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Polymorphonuclear Leukocytes

Oxidative cross linking of immune complexes by human polymorphonuclear leukocytes

Oxidative cross linking of immune complexes by human polymorphonuclear leukocytes

... human polymorphonuclear leukocytes for 1 h at 37 degrees C resulted in covalent cross-linking of ...lysates, polymorphonuclear granules, and purified human myeloperoxidase in the presence of a steady ...

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Killing of gram negative bacteria by polymorphonuclear leukocytes: role of an O2 independent bactericidal system

Killing of gram negative bacteria by polymorphonuclear leukocytes: role of an O2 independent bactericidal system

... human polymorphonuclear leukocytes is the principal O2- independent bactericidal agent of these cells toward several strains of Escherichia coli and Salmonella typhimurium ...by polymorphonuclear ...

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Activation of the respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattractants and other soluble stimuli  Evidence that the same oxidase is activated by different transductional mechanisms

Activation of the respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattractants and other soluble stimuli Evidence that the same oxidase is activated by different transductional mechanisms

... Activation of the Respiratory Burst Enzyme in Human Polymorphonuclear Leukocytes by Chemoattractants and Other Soluble Stimuli EVIDENCE THAT THE SAME OXIDASE IS ACTIVATED BY DIFFERENT TR[r] ...

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Membrane bound lactoferrin alters the surface properties of polymorphonuclear leukocytes

Membrane bound lactoferrin alters the surface properties of polymorphonuclear leukocytes

... Polymorphonuclear leukocytes (PMN) aggregate and avidly attach to endothelium in response to chemotactic agents. This response may be related in part to the release of the specific granule constituent ...

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Physiologic-Chemoattractant-Induced Migration of Polymorphonuclear Leukocytes in Milk

Physiologic-Chemoattractant-Induced Migration of Polymorphonuclear Leukocytes in Milk

... The somatic cell count (SCC; leukocytes and epithelial cells) in milk is used as an indicator of udder health status. A SCC above the regulatory standard is generally considered as an indication of mastitis. ...

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Chemotaxis of polymorphonuclear leukocytes from patients with rheumatoid arthritis

Chemotaxis of polymorphonuclear leukocytes from patients with rheumatoid arthritis

... Using a new in vitro method of measuring the chemotaxis of polymorphonuclear leukocytes from peripheral blood, a chemotactic index has been calculated. The mean chemotactic index of 320 in 24 patients with ...

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Lipids of alveolar macrophages, polymorphonuclear leukocytes, and their phagocytic vesicles

Lipids of alveolar macrophages, polymorphonuclear leukocytes, and their phagocytic vesicles

... phospholipids of the phagocytic vesicle fraction from macrophages contained relatively more sphingomyelin, lyso-(bis)phosphatidic acid, and phosphatidylserine and less lecithin, phosphatidylethanolamine, and ...

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Chemiluminescence of Human and Canine Polymorphonuclear Leukocytes in the Absence of Phagocytosis

Chemiluminescence of Human and Canine Polymorphonuclear Leukocytes in the Absence of Phagocytosis

... Polymorphonuclear leukocytes (PMNs) have increased oxidative metabolism during phagocytosis and emit light (chemiluminescence, CL) as a result of metabolic ...

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Rapid changes in light scattering from human polymorphonuclear leukocytes exposed to chemoattractants  Discrete responses correlated with chemotactic and secretory functions

Rapid changes in light scattering from human polymorphonuclear leukocytes exposed to chemoattractants Discrete responses correlated with chemotactic and secretory functions

... chemotaxis but to inhibit secretion and superoxide anion production, abolished the slow perpendicular light-scattering response but left the fast response intact. Stimulants of secretion induced only slow and prolonged ...

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In Vitro Bactericidal Capacity of Human Polymorphonuclear Leukocytes: Diminished Activity in Chronic Granulomatous Disease of Childhood

In Vitro Bactericidal Capacity of Human Polymorphonuclear Leukocytes: Diminished Activity in Chronic Granulomatous Disease of Childhood

... polymorphonuclear leukocytes (PMN) from five children with the clinical syndrome of granulomatous disease of childhood. The PMN from these children demonstrated nearly normal phagocytic capacity, and the ...

