Predicted transmembrane interactions between Protein E and MraY
Genetic Analysis of MraY Inhibition by the ϕX174 Protein E
... ABSTRACT Protein E, the lysis protein of bacteriophage fX174, is a specific inhibitor of MraY, the phospho- MurNAc-pentapeptide translocase that catalyzes the synthesis of lipid I in the ...
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Inhibition of phospho MurNAc pentapeptide translocase (MraY) by nucleoside natural product antibiotics, bacteriophage <phi>X174 lysis protein E, and cationic antibacterial peptides
... translocase MraY and related phospho-GlcNAc transferases WecA and TagO, and insight into the inhibition and catalytic mechanism of this class of integral membrane proteins from the structure of Aquifex aeolicus ...
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Interaction of translocase MraY with the antibacterial E protein from bacteriophage ΦX174
... the predicted transmembrane interactions between protein E and MraY and shown that favourable interactions can be formed between Phe288 and the RWXXW motif ...
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Genetic Interactions Between UNC-17/VAChT and a Novel Transmembrane Protein in Caenorhabditis elegans
... Acknowledgments We are grateful to Yuji Kohara for the yk1353e09 cDNA, Kiely Grundahl for technical assistance, Jim Henthorn for assistance with confocal imaging, Bob Barstead for sharing the PCR-based point-mutant ...
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Transmembrane and cytoplasmic domains in integrin activation and protein-protein interactions (Review)
... However, the F2F3 talin fragment was successfully crystallized on its own, and the particular arrange- ment of molecules within the crystal suggested that a chimeric talin-integrin molecule could be designed so as to ...
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Exploration of the omics evidence landscape: adding qualitative labels to predicted protein protein interactions
... refer e e d re sear chdeposited research interacti o ns inf o rmation Several metabolic pathways are completely retrieved, such as the arginine and the threonine biosynthesis pathways, which are connected ...
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Homomeric interactions between transmembrane proteins of Moloney murine leukemia virus.
... was predicted that the leucine zipper-like region was involved in the oligomerization of envelope proteins (10, 14), recent stud- ies point to a role of the motif in the fusion of viral and cellular ...(F) ...
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Role of Predicted Transmembrane Domains for Type III Translocation, Pore Formation, and Signaling by the Yersinia pseudotuberculosis YopB Protein
... the transmembrane segment is derived from a relatively untilted 20-residue portion of the hydrophobic sequence and that the rest of the hydrophobic sequence protrudes from the ...the protein. For Tar and ...
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The Unique Transmembrane Hairpin of Flavivirus Fusion Protein E Is Essential for Membrane Fusion
... the interactions of the TM1 and TM2 helices within the anchor and with other parts of E are not known for the postfusion conformation of ...Therefore, interactions not only between the two ...
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Transmembrane domain interactions in carnitine palmitoyltransferase I
... the protein drive the oligomerisation and kinetics of the full-length ...contact between TM helices and suggest that oligomer formation is favoured by the relative positioning of helix-helix interaction ...
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Functional Domains in the Retroviral Transmembrane Protein
... occur between monomers of the envelope protein ...distinct predicted features of MoMuLV TM, in order to analyze functional interactions between dif- ferent regions of the TM ...their ...
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The Structure of a Transmembrane Protein Sorting Complex
... resident protein (Wang et ...physical interactions of components of the ...exposed protein-protein interaction face and may mediate its interaction with the Bag-6 ...interplay between ...
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Sdmg1 is a conserved transmembrane protein associated with germ cell sex determination and germline soma interactions in mice
... differences between germ cell development in male and female ...differences between membrane-trafficking pathways in male and female embryonic supporting cells could generate sex-specific activities from ...
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Protein-protein interactions
... of protein antigen interfaces provided the basis for the prediction of structural epitopes on the surface of lysozyme and the p subunit of human chorionic ...observed between predicted epitopes and ...
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Mutagenesis of Dengue Virus Protein NS2A Revealed a Novel Domain Responsible for Virus-Induced Cytopathic Effect and Interactions between NS2A and NS2B Transmembrane Segments
... lecular interactions between pTMS7 and pTMS1, pTMS2, pTMS3, or pTMS4 of NS2A were responsible for the ...Intermolecular interactions between pTMSs of NS2A and pTMS4 of NS2B were also ...
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Modularity analysis based on predicted protein-protein interactions provides new insights into pathogenicity and cellular process of Escherichia coli O157:H7
... the predicted O157 ...the predicted modules can provide possible candidates for biological pathway extension and clues for discovering new modes of cross-talk between ...
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Interactions between the Transmembrane Segments of the Alphavirus E1 and E2 Proteins Play a Role in Virus Budding and Fusion
... pH-induced trimerization. Transfected and [ 35 S]methionine-labeled BHK-21 cells (10-min pulse starting at 6.5 h posttransfection; 1.5-h chase) grown on 24-well plates were washed once and then incubated either in 20 mM ...
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Understanding communication signals during mycobacterial latency through predicted genome-wide protein interactions and boolean modeling
... The network based approach supplemented with Boolean modeling in elucidating crosstalk between the upregulated and downregulated genes leads us to propose a fascinating hypothesis of the latency process. We ...
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These receptor complexes are commonly formed between a member of the Frizzled family of seven-pass transmembrane proteins and a co-receptor, which is usually a singlepass transmembrane protein
... To identify proteins that might function redundantly with Ror and thus explain the lack of a mutant phenotype, candidate genes were checked for genetic interactions with Ror 4 . However, with the exception of ...
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Predicted protein-protein interactions in the moss Physcomitrella patens: a new bioinformatic resource.
... first predicted protein-protein interactome for a bryophyte based on the interolog method contains 67,740 unique interactions from 5,695 different Physcomitrella patens ...conserved ...
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