polycythemia vera
Neutropenia caused by hairy cell leukemia in a patient with myelofibrosis secondary to polycythemia vera: a case report
... referred to the local department of hematology because of leukopenia and thrombocytopenia. A bone marrow biopsy showed mildly increased total cellularity (55%), increased numbers of megakaryocytes, no significant in- ...
6
“Study of JAK2 V617F mutation, serum B12 level and interleukin – 23 level in polycythemia vera
... erythrocytosis (polycythemia) and or granulocytosis and thrombocytosis in the peripheral blood. But erythrocytosis is responsible for most of the clinical symptoms (Nayak et al., 2012). It has been found that ...
8
The Frequency of Thromboembolism and Factors Associated with Thromboembolism in Patients Suffering from Polycythemia Vera
... Polycythemia vera (PV) is an acquired stem cell disease included among BCR-ABL-negative myeloproliferative neoplasms. It is a chronic and clonal in nature, and characterized by uncontrolled proliferation of ...
6
Erythrocytosis caused by giant chromophobe renal cell carcinoma: a case report indicating a 9-year misdiagnosis of polycythemia vera
... Case presentation: We report a case of a young man suffering from a giant (22-cm) mass on his left kidney. Because of a history of polycythemia vera, the patient had been treated for the condition for 9 ...
6
<p>Ruxolitinib In The Treatment Of Polycythemia Vera: An Update On Health-Related Quality Of Life And Patient-Reported Outcomes</p>
... Polycythemia vera (PV) is a rare myeloproliferative neoplasm (MPN) characterized by increased red blood cell mass, bone marrow panmyelosis, and Janus kinase 2 (JAK2) ...
10
The role of certain gene polymorphisms involved in the apoptotic pathways in polycythemia vera and essential thrombocytosis
... Clonal myeloproliferative neoplasms (MPN) are clas- sified into 2 major groups. While classical MPNs are represented by chronic Ph-positive myeloid leukemia (CML), carrying the Philadelphia (Ph) translocation and the ...
5
<p>Polycythemia Vera-Associated Complications: Pathogenesis, Clinical Manifestations, And Effects On Outcomes</p>
... Abstract: Polycythemia vera is a Philadelphia-negative chronic myeloproliferative neo- plasm, characterized by erythrocytosis, which is unique, compared to essential thrombocy- tosis and primary myelo fi ...
13
A Rare Cause of Gastrointestinal Bleeding in a 65-Year-Old Man with History of Polycythemia Vera
... Polycythemia vera (PV) is classified as a myeloproliferative disorder (MPD). Such patients are prone to both thrombotic and hemorrhagic events. Although gastrointestinal (GI) bleeding is not a prominent ...
5
Are patients with high-risk polycythemia vera receiving cytoreductive medications? A retrospective analysis of real-world data
... AML: acute myeloid leukemia; CDHP: consumer-driven health plan; ELN: Euro- pean LeukemiaNet; EPO: exclusive provider organization; HDHP: high-deduct- ible health plan; HMO: health maintenance organization; IV: ...
6
Case Report on Feline Polycythemia Vera
... Polycythemia vera has been reported as a known condition in cats as early as ...setting. Polycythemia vera is relatively uncommon in dogs and cats, but should still be considered in cases of ...
7
In vitro studies of human pluripotential hematopoietic progenitors in polycythemia vera Direct evidence of stem cell involvement
... Previous in vitro studies on committed hematopoietic progenitors have suggested that polycythemia vera (PV) is a clonal disorder arising in a pluripotential hematopoietic stem cell. In this study, recently ...
8
Unregulated proliferation of primitive neoplastic progenitor cells in long term polycythemia vera marrow cultures
... Marrow cells from seven untreated patients with polycythemia vera (PV) were used to initiate standard single inoculum long-term marrow cultures. The numbers, erythropoietin independence, and cycling ...
6
Granulocyte Alkaline Phosphatase STUDIES OF PURIFIED ENZYMES FROM NORMAL SUBJECTS AND PATIENTS WITH POLYCYTHEMIA VERA
... with polycythemia vera, the enzyme was purified from granule fractions of sucrose homogenates made from dextran-sedimented leukocytes of normal subjects and patients with polycythemia ...
9
Histomorphological responses after therapy with pegylated interferon α-2a in patients with essential thrombocythemia (ET) and polycythemia vera (PV)
... and polycythemia vera (PV) are BCR-ABL–negative myeloproliferative neoplasms (MPN) characterized by an overproduction of mature blood elements, tendencies toward thrombosis and hem- orrhage, extramedullary ...
13
Erythroid colony formation by polycythemia vera bone marrow in vitro Dependence on erythropoietin
... In the plasma clot culture system both normal and polycythemia vera (PV) bone marrow cells respond to erythropoietin (Ep), giving rise to large numbers of colonies of erythroid cells. In PV, but not in ...
9
Ruxolitinib: a targeted treatment option for patients with polycythemia vera
... Abstract: Polycythemia vera (PV) is a chronic myeloproliferative neoplasm characterized by erythrocytosis and the presence of Janus kinase (JAK) 2V617F or similar ...
13
Serum Levels of Testosterone in Patients with Polycythemia Vera
... However, we previously reported that serum levels of total cholesterol, low-density lipoprotein cholesterol, and apolipoprotein B were significantly lower in patients with polycythemia vera (PV) than in ...
6
Changes in peripheral blood lymphocytes in polycythemia vera and essential thrombocythemia patients treated with pegylated-interferon alpha and correlation with JAK2 V617F allelic burden
... PV: polycythemia vera; ET: essential thrombocytemia; MPN: myeloproliferative neoplasms; INFα: interferon alpha; PegINFα: pegylated‑interferon alpha; HU: hydroxyurea; PBL: peripheral bl[r] ...
9
Torque Teno Virus 10 Isolated by Genome Amplification Techniques from a Patient with Concomitant Chronic Lymphocytic Leukemia and Polycythemia Vera
... An infectious etiology has been proposed for many human cancers, but rarely have specific agents been identified. One diffi- culty has been the need to propagate cancer cells in vitro to produce the infectious agent in ...
11
Driver mutations (JAK2V617F, MPLW515L/K or CALR), pentraxin-3 and C-reactive protein in essential thrombocythemia and polycythemia vera
... Methods: We evaluated 305 with essential thrombocythemia (ET) and 172 polycythemia vera (PV) patients diagnosed according to the 2016 WHO criteria and with full molecular characterization for driver ...
8