Potential genetic, environmental, physiological, and pathological
Physiological and pathological implications of 5-hydroxymethylcytosine in diseases
... Demethylation via 5hmC conversion in alimentary system malignancies Alimentary system consists of mouth, esophagus, stomach, intestine and their accessory organs including pancreas, liver and cholecyst. Rich blood ...
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The pathological roles of environmental and redox stresses in cardiovascular diseases
... and environmental chemicals could elevate the risk of cardiovascular ...by environmental oxidants or increased endogenous production of ROS [62, ...of environmental cardiology, we need to elucidate ...
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Pathological and physiological functions of presenilins
... PSAP, a PDZ-like protein, QM/Jif-1, a negative regulator of c-Jun; DRAL, an LIM-domain protein; proliferation- associated gene product, a protein of the thioredoxin per- oxidase family; β-secretase, BACE1; PAMP and PARL, ...
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Pathological conditions re-shape physiological Tregs into pathological Tregs
... winged-helix family of transcription factors, which acts as a “master regulator” (for multiple pathways) for the development and suppressive function of Tregs [11-13]. The significance of FOXP3 gene was identified by its ...
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A physiological framework to explain genetic and environmental regulation of tillering in sorghum
... and environmental effects on tillering are generally associated with differences in the onset of tillering, and thus with the frequency of appearance of early tillers (Kim et ...to potential leaf area ...
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Role of laminins in physiological and pathological angiogenesis
... In cancer, a peculiar mechanism of tumour cell dissemination was described where tumour cells migrated along the external surface of vessels; this mechanism is called extravascular migratory metastasis (Lugassy and ...
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Identifying genetic variants and environmental factors influencing multiple sclerosis pathological processes
... The first study that provided evidence supporting the potential role of HHV-6 in MS was performed by Challoner and colleagues 59 . The authors found the presence of anti- HHV-6 monoclonal antibodies specific to ...
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Involvement of microRNAs in physiological and pathological processes in the lung
... diverse physiological processes ranging from developmental timing to apoptosis, miRNAs have a strong potential to regulate fundamental biological processes also in the lung ...in physiological and ...
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An investigation of the physiological and pathological role of uncoupling proteins
... Liability statement By using a Digitised Thesis, I accept that Trinity College Dublin bears no legal responsibility for the accuracy, legality or comprehensiveness of materials contained within the thesis, and that ...
252
The Pathological and Physiological Roles of IL-6 Amplifier Activation
... the physiological relevance of the gateway to the central nervous ...a potential molecular mechanism for the relationship between neural activation and the development of inflammatory diseases, which could ...
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Histone deacetylases (HDAC) in physiological and pathological bone remodelling
... HDAC 3 (Class I) has been shown to interact with Runx2, repressing the activation of the osteocalcin promoter. HDACi (TSA) and shRNA to HDAC3 were able to reverse this repression [16]. In these studies, suppression of ...
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Drebrin From Structure and Function to Physiological and Pathological Roles
... 4 which is expressed in the nervous tissue. During these years, we purified chicken and rat drebrins, raised polyclonal and monoclonal antibodies, and cloned DBN1 cDNAs. Consequently, we have identified major isoforms of ...
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Physiological and Pathological Roles for MicroRNAs: Implications for Immunity Complications
... Psoriasis is a typical, chronic, relapsing/remitting and sustained inflammatory immune-mediated skin disease which is marked by red, scaly squares, papules and plaques which frequently itch [65]. The causes of psoriasis ...
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The Physiological and Pathological Role of Mitochondrial Calcium in the Diabetic Heart
... membrane potential between ...under physiological Ca concentrations and that the reduction in MCU activity is redox ...the potential mechanisms underlying supply-demand mismatching in diabetic ...
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Physiological processes associated with genetic progress in yield potential of wheat (Triticum aestivum L.)
... Table A20 Effect of the interaction between tiller inhibition (TIN) gene and seed density on plant height and rachis length at GS61 in some OH lines during 08/09, 09/1 0 seasons at CIMMY[r] ...
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Crk and CrkL adaptor proteins: networks for physiological and pathological signaling
... The above studies suggest that Crk may have a central role in cell motility and metastasis in highly aggressive motile cancer cells. There are a plethora of studies showing that p130Cas-HEF and the FAK-Src circuitry is ...
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Genomic and proteomic characterization of physiological and pathological angiogenesis in the human eye
... 59 6. DISCUSSION The importance of the LESCs in corneal biology and regeneration is well known, the absence or removal of which can cause defective corneal regeneration 47,48 . In humans, several diseases are known with ...
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Genetic and physiological analysis of juvenility in plants
... multiple environmental and endogenous pathways promote and enable floral ...effect. Genetic and molecular approaches have iden- tified genes that are responsible for the photoperiod ...
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Nutritional and Methodological Perspectives of Zinc Ions and Complexes - Physiological and Pathological States
... 3.1.1. Modulating factors in health Several factors have been described as potential modulators of micronutrients needs. In the case of zinc, it is known that physical activity improve the daily recommendations ...
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Cellular oxygen sensing need in CNS function: physiological and pathological implications
... Brain oxygen sensing need Neuron cell function and viability, and thus structural and functional integrity of the brain, rely heavily on a constant oxygen and glucose supply. A large proportion of the neuronal ATP ...
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