processing of nasopharyngeal ...affects pneumococcal colonization or clonal ...
11
Imputing direct and indirect vaccine effectiveness of childhood pneumococcal conjugate vaccine against invasive disease by surveying temporal changes in nasopharyngeal pneumococcal colonization
... A series of pneumococcal colonization studies were undertaken in mother-child pairs in Soweto (Gauteng, South Africa), with a population of 1.8 million of whom 160,000 are under five years of age (18). We ...
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Minimally Invasive Nasal Sampling in Children Offers Accurate Pneumococcal Colonization Detection
... assess pneumococcal colonization, NPS samples were placed in 1mL skim milk, tryptone, glucose, and glycerine (STGG) medium, 100µL of which was cultured on Columbia blood agar supplemented with 5% horse ...
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Pneumococcal Colonization Rates in Patients Admitted to a United Kingdom Hospital with Lower Respiratory Tract Infection: a Prospective Case Control Study
... and pneumococcal coloniza- tion has been previously noted in children, in whom those with radiologically confirmed pneumonia were more frequently colo- nized with pneumococci than those without (3) and had higher- ...
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Molecular Epidemiology of Pneumococcal Colonization in Response to Pneumococcal Conjugate Vaccination in Children with Recurrent Acute Otitis Media
... 7-valent pneumococcal conjugate vaccine was conducted in The Netherlands among 383 children, aged 1 to 7 years, with a history of recurrent acute otitis ...the pneumococcal colonization rate was ...
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Cellular effectors mediating Th17 dependent clearance of pneumococcal colonization in mice
... Microbial colonization of mucosal surfaces may be an initial event in the progression to disease, and it is often a transient process. For the extracellular pathogen Streptococcus pneumoniae studied in a mouse ...
12
Use of Multiplex Quantitative PCR To Evaluate the Impact of Pneumococcal Conjugate Vaccine on Nasopharyngeal Pneumococcal Colonization in African Children
... higher colonization density of nonvaccine serotype 5 and serogroup 23A/B was identified in PCV7-vaccinated children compared to PCV-unvaccinated children in the absence of a difference in overall ...
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Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization
... pneumococcal challenge associated with a resistance to carriage acquisition. MAIT cells were recently reported to be able to rec- ognize Spn through MHC class I–related protein 1–dependent (MR-1–dependent) and ...
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Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization
... Figure 4. Pneumococcal carriage leads to increased systemic plasmablasts. A) Levels of 6B polysaccharide-specific, 15B polysaccharide-specific, Pneumolysin derivative b (Pneumolysin)- specific or all plasmablast ...
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Impact of Experimental Human Pneumococcal Carriage on Nasopharyngeal Bacterial Densities in Healthy Adults
... Successful colonization with Sp was associated with an absence of Sa in samples 14 days ...that colonization with Sp always decreases prevalence of Sa at 14 days post-colonization, a time-delayed ...
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Pneumococcal Metabolic Adaptation and Colonization Are Regulated by the Two-Component Regulatory System 08
... as colonization factors (CF) accounted for 13 of the 159 genes displaying expression changes in the microarray ...in pneumococcal colonization and highlight the role of TCS08 for pneumococcal ...
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High Streptococcus pneumoniae colonization prevalence among HIV infected Kenyan parents in the year before pneumococcal conjugate vaccine introduction
... % pneumococcal colonization rate that we observed among HIV-infected adults is similar to a previous study conducted in Kenya among HIV clinic attendees ...overall colonization rate of ...African ...
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Immunization with Pneumococcal Surface Protein K of Nonencapsulated Streptococcus pneumoniae Provides Protection in a Mouse Model of Colonization
... in colonization and incidence of pneumococcal ...with pneumococcal proteins has been assessed for its ability to protect against pneumococcal disease, but several of these proteins are not ...
8
Pneumococcal carriage and antibiotic susceptibility patterns from two cross sectional colonization surveys among children aged <5 years prior to the introduction of 10 valent pneumococcal conjugate vaccine — Kenya, 2009–2010
... nasopharyngeal colonization, a necessary precursor to invasive disease. Pneumococcal conjugate vaccines can prevent colonization with vaccine serotype ...10-valent pneumococcal conjugate ...
12
Regulation of naturally acquired mucosal immunity to Streptococcus pneumoniae in healthy Malawian adults and children.
... low colonization we and others have shown that mucosal responses to pneumococcal proteins but not influenza antigens are regulated by CD25 hi cells in the majority of UK adults [7,10] and in children ...
6
Recent approaches in whole cell pneumococcal vaccine development: a review study
... on pneumococcal colonization ...of pneumococcal colonization in the nasopharynx of mice vaccinated with WCV and the levels of IL-17A in the blood; with non-detect- able numbers of pneumococci ...
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Role of pneumococcal vaccination in prevention of pneumococcal disease among adults in Singapore
... December 2010, one of the largest public hospitals piloted an innovative pre-discharge vaccination program for the first time in Singapore. This hospital-wide initiative integrates influenza and pneumococcal ...
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