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Post-transcription

Icaritin inhibits the expression of alpha-fetoprotein in hepatitis B virus-infected hepatoma cell lines through post-transcriptional regulation

Icaritin inhibits the expression of alpha-fetoprotein in hepatitis B virus-infected hepatoma cell lines through post-transcriptional regulation

... on post-transcriptional regulation of AFP gene, as well as the effects of HBV infection and icaritin in hepatoma ...the post-transcriptional regulation of ...

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MicroRNAs and Toll-like Receptor/Interleukin-1 Receptor Signaling

MicroRNAs and Toll-like Receptor/Interleukin-1 Receptor Signaling

... Prior to recent breakthroughs, it was believed that the majority of DNAs were transcribed to mRNAs and then translated into proteins. The remaining RNAs not coding for protein were either ribosomal RNAs, transfer RNAs, ...

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Interplay between Cholesterol, SREBPs, MicroRNA-33 in Dyslipidemia

Interplay between Cholesterol, SREBPs, MicroRNA-33 in Dyslipidemia

... Recently, non-coding RNA termed microRNAs (miRNAs) has been identified in cholesterol and lipid metabolism as a crucial regulator of gene expression and acting primarily at the post-transcriptional level of ...

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MicroRNA 362 Inhibits Cell Proliferation and Invasion by Directly Targeting SIX1 in Colorectal Cancer

MicroRNA 362 Inhibits Cell Proliferation and Invasion by Directly Targeting SIX1 in Colorectal Cancer

... MicroRNAs miRNAs, non-coding short RNAs of 19–24 nucleotides in length, cleave mRNA or bind to target mRNA to cause mRNA degradation or translational repression at the post-transcription[r] ...

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The L-Type Cyclin CYL-1 and the Heat-Shock-Factor HSF-1 Are Required for Heat-Shock-Induced Protein Expression in Caenorhabditis elegans

The L-Type Cyclin CYL-1 and the Heat-Shock-Factor HSF-1 Are Required for Heat-Shock-Induced Protein Expression in Caenorhabditis elegans

... general transcription or a post-transcriptional aspect of gene ...heat-shock-inducible transcription and CYL-1 acts more generally in gene ...

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Pseudomonas aeruginosa induces pigment production and enhances virulence in a white phenotypic variant of Staphylococcus aureus

<em>Pseudomonas aeruginosa</em> induces pigment production and enhances virulence in a white phenotypic variant of <em>Staphylococcus aureus</em>

... Figure 4 Transcriptional analysis of selected genes from the Staphylococcus aureus white variant after co-culture with Pseudomonas aeruginosa. several genes involved in pigment production were analyzed by qRT-PcR after ...

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Putting an ‘End’ to HIV mRNAs: capping and polyadenylation as potential therapeutic targets

Putting an ‘End’ to HIV mRNAs: capping and polyadenylation as potential therapeutic targets

... of post-transcriptional con- trol of gene expression that many processes are networked and factors can appear to be ‘moonlighting’ to perform a variety of functions in the ...and transcription termination ...

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Long non-coding RNAs AC026904.1 and UCA1: a “one-two punch” for TGF-β-induced SNAI2 activation and epithelial-mesenchymal transition in breast cancer

Long non-coding RNAs AC026904.1 and UCA1: a “one-two punch” for TGF-β-induced SNAI2 activation and epithelial-mesenchymal transition in breast cancer

... LncRNAs are a large heterogeneous class of transcripts longer than 200 nucleotides with limited protein-coding potential[14]. Recent evidence has demonstrated that lncRNAs are pervasively transcribed throughout ...

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From Faulty Biochemical Assumptions to Poor Diagnostic Performance: Reflections on the Failure of DNA Microarrays to Become a Reliable Clinical Diagnostic Tool

From Faulty Biochemical Assumptions to Poor Diagnostic Performance: Reflections on the Failure of DNA Microarrays to Become a Reliable Clinical Diagnostic Tool

... each transcription is supported by a number of transcription factors expressed by many ...the transcription rates of genes and the mRNA abundances are the 'many-to-one', not the 'one-to-one'; ...

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Pka, Ras and RGS Protein Interactions Regulate Activity of AflR, a Zn(II)2Cys6 Transcription Factor in Aspergillus nidulans

Pka, Ras and RGS Protein Interactions Regulate Activity of AflR, a Zn(II)2Cys6 Transcription Factor in Aspergillus nidulans

... Zn(II)2Cys6 transcription factor, AflR. aflR is transcriptionally and post-transcriptionally regulated by a G-protein/ cAMP/protein kinase A (PkaA) signaling pathway involving FlbA, an RGS (regulator of ...