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BACTERICIDAL FUNCTION OF HUMAN POLYMORPHONUCLEAR LEUKOCYTES

BACTERICIDAL FUNCTION OF HUMAN POLYMORPHONUCLEAR LEUKOCYTES

... : In vitro bactericidal capacity of human polymorphonuclear leukocytes: Di- minished activity in chronic granulomatous. disease of childhood[r] ...

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Oxidation of Methionine by Human Polymorphonuclear Leukocytes

Oxidation of Methionine by Human Polymorphonuclear Leukocytes

... phagocytosing human polymorphonuclear leukocytes (PMN), but not resting PMN, oxidized both intracellular and extracellular methionine to methionine sulfoxide. N-ethylmaleimide, which inhibits phagocytosis ...

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Leukotriene biosynthesis by polymorphonuclear leukocytes from two patients with chronic granulomatous disease

Leukotriene biosynthesis by polymorphonuclear leukocytes from two patients with chronic granulomatous disease

... Polymorphonuclear leukocytes PMNL isolated from two patients with chronic granulomatous disease CGD were tested for their ability to metabolize arachidonic acid to lipoxygenase products [r] ...

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In vitro suppression of serum elastase inhibitory capacity by reactive oxygen species generated by phagocytosing polymorphonuclear leukocytes

In vitro suppression of serum elastase inhibitory capacity by reactive oxygen species generated by phagocytosing polymorphonuclear leukocytes

... Human polymorphonuclear leukocytes (PMN) phagocytosing opsonized antigen-antibody complexes, produce dialyzable species of activated oxygen which are capable of partially suppressing the elastase-inhibiting ...

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Separation of sublethal and lethal effects of polymorphonuclear leukocytes on Escherichia coli

Separation of sublethal and lethal effects of polymorphonuclear leukocytes on Escherichia coli

... coli ML-35 and 0111:B4 promptly lost their ability to form colonies in nutrient agar both in the absence and presence of BSA, with a coincident inhibition of bacterial protein synthesis [r] ...

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The Anticoagulant Activity of Lysosomal Cationic Proteins from Polymorphonuclear Leukocytes

The Anticoagulant Activity of Lysosomal Cationic Proteins from Polymorphonuclear Leukocytes

... The anticoagulant activity is detectable in the whole blood clotting time, the recalcification time of platelet-rich plasma, the prothrombin time, the partial thromboplastin time, and th[r] ...

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Further characterization of NADPH oxidase activity of human polymorphonuclear leukocytes

Further characterization of NADPH oxidase activity of human polymorphonuclear leukocytes

... Activity was present in granules iso- Mn2", it seemed necessary to examine the effect of superlated from cells challenged with opsonized zymosan, oxide on the Mn+-catalyzed oxidation of [r] ...

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The role of lysosomal elastase in the digestion of Escherichia coli proteins by human polymorphonuclear leukocytes: experiments with living leukocytes

The role of lysosomal elastase in the digestion of Escherichia coli proteins by human polymorphonuclear leukocytes: experiments with living leukocytes

... homogenized leukocytes, suggesting that lysosomal degranulation had not been suppressed by the ...the leukocytes had phagocytized chloromethyl ketone-treated ...

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Superoxide Dismutases in Polymorphonuclear Leukocytes

Superoxide Dismutases in Polymorphonuclear Leukocytes

... of leukocytes released large amounts of superoxide into the medium when the cells were phagocytizing, suggesting that, if the cell population is homogeneous, superoxide production probably takes place on the outer ...

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Isolation and Properties of Phagocytic Vesicles from Polymorphonuclear Leukocytes

Isolation and Properties of Phagocytic Vesicles from Polymorphonuclear Leukocytes

... Uptake of particles and the transfer of total protein and phospholipid into phagocytic vesicles occurred simultaneously Accumulation of acid and alkaline phosphatase in the vesicles cont[r] ...

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