Potential for multiple mechanisms
Leveraging Multiple Mechanisms for Information Propagation.
... Aggregate population behavioral types could be leveraged to better understand the potential for influencing individuals that belong to certain communities, or for characterizing these various groups in terms of ...
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Multiple Mechanisms of Immune Suppression by B Lymphocytes
... Although B cells have previously ex- pressed IL-10 under various conditions, the importance of B cell–derived IL-10 in immunosuppression was not defini- tively demonstrated until the last decade (1,18,29,30). In 2002, ...
15
Multiple Mechanisms of Immune Suppression by B Lymphocytes
... Although B cells have previously ex- pressed IL-10 under various conditions, the importance of B cell–derived IL-10 in immunosuppression was not defini- tively demonstrated until the last decade (1,18,29,30). In 2002, ...
15
Multiple mechanisms of MYCN dysregulation in Wilms tumour
... all potential mechanisms of dysregulation have the same functional effect on downstream pathways or tumour ...for multiple copies of a variant that confers a growth ...
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Microcirculatory alterations: potential mechanisms and implications for therapy
... Multiple mechanisms may contribute to these alterations, including endothelial dysfunction, impaired inter-cell communication, altered glycocalyx, adhesion and rolling of white blood cells and platelets, ...
8
Neonatal diabetes mellitus: a disease linked to multiple mechanisms
... V. Treatment A. Therapeutic consequences in the case of potassium channel mutation The K ATP channels have a central role in cell response to metabolic changes in many organs and especially in pan- creatic insulin ...
11
Potential treatment mechanisms in a mindfulness-based intervention for people with progressive multiple sclerosis
... Several potential confounders were included as covariates to strengthen the validity of this assumption: baseline level of the GHQ total score, age, sex, and MS type, plus the baseline levels of pain and ...
47
Mechanisms of myelin degradation in multiple sclerosis
... the mechanisms of demyelination that are occuring, in MS and the animal model EAE, previous studies have employed in vitro cultures of developing CNS tissue where often serum or cells from one species are added to ...
225
Overcoming multiple drug resistance mechanisms in medulloblastoma
... Our results showed that vardenafil enhances etoposide cytotoxicity in ABCB1-expressing MB cell lines. The activ- ity of vardenafil in each of our assays was equivalent to that of the non-specific ABCB1 inhibitor ...
14
Overcoming multiple drug resistance mechanisms in medulloblastoma
... children and infants with pulmonary arterial hypertension and portal hypertension with minimal adverse effects at concentrations above those indicated in our study [66,67]. It has been previously shown that vardenafil ...
14
Pathophysiological and cognitive mechanisms of fatigue in multiple sclerosis
... Recently developed computational methods might enhance the use of EEG data for differential diagnosis of fatigue and treatment prediction. For example, biophysical models of EEG data have shown promising potential ...
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HDAC4 in ischemic stroke: mechanisms and therapeutic potential
... Growing evidence indicates that HDAC4 may contribute to neurogenesis via regulating the expression and func- tion of multiple molecules. First, HDAC4 regulates the activity and expression of cAMP response ...
9
Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.
... 12 Standard quality-control measures were applied to the GWAS 45 . Specifically, individuals with low SNP call rate (<95%) as well as individuals evaluated to be of non-European ancestry (using the HapMap version 2 ...
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Casein kinase 1α: biological mechanisms and theranostic potential
... 73. Peterson TR, Laplante M, Thoreen CC, Sancak Y, Kang SA, Kuehl WM, et al. DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival. Cell. 2009;137:873 – 86. ...
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Sox7 in vascular development: review, insights and potential mechanisms
... molecular mechanisms of Sox7 action have largely remained ...propose mechanisms connecting all of these important developmental pathways through Sox7, in a way not previously postulated in the developing ...
9
Aspirin use and potential mechanisms for colorectal cancer prevention
... However, almost any drug given to humans can have multiple effects depending on the dosage and duration of therapy. Since the introduction of widespread NSAID therapy in humans, several reports have indicated a ...
6
Neurodegeneration in multiple sclerosis involves multiple pathogenic mechanisms
... in multiple sclerosis (MS) was viewed as a secondary process resulting from inflammatory ...pathological mechanisms independent of myelin loss that contribute to the axonal loss and neurodegeneration ...
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The diverse mechanisms and anticancer potential of naphthoquinones
... Conclusions Naphthoquinones act as anticancer agents through a variety of mechanisms involved in all types of cancer. Some of the most important explored so far and which have been extendedly reported in the ...
20
Potential hormone mechanisms of bariatric surgery
... Effect of Roux-en-Y gastric bypass on the distribution and hormone expression of small-intestinal enteroendocrine cells in obese patients with type 2 diabetes. Numerous alterations in th[r] ...
16
Bacterial ghosts as adjuvants: mechanisms and potential
... 6 Conclusion and future prospectus BG are potential envelope structures which not only act as potent candidate vaccines but also have efficient adju- vant and delivery system properties. The future of BG seems to ...
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