Pore-forming
Cholesterol-Dependent Cytolysins and Perforin: Similar Pore-Forming Mechanisms in Pathogenic Attack and Human Immune Defense
... trans-membrane pore was clear from the ...PFN pore-forming activity in vitro but much attention was also concentrated on cellular function of this cytolytic protein of the immune system (in vivo ...
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A Natural Chimeric Pseudomonas Bacteriocin with Novel Pore Forming Activity Parasitizes the Ferrichrome Transporter
... The pmnH gene (1,389 bp) occurs in isolates from several Pseudomonas species, originating from diverse sources such as rhizosphere, water, and cystic fibrosis lung: Pseudomonas fluorescens (AU14440, LBUM223, KENGFT3, and ...
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Degradation Products of the Extracellular Pathogen Streptococcus pneumoniae Access the Cytosol via Its Pore Forming Toxin
... the pore-forming toxin pneumolysin and allows the transit of bacterial components across the phagosome membrane to the cytosol, where they can be detected by intracellular host ...of pore formation ...
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Analysis on Pore Forming Pouring Pile Construction Technology of House Building Project
... the pore-forming pouring pile is more simple and convenient, with a wider range of ...the pore-forming pouring pile technology, analyzes the pore-forming construction technology ...
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Structural and Functional Analysis of the Pore Forming Toxin NetB from Clostridium perfringens
... secreted pore-forming toxin NetB is a key virulence fac- tor in the pathogenesis of avian necrotic enteritis and is similar to alpha-hemolysin, a -barrel pore-forming toxin from Staphy- ...
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EFFECT OF VARIOUS OSMOGENS ON DRUG RELEASE PROFILES OF SELF PORE FORMING OSMOTIC TABLETS OF AZATHIOPRINE
... self pore forming osmotic pump consists of the core containing the active material and a semi permeable membrane that coats the core, having a self pore forming material to produce orifices in ...
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Molecular architecture and functional analysis of NetB, a pore forming toxin from Clostridium perfringens
... after size-exclusion chromatography (see “Experimental Proce- dures”). Detergents that efficiently solubilized NetB were then used for crystallization trials. Only NetB solubilized in C10E6 yielded crystals that ...
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The membrane attack complex, perforin and cholesterol dependent cytolysin superfamily of pore forming proteins
... Pore-forming proteins (PFPs) are initially soluble proteins that can bind to membranes, oligomerise and convert to membrane-inserted pores of 1 – 50 nm in diameter that are formed of six to 50 or more ...
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Ostreolysin A/Pleurotolysin B and Equinatoxins: Structure, Function and Pathophysiological Effects of These Pore-Forming Proteins
... a pore-forming cytolysin which belongs to the larger group of highly homologous proteins called aegerolysins (Pfam PF06355, InterPro IPR009413), currently comprising more than 350 entries in the NCBI ...the ...
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Ostreolysin A/Pleurotolysin B and Equinatoxins: Structure, Function and Pathophysiological Effects of These Pore-Forming Proteins
... 57. Kahn, S.A.; Biasoli, D.; Garcia, C.; Geraldo, L.H.; Pontes, B.; Sobrinho, M.; Frauches, A.C.; Romao, L.; Soletti, R.C.; Assuncao Fdos, S., et al. Equinatoxin II potentiates temozolomide- and etoposide-induced ...
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Pseudomonas aeruginosa Pore Forming Exolysin and Type IV Pili Cooperate To Induce Host Cell Lysis
... a pore-forming activity which pre- cedes cell membrane disruption of nucleated ...a pore-forming toxin of the TPS family and surface appendages in host cell ...
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An Intermolecular π Stacking Interaction Drives Conformational Changes Necessary to β Barrel Formation in a Pore Forming Toxin
... The studies herein show that the intermolecular -stacking of Y181A with F318A is necessary to disrupt interactions between ␣ HB2 and the core  -sheet mediated by the Met-Met-Phe triad of residues. The disruption of ...
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Human Specific Bacterial Pore Forming Toxins Induce Programmed Necrosis in Erythrocytes
... of pore-forming toxins (PFTs) has an unusually nar- row host range due to a requirement for binding to human CD59 (hCD59), a glycosylphosphatidylinositol (GPI)-linked comple- ment regulatory ...
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Understanding gene expression with a pore forming toxin
... to pore formation rather than to “sublytic” concentrations, ...of pore forming toxins to host cells may be those relevant for understanding the physiopathology of these virulence factors in ...
200
Disarming Pore-Forming Toxins with Biomimetic Nanosponges in Intraocular Infections
... neutralize pore-forming toxins from the most frequent Gram-positive bacterial causes of intraocular infections (Staphylococcus aureus, En- terococcus faecalis, Streptococcus pneumoniae, and Bacillus ...
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Application of Organic Additives as Pore Forming Agents for Geopolymer Composites
... using pore forming agents, however research in this field remains ...organic pore forming agents (POF) for fly-ash geopolymers to create pores of various size ranges in the ...
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pH-triggered endosomal escape of pore-forming Listeriolysin O toxin-coated gold nanoparticles
... the pore-forming Listeria monocytogenes Listeriolysin O (LLO) toxin as a “proof of concept” to promote the lysosomal escape of Au-NPs inside mouse embryonic fibroblasts (MEFs) and reduce or even prevent ...
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Identification and structural analysis of the tripartite α pore forming toxin of Aeromonas hydrophila
... AhC subunits of the soluble tetramer adopt a pore type con- formation with the hydrophobic heads buried within the tail domains of symmetry related subunits. Thus some disassembly of the AhlC tetramer must occur ...
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Synthesis of a Highly Porous Nitrogen-Doped Carbon Material from a Melamine/Formaldehyde Resin with Potassium Citrate
... In this work, we present a new synthesis approach to fabricate N-doped porous carbons with large surface areas by incorporating the pore forming agent potassium citrate into the melamine/formaldehyde resin. ...
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Impact of Dye Sensitized Solar Cell Anode Preparation on Performance
... Conclusions This paper focuses on the annealing temperature, pore-forming agent PEG molecular weight of the two parameters on the dye-sensitized TiO2 thin film photovoltaic solar cell pe[r] ...
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