precision medicine
Precision medicine at the crossroads
... the Precision Medicine Initiative (recently rebranded the All of Us Research Program), which was launched with great fanfare by an administration no longer in office [11], are likely to end up under-funded, ...
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Charting Ecosystems of Complex Phenomena: The Precision Medicine Case
... The diversity and complexity of this new reality bring a myriad of aspects that should be considered in an integrated way to have an all-encompassing understanding of PM. Nevertheless, scientific works have basically ...
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Precision Medicine: the importance of correctly matching the tool to the task
... translational medicine project in collaboration with Karolinska Institute, Jamie moved to Sweden to oversee the completion of this muscle genomics project and then ran a group in the Centre for Genomics and ...
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Emergency medical genomes: a breakthrough application of precision medicine
... genomic medicine, even in these ...consequent precision medicine care plans, and a lack of test ...genomic medicine lacks a breakthrough ...dynamic precision medicine decision ...
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Two predictive precision medicine tools for hepatocellular carcinoma
... predictive precision medicine tools for hepatocellular ...predictive precision medicine tools are helpful for predicting the individual mortality risk probability and improving the ...
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Reconciling evidence-based medicine and precision medicine in the era of big data: challenges and opportunities
... in precision medicine — a data-driven approach centering on the ...of precision medicine poses numerous challenges. Foremost, precision medicine needs to be contrasted with the ...
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Veterinary Oncology:Biology, Big Data and Precision Medicine
... Pang, L & Argyle, D 2016, 'Veterinary Oncology: Biology, Big Data and Precision Medicine' Veterinary Journal, vol.. DOI: 10.1016/j.tvjl.2016.03.009.[r] ...
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ApreciseKUre: an approach of Precision Medicine in a Rare Disease
... Precision medicine (PM) is an emerging approach for dis- ease prevention, diagnosis and treatment that takes into ac- count individual variability in genes, environment, metabolomics, proteomics and ...
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Smart polymers for cell therapy and precision medicine
... Soft materials have been developed very rapidly in the biomedical field over the past 10 years because of advances in medical devices, cell therapy, and 3D printing for precision medicine. Smart polymers ...
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Male Infertility, Precision Medicine and Systems Proteomics
... Precision medicine: With the launch of the human genome project in the late 1980s, the researchers hoped that a change would occur in healthcare, given the genetic differences of each person with regard to ...
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Precision medicine requires precision in clinical interpretation and reporting with NAVIFY Mutation Profiler
... Since cancer is not the result of a single gene mutation, but rather of multiple gene mutations, the very real possibility that patient management options may vary for patients based on combinations of variants is being ...
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The Limits of Responsible Innovation: Exploring Care, Vulnerability and Precision Medicine
... targeted medicine in fi elds such as oncology where some cancer patients, for example breast cancer patients with HER2 positive or oestrogen receptor positive cancers are offered targeted treatments as part of ...
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Precision medicine approaches for the management of Ewing sarcoma: current perspectives
... Abstract: Advancements in molecular and genetic techniques have significantly furthered our biological understanding of Ewing sarcoma (ES). ES is typified by a driving TET–ETS fusion with an otherwise relatively quiet ...
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<p>Towards Precision Medicine in Systemic Lupus Erythematosus</p>
... to precision targeting do exist with conventional ...that precision medicine ...the precision approaches available for the treatment of rheumatoid arthritis where currently fi ve- ...
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<p>Challenges and Future Prospects of Precision Medicine in Psychiatry</p>
... Abstract: Precision medicine is increasingly recognized as a promising approach to improve disease treatment, taking into consideration the individual clinical and biological characteristics shared by speci ...
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The limits of responsible innovation: Exploring care, vulnerability and precision medicine
... arise. Precision medicine involves innovations in the role of patients, publics, sci- entists and healthcare professionals, as well as in the stewardship of ...treatment. Precision medicine ...
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The limits of responsible innovation: Exploring care, vulnerability and precision medicine
... the precision medicine era, but a narrower focus on precision medicine as a form of technological innovation which in turn places emphasis on responsibilities for risk mitigation via ...
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Precision medicine becomes reality—tumor type-agnostic therapy
... Precision medicine just witnessed two breakthroughs in oncology in 2017. Pembrolizumab (Keytruda), Merck’s anti- programmed cell death-1 (PD-1) monoclonal antibody (mAb), received accelerated approval in ...
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An integrated clinical and genomic information system for cancer precision medicine
... Recently several groups reported implementation of CGISs which addressed computational and clinical is- sues involved. PathOS is a web-based CGIS incorporat- ing variant filtering, curation and reporting, but it was ...
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Big data hurdles in precision medicine and precision public health
... that precision medicine will provide tailored health care to patients and will yield lower rates of associated adverse ...Although precision medicine aims at preven- tion, diagnosis and ...
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