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postsynaptic membrane

Cell culture-based analysis of postsynaptic membrane assembly in muscle cells

Cell culture-based analysis of postsynaptic membrane assembly in muscle cells

... Moreover, the secondary plating method provides a means to determine the signaling events connecting laminin stimulation to complex AChR cluster formation. We have shown the utility of this approach by demonstrating the ...

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An UNC 40 pathway directs postsynaptic membrane extension in
Caenorhabditis elegans

An UNC 40 pathway directs postsynaptic membrane extension in Caenorhabditis elegans

... gex-2 encodes the C. elegans ortholog of Rac1-associated protein 1 (also known as Sra1, p140, Pir121, Cyfip1) (Soto et al., 2002). In mammals, Sra1, together with Nck-associated protein 1 (also known as Nap1, Nckap1, ...

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The actions of L glutamate at the postsynaptic membrane of the squid giant synapse

The actions of L glutamate at the postsynaptic membrane of the squid giant synapse

... The evidence supporting L-glutamate as an excitatory transmitter at the squid giant synapse includes depression desensitization of the neurally evoked EPSP and spontaneous miniature EPSP[r] ...

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Hierarchical organization and genetically separable subfamilies of PSD95 postsynaptic supercomplexes

Hierarchical organization and genetically separable subfamilies of PSD95 postsynaptic supercomplexes

... the similarity between these proteomes might suggest that synaptic proteins associate promiscuously or by redundant mechanisms, we show using several mouse mutations that some supercomplexes have strict and selective ...

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Mechanisms of change contraction of function of the muscles in vitro at allergic

Mechanisms of change contraction of function of the muscles in vitro at allergic

... of postsynaptic membrane sensibility to CCh that is caused by increasing of non- quantal secretion of ACh in the zone of a trailer ...synaptic membrane sensibility to cholinomediate that is caused by ...

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The vertebrate neuronal gamma aminobutyric acid (GABAa) receptor and its modulation: a patch clamp study

The vertebrate neuronal gamma aminobutyric acid (GABAa) receptor and its modulation: a patch clamp study

... the postsynaptic membrane of neurones in the rat medial amygdala has been shown (Nabekura, Oomura, Minami, Mizuno and Fukado, 1986), Using intracellular recording, these workers described a brief ...

348

Zinc transporter-1 concentrates at the postsynaptic density of hippocampal synapses

Zinc transporter-1 concentrates at the postsynaptic density of hippocampal synapses

... the postsynaptic membrane, suggests that ZnT1 is an integral transmembrane protein at the PSD, which is consistent with the predicted 6 hydrophobic regions in its aminoacid sequence ...

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Stimulation induces gradual increases in the thickness and curvature of postsynaptic density of hippocampal CA1 neurons in slice cultures

Stimulation induces gradual increases in the thickness and curvature of postsynaptic density of hippocampal CA1 neurons in slice cultures

... The postsynaptic density (PSD) appears as dark ma- terial ~ 30 nm thick under the postsynaptic membrane in glutamatergic excitatory synapses of mammalian central nervous system by electron microscopy ...

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Markedly enhanced susceptibility to experimental autoimmune myasthenia gravis in the absence of decay accelerating factor protection

Markedly enhanced susceptibility to experimental autoimmune myasthenia gravis in the absence of decay accelerating factor protection

... A hallmark of human MG is the propensity for involvement of the extraocular muscles (34). In the mouse, gene expression profiling by DNA microarray has shown that Daf1 gene expression is five- to seven- fold lower in ...

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Short Communication: Do Presynaptic Muscarinic Receptors Regulate Acetylcholine Release in the Central Nervous System of the Cockroach Periplaneta Americana?

Short Communication: Do Presynaptic Muscarinic Receptors Regulate Acetylcholine Release in the Central Nervous System of the Cockroach Periplaneta Americana?

... the same site, iii The stabilities of the postsynaptic membrane resistance and resting potential, and especially the apparent stability of the CCh-induced potential, argue in favour of a[r] ...

