Primary & Subgroup Analyses 1186 patients in study
Exacerbation heterogeneity in COPD: subgroup analyses from the FLAME study
... COPD patients, with some at risk owing to airflow limitation and/or prior exacerbation history and some at risk because of ...that patients receive optimal treatment at the very earliest opportunity to ...
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Single-inhaler triple therapy in symptomatic COPD patients: FULFIL subgroup analyses.
... This study has previously been presented in abstract form at the 2017 ERS International Congress (Milan, Italy) [13] and the 2017 British Thoracic Society Winter Meeting (London, UK) ...the study, and ...
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Model-Based Recursive Partitioning for Subgroup Analyses
... The ALS Functional Rating Scale (ALSFRS [36]), is a widely used instrument for evaluating the functional status of patients with ALS even though the uni-dimensionality of the score seems questionable [37]. It is ...
20
Interpretation of subgroup analyses in systematic reviews: A tutorial
... individual study results to obtain a pooled treatment effect ...of patients or trials, by performing subgroup ...a subgroup analysis, all participant data included in the meta-analysis is ...
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A meta-epidemiological study of subgroup analyses in cochrane systematic reviews of atrial fibrillation
... [2]. Subgroup analyses may be conducted in SRs by dividing data across studies into groups based on participant or study characteristics in order to compare them or to partition out sources of ...
14
A Critical Review of Graphics for Subgroup Analyses in Clinical Trials
... each subgroup is further divided into smaller subgroups of sample sizes N 21 , using again sliding window with an overlap of N 22 ...that patients in both treatment and control arms are ...formed ...
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Darunavir/cobicistat/emtricitabine/tenofovir alafenamide in treatment-experienced, virologically suppressed patients with HIV-1: subgroup analyses of the phase 3 EMERALD study
... for patients who rebounded and those with prior VF ...of patients initi- ated lipid-lowering therapy during the study, with no significant differences between treatment ...of patients with ≥ 1 ...
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Characteristics of GPs responding to an educational intervention to minimise inappropriate prescriptions: subgroup analyses of the Rx-PAD study
... from subgroup analyses are usually unreliable because of reduction in statisti- cal power, which may lead to incorrect ...this study managed to control for multiple testing, hence reducing false ...
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The effects of timing of prophylaxis, type of anesthesia, and use of mechanical methods on outcome in major orthopedic surgery - subgroup analyses from 17,701 patients in the XAMOS study
... to patients receiving epidural anesthesia with indwelling ....17,000 patients in daily ...in patients who received neuraxial anesthe- sia compared with patients who received general anesthesia ...
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Subgroup analyses in confirmatory clinical trials: time to be specific about their purposes
... positive subgroup finding can be considered confirma- ...These study de- signs are to date almost exclusively applied to new on- cology drugs, where both a biomarker-positive and a biomarker-negative ...
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Loss of tumor suppressors KAI1 and p27 identifies a unique subgroup of primary melanoma patients with poor prognosis
... present study, we performed statistical analysis on a patient cohort with large sample size, and identified the metastasis-like subgroup of primary melanomas in order to develop a clinically ...
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An observational study of duloxetine versus SSRI monotherapy in Japanese patients with major depressive disorder: subgroup analyses of treatment effectiveness for pain, depressive symptoms, and quality of life
... Methods study design and patients This was a prospective, observational, 12-week study assess- ing treatment outcomes in patients with MDD and PPS who received duloxetine or one of the ...
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Methods for estimating subgroup effects in cost-effectiveness analyses that use observational data.
... all patients benefit from it ...this study excluded the cost of rhDNase and only assessed respiratory tract infection–related health ...The study suggested that rhDNase (administered once or twice ...
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Efficacy and safety of indacaterol/glycopyrronium in Japanese patients with COPD: a subgroup analysis from the SHINE study
... the primary variable, with the appropriate baseline measurement included as a ...of patients who achieved a clini- cally important improvement in the SGRQ and TDI focal score were analyzed using logistic ...
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VRK2 identifies a subgroup of primary high-grade astrocytomas with a better prognosis
... those patients lost during follow-up were ...[36]. Patients were ranked according to their risk score and divided into two groups using the median risk score as ...statistical analyses were performed ...
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<p>Pooled analysis of tanezumab efficacy and safety with subgroup analyses of phase III clinical trials in patients with osteoarthritis pain of the knee or hip</p>
... real-world study of patients with knee OA, more than half (54%) of patients reported inadequate pain relief, significant functional loss, and lower quality of ...of patients with new ...
21
Phenotypic and molecular analyses of primary lateral sclerosis
... all patients to test for the presence of known disease- causing mutations associated with other neurodegener- ative ...recent study indicates that this particular heterozygos- ity can be pathogenic for HSP ...
8
Safety and efficacy of Pazopanib in advanced soft tissue sarcoma: PALETTE (EORTC 62072) subgroup analyses.
... diagnosed patients being older than 65 years ...elderly patients versus younger patients [6, 7], poor prognosis in older patients might also relate to undertreatment based on misconceptions of ...
7
Catheter related Candidabloodstream infection in intensive care unit patients: a subgroup analysis of the China SCAN study
... in hospital-based candidemia studies from western countries [5-8]. The CRCBSI and NCRCBSI groups were compared in order to identify risk factors for CRCBSI. Results showed that the two groups were similar in disease, ...
9
Effect of denosumab on bone mineral density in Japanese women with osteopenia treated with aromatase inhibitors for breast cancer: subgroup analyses of a Phase II study
... prospective study, which demonstrated that denosumab, a fully human monoclonal antibody against receptor activator of nuclear-factor kappa-B ligand, increased BMD in the lumbar spine and femoral neck in ...
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