potassium channels
Hypoxic pulmonary vasoconstriction: role of voltage-gated potassium channels
... of potassium channels is a physiologic mecha- nism for reversing hypoxia-induced membrane depolariza- tion, and thereby reversing depolarization-induced ...Synthetic potassium channel openers have ...
9
Investigating Potassium Channels in Budding Yeast: A Genetic Sandbox
... for potassium uptake through two high-efficiency channels, Trk1 and Trk2 (Figure ...for potassium influx (Gaber et ...all potassium influx, but it is not essen- ...for potassium and far ...
14
Lactate activates ATP sensitive potassium channels in guinea pig ventricular myocytes
... the channels occurs and the much higher levels of ATP maintained during myocardial ...ATP-sensitive potassium channels in adult guinea pig ventricular myocytes using the whole-cell patch-clamp ...
7
Eag and HERG potassium channels as novel therapeutic targets in cancer
... voltage-gated potassium channels, comprising of four identical a subunits each consisting of six mem- brane spanning domains (S1-S6) with cytoplasmic amino (N) and carboxy (C) ...Eag channels is well ...
9
The role of voltage-gated potassium channels in the regulation of mouse uterine contractility
... We demonstrate the expression in mouse myometrium of a number of α subunit proteins belonging to the Kv family of potassium channels. While our preparations are highly enriched for uterine smooth muscle, we ...
12
Activation of potassium channels contributes to hypoxic injury in proximal tubules
... cell potassium during renal ischemia are poorly ...that potassium channels are activated as an early response to hypoxia and contribute to potassium loss independent from an inhibition of ...
7
Expression of ATP-sensitive potassium channels in human pregnant myometrium
... the most abundant potassium channels and likely contri- butes to the resting membrane potential in smooth mus- cle tissues [6]. The channel comprises heteromultimers of an inwardly rectifying K + channel ...
7
ATP-sensitive Potassium Channels and L-type Calcium Channels are Involved in Morphine-induced Hyperalgesia after Nociceptive Sensitization in Mice
... calcium channels (Ca2+ channels) and ATP-sensitive potassium channels (K+ channels) in hyperalgesia induced by morphine in dia- betic ...
8
Prognostic significance of the TREK-1 K2P potassium channels in prostate cancer
... many potassium channels blockers that may result in severe adverse effects such as cardiac arrhythmias, K 2p blockade has not been found to cause these side ...
9
Inwardly rectifying potassium channels influence Drosophila wing morphogenesis by regulating Dpp release
... Irk channels can be heteromeric, made up of subunits encoded by different genes (Bichet et ...Irk channels, but not other potassium channels, we expressed a dominant-negative Irk subunit, ...
13
The pharmacology of calcium and ATP-dependent potassium channels in erythrocytes and in smooth skeletal muscle
... Potassium channels are a diverse class of membrane proteins found in virtually all cells. The first part of this study concerns the pharmacology of the calcium activated potassium channel found in ...
215
The Blocking Activity of Different Toxins against Potassium Channels Kv3.4 in RLE Cells
... affect potassium channels are used in the treatment of hypertension, cardiac arrhythmias, type II diabetes mellitus and male pattern of baldness, and also they are under investigation for new applications ...
6
Functional cell biology and molecular pharmacology of ATP sensitive potassium channels
... Potassium channels are a diverse group of ion channels, which have a crucial role in the control of cell ...intracellular potassium ion (K+) concentration that is twenty five times higher than ...
125
Protein expression of G-protein inwardly rectifying potassium channels (GIRK) in breast cancer cells
... rectifying potassium channels (GIRK) in both the heart and brain [8], but no effects of ethanol on GIRK channels in breast cancer have been reported in the litera- ...
7
Clofilium inhibits Slick and Slack potassium channels
... Slack channels could be used therapeutically as drug ...these channels will result in important tools for the study of the physiological significance of Slick and Slack channels in different tissues ...
6
Expression of voltage dependent potassium channels in first trimester human placentae
... Expression of voltage-dependent potassium channels in first trimester human placentae.. Cartwright 4, Fiona Broughton.[r] ...
12
Role of ATP-sensitive potassium channels on hypoxic pulmonary vasoconstriction in endotoxemia
... gated potassium channels have been shown to be one of the key regulators of HPV [5], but in candidates like ...KATP channels has been shown to increase pulmonary artery resistance ...
10
The influence of protons and zinc ions on the steady-state inactivation of Kv1.3 potassium channels
... Kv1.3 channels can be activated under physiological conditions only within a “window” of membrane potentials where they are open and not ...The channels can be activated under physiological conditions only ...
11
The pharmacology of three inwardly rectifying potassium Channels in neonatal rat cardiac myocytes.
... Action potential duration and activation of the ATP-sensitive K+ current in isolated guinea pig ventricular myocytes. Strong Voltage-Dependent Inward Rectification[r] ...
220
Characterization of single non inactivating potassium channels in primary neuronal cultures of Drosophila
... Permeability and gating properties of single, non-inactivating K + channel currents in neurons of eag, a mutant which has defects in the delayed rectifier K + channel, were indistinguish[r] ...
12