Poly lactide co glycolide
Glycosaminoglycan-functionalized poly-lactide-co-glycolide nanoparticles: synthesis, characterization, cytocompatibility, and cellular uptake
... here poly- lactide-co-glycolide (PLGA) NPs in the range of 100–150 nm bearing various proteoglycans were synthesized by a single-step nanoprecipitation and ...
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Effect of Nigella Sativa Encapsulated in Poly (Lactide-Co-Glycolide) Nanoparticles on Plasma Malondialdehyde and Ischemia-Modified Albumin in A Diabetes Rat Model
... Introduction: An imbalance between pro-oxidant and endogenous antioxidant levels in diabetes mellitus (DM) leads to elevated levels of oxidative stress which triggers accumulation of lipid peroxidation products ...
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Evaluation of poly(lactide-co-glycolide)/hydroxyapatite nanofibres for reconstruction of critical-sized segmental bone defects in a canine model
... ABSTRACT: The treatment of segmental bone defects is a challenging problem for both human and veterinary medicine. Various biomaterials have successfully been used to treat these defects. Numerous recent in vitro studies ...
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Nanoparticles of Poly(Lactide Co Glycolide) d a Tocopheryl Polyethylene Glycol 1000 Succinate Random Copolymer for Cancer Treatment
... biodegradable poly(lactide-co-glycolide)-d-a-tocopheryl polyethylene gly- col 1000 succinate (PLGA-TPGS) random copolymer was synthesized from lactide, glycolide and ...
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Biological augmentation of rotator cuff repair using bFGF-loaded electrospun poly(lactide-co-glycolide) fibrous membranes
... Abstract: Clinically, rotator cuff tear (RCT) is among the most common shoulder pathologies. Despite significant advances in surgical techniques, the re-tear rate after rotator cuff (RC) repair remains high. Insufficient ...
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Development and characterization of Poly (lactide-co-glycolide) microspheres loaded with Flutamide, an anticancer drug for controlled drug delivery
... Poly (Lactide-co-glycolide) (PLGA) microspheres were prepared through Oil in Water (O/W) emulsion-solvent evaporation method using dichloromethane as solvent. Flutamide (FLT), an anti Cancer ...
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FORMULATION, CHARACTERIZATION AND DETERMINATION OF ANTI ALZHEIMERIC ACTIVITY OF TACRINE LOADED POLY (LACTIDE CO GLYCOLIDE) NANOPARTICLES
... loaded poly (lactide-co-glycolide) (PLGA) nanoparticles used for the treatment of alzheimer’s disease and were prepared by modified nano precipitation ...
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pH-sensitive poly(lactide-co-glycolide) nanoparticle composite microcapsules for oral delivery of insulin
... Abstract: This study proposes a new concept of pH-sensitive poly(lactide-co-glycolide) (PLGA) nanoparticle composite microcapsules for oral delivery of insulin. Firstly, insulin–sodium oleate ...
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Novel docetaxel loaded nanoparticles based on poly(lactide co caprolactone) and poly(lactide co glycolide co caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies
... block-copolymers, poly(lactide-co-caprolactone) (PLA-PCL) and poly (lactide-co-caprolactone-co-glycolide) (PLGA-PCL), were explored for the formulation of ...
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Electric Conductivity of Electrolytic Copper Powder Filled Poly(Lactide-co-Glycolide) Composites
... having poly(lactide-co-glycolide) (PLGA) matrix filled with electrolytically produced copper powder whose particles have a highly developed branched ...
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Induction of long lasting protective immunity against Toxoplasma gondii in BALB/c mice by recombinant surface antigen 1 protein encapsulated in poly (lactide co glycolide) microparticles
... as poly (lactide- co-glycolide) (PLG), have been used as safe, potent adjuvants or delivery systems to encapsulate antigens for preparing controlled-release microparticle vaccines ...
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Poly(lactide-co-glycolide)/Hydroxyapatite Porous Scaffold with Microchannels for Bone Regeneration
... Dunn et al. ever introduced an in situ solidification system composed of a poly(lactide-co- glycolide) (PLGA) implant in the 1990s [7]. This implant was dissolved in water miscible solvents, ...
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Poly (lactide -co- glycolide) Fiber: An Overview
... of lactide and glycolide acids in the polymer chain, molecular weight of the polymer, the degree of crystallinity, the Tg of the polymer and nature of the incubating media [24, ...of glycolide units, ...
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Nanofibrous poly(lactide-co-glycolide) membranes loaded with diamond nanoparticles as promising substrates for bone tissue engineering
... overnight with Dulbecco’s Modified Eagle Minimum Essential Medium (Sigma). The samples were then seeded with human osteoblast-like MG-63 cells (European Collection of Cell Cultures, Salisbury, UK). Each well contained ...
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Poly(lactide- co -glycolide)/Hydroxyapatite Scaffold
... of collagen coating and DGEA improved scaffold properties for bone regeneration, thereby 27.. providing a new potential strategy for scaffold design.[r] ...
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Preparation, characterization, and safety evaluation of poly(lactide-<em>co</em>-glycolide) nanoparticles for protein delivery into macrophages
... Biodegradable PLGA 50:50 polymer of 7,000–17,000 daltons average molecular weight (MW), BSA, and fluorescein iso- thiocyanate (FITC)-labeled BSA were all purchased from Sigma-Aldrich Co. (St Louis, MO, USA). ...
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Humoral Immune Response Induced by PLGA Micro Particle Coupled Newcastle Disease Virus Vaccine in Chickens
... by Poly Lactide-co-Glycolide Acid (PLGA) microspheres coupled inactivated Newcastle Disease Virus (NDV) vaccine in comparison to an ‘in-house’ prepared inactivated and a live commercial ...
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Benefits of biphasic calcium phosphate hybrid scaffold-driven osteogenic differentiation of mesenchymal stem cells through upregulated leptin receptor expression
... A composite system was developed using poly(lactide-co- glycolide) (PLGA) copolymer, coralline HA, BCP ceramics, and collagen as a carrier matrix for MSCs. PLGA (300 mg; Boehringer Ingelheim, ...
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Robust aptamer–polydopamine-functionalized M-PLGA–TPGS nanoparticles for targeted delivery of docetaxel and enhanced cervical cancer therapy
... Here, we reported a robust aptamer–polydopamine-functionalized mannitol-functionalized poly(lactide-co-glycolide) (M-PLGA)– d - α -tocopheryl polyethylene glycol 1000 succinate (TPGS) [r] ...
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“Pharmacokinetic Study of Dry Powder Inhaler Formulations of Antiasthmatic Drugs” by Dhara P. Jain, Parag Vijay Jain, M. R. Bhalekar, India.
... of poly lactic acid (PLA) and poly (lactide-co-glycolide) (PLGA) can be considered as a well established drug delivery system, having high potential to serve as carriers for drugs as ...
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