Primary adrenal insufficiency
Sphingosine 1 phosphate lyase mutations cause primary adrenal insufficiency and steroid resistant nephrotic syndrome
... Primary adrenal insufficiency is life threatening and can present alone or in combination with other ...a primary adrenal insufficiency syndrome and steroid-resistant nephrotic ...
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Hyponatremia in Primary Adrenal Insufficiency: An Often Overlooked Cause of Decreased Sodium Levels
... with primary adrenal insufficiency is mainly attributed to increased secretion of antidiuretic hormone (ADH), which in turn results in water retention and dilutional decrease of serum sodium ...with ...
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Congenital primary adrenal insufficiency and selective aldosterone defects presenting as salt-wasting in infancy: a single center 10-year experience
... FGD, also known as hereditary unresponsiveness to ACTH, is characterized by lack of response to ACTH leading to adrenal insufficiency with subnormal gluco- corticoid levels and remarkably elevated plasma ...
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Exploration of knowledge and understanding in patients with primary adrenal insufficiency: a mixed methods study
... an adrenal crisis and hospital admis- sion [6, ...that adrenal crisis still occurs even in patients with chronic adrenal insufficiency who have been educated ...
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Acquired modification of sphingosine-1-phosphate lyase activity is not related to adrenal insufficiency
... S1P lyase mediates the final step of the sphingolipid metabolism which is the irreversible breakdown of S1P to ethanolamine phosphate and hexadecenal [4]. Inhib- ition of S1P lyase activity will lead to accumulation of ...
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An unusual cause of adrenal insufficiency and bilateral adrenal masses
... Primary adrenal insufficiency secondary to syphilis is extremely rare, with only five cases being reported in the ...of adrenal insufficiency as a manifestation of Treponema pallidum ...
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POEMS syndrome: a rare cause of adrenal insufficiency in a young male
... or primary, the latter being more common and developing in the majority of patients after receiving melphalan treatment ...one primary, abnormal glucose metabolism in 24%, high IGF-1 in ...and ...
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Clinical characteristics of adrenal crisis in adult population with and without predisposing chronic adrenal insufficiency: a retrospective cohort study
... (primary adrenal insufficiency [PAI]: 119, secondary adrenal insuf- ficiency [SAI]: 66) ...were primary AI, a concomitant disease, age at diagnosis, being female, and diabetes ...
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Adrenal Insufficiency: Still a Cause of Morbidity and Death in Childhood
... ACTH cannot be used as a criterion for glucocorticoid dose adjustment in primary adrenal insufficiency. At- tempts at achieving ACTH levels within the reference range leads to chronic ...
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Mutations in sphingosine 1 phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency
... rapidly progressed to end-stage renal disease (ESRD). Histologi- cally, FSGS was the main finding, but diffuse mesangial sclerosis (DMS) was found in cases with congenital NS (Tables 1 and 2 and Supplemental Figure 3). ...
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Prophylaxis of Early Adrenal Insufficiency to Prevent Bronchopulmonary Dysplasia: A Multicenter Trial
... although lower cortisol values in the first week of life correlated with a longer duration of oxygen therapy, by the second week the reverse was true: higher cortisol values correlated with longer duration of oxygen ...
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Peri portal lymphedema in association with an acute adrenal insufficiency: case report
... Moreover, adrenal insufficiency has been shown to manifest, in a single case report, as an acute mesenteric is- chemia [4], intestinal pseudo-obstruction and long-term intermittent hyponatremia ...
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Evidence of Early Adrenal Insufficiency in Babies Who Develop Bronchopulmonary Dysplasia
... We chose to evaluate response to ACTH stimula- tion at the end of the first week of life, because limited data from term newborns showed that they had a normal response to ACTH immediate[r] ...
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Acute adrenal insufficiency following arthroplasty: a case report and review of the literature
... subacute adrenal haemorrhage show high attenuation (50–90 HU) at unenhanced computed tomography (CT), without enhancement following intravenous (IV) ...confirm adrenal haemorrhage. Like CT, the appearance ...
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Early onset obesity and adrenal insufficiency associated with a homozygous POMC mutation
... with adrenal insufficiency usually present with weight loss, fatigue, hypoglycemia, severe infections and ...with adrenal insuf- ficiency due to isolated ACTH deficiency, based on her clinical ...
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A descriptive study of adrenal crises in adults with adrenal insufficiency: increased risk with age and in those with bacterial infections
... Adrenal steroid replacement therapy consists of a glucocorticoid (GC) (cortisone acetate or hydrocorti- sone) or a longer acting GC (prednisolone/prednisone or dexamethasone) and mineralocorticoid replacement ...
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Studies on Auditory Thresholds in Normal Man and in Patients with Adrenal Cortical Insufficiency: The Role of Adrenal Cortical Steroids
... with adrenal cortical insufficiency (four with Addison's disease and four with panhypopituitarism) and compared to those in normal ...In adrenal cortical insufficiency (ACI) the auditory ...
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The importance of adrenal hypoandrogenism in infertile women with low functional ovarian reserve: a case study of associated adrenal insufficiency
... the adrenal cortex can be subjects of autoimmune attacks, sharing risks and manifesting different combinations of ...of adrenal autoimmunity in presence of autoimmune attacks against the other two ...
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Myotonic dystrophy type 1 with diabetes mellitus, mixed hypogonadism and adrenal insufficiency
... Hypogonadism is associated with increase in fat mass and loss of muscle mass and strength. Hypogonadotropic hypogonadism (secondary hypogonadism) is treated by hCG therapy or selective estrogen receptor modulators ...
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Adrenal insufficiency in a child following unilateral excision of a dual-hormone secreting phaeochromocytoma
... An urgent CT head did not demonstrate any intracranial abnormalities or features of raised intracranial pressure. A full septic screen, including lumbar puncture, was unremarkable with normal inflammatory markers and ...
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