prevention trials
Risk Factors and Primary Prevention Trials for Type 1 Diabetes
... Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease resulting in the designated immune destruction of insulin producing β-cells, usually diagnosed in youth, and associated with important psychological, ...
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“Spatial heterogeneity of environmental risk in randomized prevention trials: consequences and modeling”
... The aim of this study was to highlight the impact of the spatial heterogeneity of non-measured environmental risk on the results of prevention trials by using simulated data in different scenarios. We have ...
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A rapid review indicated higher recruitment rates in treatment trials than in prevention trials
... in prevention trials is different to that in treat- ment ...treatment trials is often driven by a desire for symptom relief, whereas if there is any clinical reward for an essentially healthy ...
8
Involvement of Fathers in Pediatric Obesity Treatment and Prevention Trials: A Systematic Review
... methodological gaps in the literature stemming from the relative absence of fathers in pediatric obesity treatment and prevention studies that included parent involvement. Targeted recruitment strategies are ...
13
Future possibilities in the prevention of breast cancer: Breast cancer prevention trials
... the prevention trials and to attempt to explain the difference in results between the NSABP study [3 • ] and the European trials (IBIS and [5 • –7 • ]) that have been reported to ...European ...
6
For debate: substituting placebo controls in long-term Alzheimer's prevention trials
... ondary prevention of dementia due to AD could be the place for the proposed PGSA? No doubt some of the earlier (phase 1 and phase 2) trials, which are often per- formed on healthy subjects and subsequently ...
11
PubMedCentral-PMC5048498.pdf
... controlled prevention trials in CHR cases have ...small trials with antipsychotic drugs do not support a prophylactic effect on conversion risk beyond the period of active treatment (39, ...
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The effectiveness of shoe insoles for the prevention and treatment of low back pain: a systematic review and meta analysis of randomised controlled trials
... controlled trials or crossover trials that compared orthoses or insoles with no treatment or placebo treatment were included in this ...the prevention or treatment of non-specific ...Treatment ...
8
Effect of aspirin on disability free survival in the healthy elderly
... persistent physical disability 20%. When all the events (not just the first event to occur) were taken into account, the rates of dementia were similar in the two groups and there was no evi- dence of an effect of ...
10
Aspirin for prophylactic use in the primary prevention of cardiovascular disease and cancer : a systematic review and overview of reviews
... primary prevention of cancer or CVD are relatively modest, remain statistically uncertain, and are an order of magnitude less than that observed in secondary prevention for ...primary prevention ...
273
Using neighborhood level census data to predict diabetes progression in patients with laboratory defined prediabetes
... traditional predictors of diabetes progression and found that education, income, and receipt of SNAP benefits were all significant predictors of progression to diabetes within 36 months. This finding suggests that ...
6
Clinical aspects and socio-economic implications of implantable cardioverter defibrillator treatment
... More recently, efforts have been made to construct a risk model on an ICD treated population in a real world population outside the setting of a clinical trial. Initially, risk models were constructed to identify ...
181
Oral chlorhexidine in the prevention of ventilator-associated pneumonia in critically ill adults in the ICU: A systematic review
... Eight studies published in English were included in this systematic review and contributed to its overall completeness. Chlorhexidine proved to be beneficial in the prevention of VAP, with 2% chlorhexidine ...
8
Management of postoperative nausea and vomiting: focus on palonosetron
... antagonist licensed and the only drug of its class approved for prophylaxis against both acute and delayed chemotherapy- induced nausea and vomiting (CINV). Its unique properties have led to it being described as the fi ...
14
A double masked placebo controlled trial of azithromycin to prevent child mortality in Burkina Faso, West Africa: Community Health with Azithromycin Trial (CHAT) study protocol
... trolled trials in which we evaluate the efficacy of tar- geted azithromycin distribution in both the presence and the absence of biannual mass azithromycin distri- bution using a hierarchical factorial design ...
9
Probiotics: Not Just for Treatment Anymore
... as prevention and the publication of positive study results, it seems that probiotics some day could play a significant role in the control of many common childhood conditions that have socioeconomic im- ...as ...
6
The effects of dietary intervention on HIV dyslipidaemia : a systematic review and meta analysis
... primary prevention, from 47 RCTs (16,511 subjects), a mean dose 3?25 g/d and duration 24 weeks, reduced triglyceride by 20?34 mmol/l (95%CI 20?41 to 20?27) from mean baseline 2?44 ...in trials, as ...
13
Preventative Strategies in the Management of ROP: A Review of Literature
... clinical trials of Vitamin E supplementation in premature infants to prevent ROP ...these trials from the late 1980s found that the incidence of severe ROP was not significantly de- creased; however they ...
7
Essentials of Nursing Care in Randomized Controlled Trials of Nurse Led Interventions in Somatic Care: A Systematic Review
... Forty-seven percent (n = 26) of the RCTs in somatic care presented a theoretical standpoint related to the nurse- led intervention (Table 2) and most prominent were international evidence-based guidelines (n = 9). As ...
17
Searching MEDLINE for Randomized Clinical Trials Involving Care of the Newborn
... Therefore, the sensitivity, specificity, and positive predictive value of two MED- LINE search strategies designed to detect randomized clinical trials for prevention and treatment of ne[r] ...
6