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ELECTROPHYSIOLOGICAL EVIDENCE FOR THE MODULATION OF ACETYLCHOLINE RELEASE BY ENDOGENOUS ACETYLCHOLINE IN THE COCKROACH CENTRAL NERVOUS SYSTEM

ELECTROPHYSIOLOGICAL EVIDENCE FOR THE MODULATION OF ACETYLCHOLINE RELEASE BY ENDOGENOUS ACETYLCHOLINE IN THE COCKROACH CENTRAL NERVOUS SYSTEM

... of postsynaptic ACh receptors or a shift in the membrane ...the postsynaptic membrane potential, on the direct postsynaptic response evoked by ACh or on the postsynaptic ...

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Postsynaptic densities fragment into subcomplexes upon sonication

Postsynaptic densities fragment into subcomplexes upon sonication

... PSD is a protein complex lining the intracellular side of the postsynaptic membrane in excitatory synapses. The com- plex is disk-shaped, with average areas ranging from 0.04 to 2.4 μm 2 for different types ...

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Combined pre- and postsynaptic action of IgG antibodies in Miller Fisher syndrome

Combined pre- and postsynaptic action of IgG antibodies in Miller Fisher syndrome

... and postsynaptic analysis, endplate currents were recorded by a perfused macro-patch clamp ...electrode. Postsynaptic nicotinic acetylcholine receptor channels were investigated by an outside-out patch ...

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Pre- and postsynaptic effects of brimonidine on isolated rabbit iris dilator muscles

Pre- and postsynaptic effects of brimonidine on isolated rabbit iris dilator muscles

... These results taken together suggest that brimonidine in physiological concentrations mainly activates presynaptic α 2 -adrenoceptors and causes a small amount of pupil miosis without affecting postsynaptic α 1 ...

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Postsynaptic actions of excitatory amino acids investigated with flash photolysis

Postsynaptic actions of excitatory amino acids investigated with flash photolysis

... As e a rly a s 1963 it was show n th a t of a la rg e num ber of d ic a r boxy lie amino a c id s te s te d on sp in a l cord n e u ro n e s (C u rtis an d W atkins, 1963) th e s y n th e tic an alo g u e of a s p a rta ...

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Target recognition at the tips of postsynaptic filopodia: accumulation and function of Capricious

Target recognition at the tips of postsynaptic filopodia: accumulation and function of Capricious

... and postsynaptic muscles might occur at the tips of myopodia rather than at the muscle fiber ...and postsynaptic cells occurs and how these initial contacts are stabilized to form the synaptic sites have ...

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The different actions of chloride and potassium on postsynaptic inhibition of an isolated neurone

The different actions of chloride and potassium on postsynaptic inhibition of an isolated neurone

... To decide whether part of the inhibitory current might also be carried by potassium ions, the conductance changes of the inhibitory subsynaptic membrane were determined in solutions of d[r] ...

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Activation of a peptidergic synapse locally modulates postsynaptic calcium influx

Activation of a peptidergic synapse locally modulates postsynaptic calcium influx

... VD4 stimulation modulates postsynaptic calcium influx To determine whether VD4 stimulation also reduced the calcium transient in neurites of PI, pairs of VD4 and PI neurones were plated [r] ...

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Modulation of synaptic transmission and excitation contraction coupling in the opener muscle of the crayfish, Astacus leptodactylus, by 5 hydroxytryptamine and octopamine

Modulation of synaptic transmission and excitation contraction coupling in the opener muscle of the crayfish, Astacus leptodactylus, by 5 hydroxytryptamine and octopamine

... We address ourselves to the effects on membrane potential, membrane resistance, amplitude and time course of excitatory postsynaptic potential EPSP and excitatory postsynaptic current EP[r] ...

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Role of nucleus accumbens glutamatergic plasticity in drug addiction

Role of nucleus accumbens glutamatergic plasticity in drug addiction

... decreases postsynaptic depolarization during ...blocks postsynaptic glutamatergic receptors NMDA and GRM5, reducing depolarization in the course of ...

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