Post-transcriptional control
Alternative cleavage and polyadenylation in spermatogenesis connects chromatin regulation with post-transcriptional control
... Here we show widespread shortening of 3’UTR by APA in spermatogenesis, with 3’UTRs being the shortest in spermatids. By combining our data with other data, in- cluding RNA-seq, RNAPII binding and H3K4me3 signals, we ...
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Post transcriptional control by bacteriophage T4: mRNA decay and inhibition of translation initiation
... in post-transcriptional control, including the genetic code, mRNA, and tRNA; the very foundations of molecular ...of post-transcriptional control are also ...
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Post transcriptional control of tumor cell autonomous metastatic potential by the CCR4 NOT deadenylase CNOT7
... result, control of transcriptional programs in the metastatic cascade has been the focus of many studies over the past ...3]. Post-transcriptional control of metastasis-associated genes ...
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Post-Transcriptional Control of Interferon Synthesis
... 9 found that if cycloheximide was present in rabbit kidney cell cultures for only 3 to 4 hr after poly I: poly C treatment and then removed, the amount I:poly C-stimulated interferon pro[r] ...
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Post transcriptional control of the epigenetic stem cell regulator PLZF by sirtuin and HDAC deacetylases
... (a). Transcriptional repression by PLZF is blocked by HDAC3 ...h post transfection and luciferase assays ...panel control of PLZF expression using immunoblotting detection with a FLAG antibody ...
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A role for post transcriptional control of endoplasmic reticulum dynamics and function in C elegans germline stem cell maintenance
... The FAR/STRIPAK complex is involved in various cellular processes, including vesicular trafficking/dynamics, cell migration, cell cycle control and signaling (Hwang and Pallas, 2014; Lant et al., 2015). ...
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Pervasive post transcriptional control of genes involved in amino acid metabolism by the Hfq dependent GcvB small RNA
... Salmonella RNA was isolated using the Promega SV total RNA purification kit. Microarrays used in this study were produced by insitu synthesis as 8x15k multipack format from Agilent Technologies (Agilent AMADID ...
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Multiple Transcriptional and Post-transcriptional Pathways Collaborate to Control Sense and Antisense RNAs of Tf2 Retroelements in Fission Yeast
... Tf2 transcriptional si- lencing (Cam et ...the post- transcriptional control of Tf2 mRNA accumulation by Pab2/ Rrp6-mediated RNA elimination (this study and Yamanaka et ...of ...
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The synthesis of polynucleotides for interferon induction
... inhibitors of interferon are present, one which operates at a genetic level the repressor and controls the synthesis of interferon m-RNA and the other a post-transcriptional control prot[r] ...
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<em>Pseudomonas aeruginosa</em> induces pigment production and enhances virulence in a white phenotypic variant of <em>Staphylococcus aureus</em>
... 4 Transcriptional analysis of selected genes from the Staphylococcus aureus white variant after co-culture with Pseudomonas ...synthesis. Transcriptional factors sigB and sara control the expression ...
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The Mitotic Genome: Accessibility and Transcriptional Control
... the post-mitotic transcriptional spike? It is unclear whether this phenomenon has been programmed to serve a natural ...the transcriptional control of genes that are under regulatory ...
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Myc Enforces Overexpression of EZH2 in Early Prostatic Neoplasia via Transcriptional and Post-transcriptional Mechanisms
... of transcriptional activation by Myc in prostate cancer, we carried out chromatin immunoprecipitation (ChIP), and enriched Myc binding approximately 1kb and 2kb upstream of the transcription start site of EZH2, ...
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Transcriptional Control of D-beta-2
... A growing body of evidence has established a role for germline promoters in regulating the recombinational accessibility of discrete domains within individual antigen receptor loci. Promoters are proposed to provide a ...
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Transcriptional control in the prereplicative phase of T4 development
... T4 also encodes two other ADP-ribosylating enzymes, ModA and ModB, as early products. Like Alt, ModA modifies Arg265 of RNAP a [[53,48]; reviewed in [1,4]]. However, unlike Alt, ModA almost exclusively targets the RNAP a ...
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Magnesium Therapy Prevents Senescence with the Reversal of Diabetes and Alzheimer’s Disease
... Sirt1 is a Nicotinamide Adenine Dinucleotide (NAD) + dependent class III histone deacetylase protein that targets nuclear receptors to regulate several cell functions by deacetylating both histone and non-histone targets ...
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The remote transcriptional control of Hox genes
... Targeted rearrangements at Hox clusters revealed the impor- tance of the cluster organization for the coordinated expression of Hox genes. For instance, relocalization of Hoxd9- and Hoxd11-lacZ transgenes into a 5’ ...
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Post transcriptional regulation of myotube elongation and myogenesis by Hoi Polloi
... (Thisse and Thisse, 2001). We asked whether nhp2l1b is essential for zebrafish muscle development using two independent MOs to knockdown endogenous nhp2l1b. One MO targets the nhp2l1b translational start site with 100% ...
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Post-transcriptional restriction of human adenovirus expression in monkey cells.
... Post-Transcriptional Restriction of Human Adenovirus Expression in Monkey Cells LARRY ERON, HEINER WESTPHAL,* AND GEORGE KHOURY Laboratory of Molecular Genetics, National Institute of Ch[r] ...
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Synaptic Signal Transduction and Transcriptional Control
... An ideal system would allow repeated measurements of the same sample after acute knockdown. For other purposes, gene silencing has been achieved in vivo within hours using oligodeoxynucleotides (Guzowski et al., 2000). ...
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Transcriptional and post-transcriptional regulation of retrotransposons IAP and MuERV-L affect pluripotency of mice ES cells
... endogenous transcriptional activity of REs in ES cell ...the transcriptional gene silencing by methylation, other post-transcriptional processes are involved in gene silencing of some ...some ...
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