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Genomic Methods for Studying the Post-Translational Regulation of Transcription Factors

Genomic Methods for Studying the Post-Translational Regulation of Transcription Factors

... The network inference methods discussed in Section 1.2 only consider regulatory interactions between TFs and target genes, and are therefore limited in terms of the biological phenomena they can explain. Although TF ...

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Effects of a temperature-sensitive mutation in the immediate-early gene of pseudorabies virus on class II and class III gene transcription.

Effects of a temperature-sensitive mutation in the immediate-early gene of pseudorabies virus on class II and class III gene transcription.

... First, the tsG mutation inhibits the formation of new transcription complexes on class II genes, but does not affect transcription from preestablished transcription complexes formed in t[r] ...

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Integration Site Preference of Xenotropic Murine Leukemia Virus-Related Virus, a New Human Retrovirus Associated with Prostate Cancer

Integration Site Preference of Xenotropic Murine Leukemia Virus-Related Virus, a New Human Retrovirus Associated with Prostate Cancer

... with transcription units and repetitive ...a transcription unit and repetitive elements by using the Na- tional Center for Biotechnology Information (NCBI) human Reference Sequence (RefSeq) gene database ...

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Interspecific  and acclimation induced variation in levels of heat shock proteins 70 (hsp70) and 90 (hsp90) and heat shock transcription factor 1 (HSF1) in congeneric marine snails (genus Tegula): implications for regulation of hsp gene expression

Interspecific and acclimation induced variation in levels of heat shock proteins 70 (hsp70) and 90 (hsp90) and heat shock transcription factor 1 (HSF1) in congeneric marine snails (genus Tegula): implications for regulation of hsp gene expression

... Endogenous levels of hsps and HSF1 were measured to elucidate the mechanisms underlying the inter- and intraspecific variation in hsp gene expression discovered in our earlier studies of hsp synthesis in congeners of ...

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Characterisations of odorant-binding proteins in the tsetse fly Glossina morsitans morsitans

Characterisations of odorant-binding proteins in the tsetse fly Glossina morsitans morsitans

... The transcription of these genes in the antennae was significantly lower in males than in females and there was a clear correlation between OBP gene transcription and feeding ...h post-blood meal ...

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Disruption of the transcription factors Thi2p and Nrm1p alleviates the post-glucose effect on xylose utilization in Saccharomyces cerevisiae

Disruption of the transcription factors Thi2p and Nrm1p alleviates the post-glucose effect on xylose utilization in Saccharomyces cerevisiae

... the transcription of hexose transporters [24]; the Snf1– Mig1 pathway largely functions in repressing the genes involved in non-fermentable carbon metabolism [25]; and the most important pathway, the cAMP–PKA ...

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Dual roles of the bZIP transcription factor PERIANTHIA in the control of floral architecture and homeotic gene expression

Dual roles of the bZIP transcription factor PERIANTHIA in the control of floral architecture and homeotic gene expression

... domain transcription factors of the SEPALLATA class (SEP1, SEP2, SEP3 and SEP4), which form tetrameric complexes with different combinations of homeotic ABC factors (Ditta et ...

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A reverse-engineering approach to dissect post-translational modulators of transcription factor's activity from transcriptional data

A reverse-engineering approach to dissect post-translational modulators of transcription factor's activity from transcriptional data

... Here, we developed and applied a new reverse- engineering strategy called Differential Multi-Information (DMI or ΔI method) to infer post-translational modula- tors of a TF of interest. Our working hypothesis is ...

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Bacterial Nucleoid Associated Protein Uncouples Transcription Levels from Transcription Timing

Bacterial Nucleoid Associated Protein Uncouples Transcription Levels from Transcription Timing

... a transcription factor that do not function in the context of such a temporal program would have no reason, a priori, to exhibit an elaborate temporal expression ...

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Expression of the transcription factor, TFII I, during post implantation mouse embryonic development

Expression of the transcription factor, TFII I, during post implantation mouse embryonic development

... General transcription factor (TFII-I) is a multi-functional transcription factor encoded by the Gtf2i gene, that has been demonstrated to regulate transcription of genes critical for ...in ...

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