prognostic biomarker
Use of the prognostic biomarker suPAR in the emergency department improves risk stratification but has no effect on mortality: a cluster-randomized clinical trial (TRIAGE III)
... shown, that adding a prognostic biomarker would strengthen risk stratification and lead to improved patient outcome and flow in the ED [5, 6, 11]. In addition, early risk stratification has previously been ...
10
IGFBP6 is a novel nasopharyngeal carcinoma prognostic biomarker
... Though IGFBP6 appears to act as an inhibitory agent in various tumors, some studies found that it stimulated growth in a smaller number of tumors [12]. In ovarian cancer cell lines, differential effects of IGFBP6 on ...
11
Original Article Serum expression of miRNA-103, a potential diagnostic and prognostic biomarker for colorectal cancer
... the presence of distant metastasis or lymph node metastasis. From Figure 3, the results of Kaplan-Meier analysis with the log-rank test revealed that high serum expression of miR- 103 was significantly correlated with a ...
7
MicroRNA 9 expression is a prognostic biomarker in patients with osteosarcoma
... chance of survival or chemotherapy response, especially early in treatment, preferably even before surgery. Previ- ous studies have found that miR-9 is downregulated in several cancers, including ovarian cancer, colon ...
5
<p>hsa_circRNA_101237: A Novel Diagnostic and Prognostic Biomarker and Potential Therapeutic Target for Multiple Myeloma</p>
... found that circRNAs adsorb speci fi c miRNAs to in fl uence the expression of mRNA, thereby performing their biological functions. 31,32 Our bioinformatic analysis identi fi ed 11 miRNAs and 10 candidate mRNAs which might ...
10
X-linked inhibitor of apoptosis positive nuclear labeling: a new independent prognostic biomarker of breast invasive ductal carcinoma
... Smac[26]. Our data indicated not only positive ratio but also immunoscore of XIAP were more higher than Smac in breast IDC, and semi-quantitation analysis of western blot detection proved it too. But it just could be ...
9
WNT6 is a novel oncogenic prognostic biomarker in human glioblastoma
... a biomarker for tumor recurrence, which is of paramount importance to the clinical management of GBM as these patients recur almost universally after ...novel biomarker of GBM prognosis, as patients with ...
19
MicroRNA dysregulation as a prognostic biomarker in colorectal cancer
... the prognostic potential of miRNAs in ...promising prognostic marker, yet fur- ther prospective validation studies are required before it can go into clinical ...potential prognostic ...
18
MiR 221, a potential prognostic biomarker for recurrence in papillary thyroid cancer
... In conclusion, this study identified miR-221 as a signifi- cant independent predictor for PTC recurrence. However, our study also had some limitations. First, a long-term follow-up in the current study and larger cohorts ...
6
Original Article Overexpression of oncoprotein ecotropic viral integration site 1 is an independent prognostic biomarker of gastric cancer
... All data were analyzed with soft- ware SPSS 17.0 (IBM cooperation, Chicago, USA). The correlation be- tween EVI1 expression and clinico- pathological factors was analyzed by Chi-square test. Kaplan-Meier meth- od was ...
7
Investigation of p16INK4a as a prognostic biomarker in oral epithelial dysplasia
... current), alcohol (None, <21 units, >21 units) morphology (white patch, speckled red/white, red patch, ulcer and mass), site (tongue, floor of mouth, palate, buccal, retromolar) and histological grade (mild, ...
18
RRM2 is a potential prognostic biomarker with functional significance in glioma
... therefore involved in many kinds of cancers including colorectal cancer, non-small cell lung cancer (NSCLC), breast cancer, bladder cancer, ovarian cancer, pancreatic cancer, head and neck cancer[12-16]. RRM2 is also ...
11
Copeptin, a novel prognostic biomarker in ventilator associated pneumonia
... VAP and sepsis impose stress on patients, potentially promot- ing cardiovascular instability and an elevated demand for vaso- pressin and glucocorticoid secretion. Our data showed that copeptin levels increased ...
9
Serum miR-26a as a diagnostic and prognostic biomarker in cholangiocarcinoma
... Based on these previous results, we focused our study on the efficacy of serum miR-26a as a diagnostic biomarker in patients with CCA in the following experiments. So we generated ROC curves to assess the ...
10
MAP17 (PDZKIP1) as a novel prognostic biomarker for laryngeal cancer
... can benefit from therapies such as cisplatin or radiotherapy that increase oxidative stress and could sensitize them to cell death. In this setting, our analysis in laryngeal cancer showed a significant relationship ...
12
CDH22 hypermethylation is an independent prognostic biomarker in breast cancer
... Importantly, CDH22 hypermethylation was signifi- cantly associated with shorter PFS and OS in our large series of BC patients. Accordingly, CDH22 de- regulation was associated with clinical outcome in other cancer types: ...
8
SNW1 is a prognostic biomarker in prostate cancer
... The prognostic effect of SNW1 expression was stron- ger in ERG negative than in ERG positive cancers but also retained in the latter ...strong prognostic role of SNW1 expression in ERG negative ...different ...
8
Prognostic nutritional index as a prognostic biomarker for survival in digestive system carcinomas
... independent prognostic factor for patients’ survival: shorter OS and DFS, as well as the appearance of post-operative complications of digestive system cancers, especially in gastric carcinomas, colorectal ...
11
Blood eosinophil count as a prognostic biomarker in COPD
... impact of persistent blood eosinophilia on COPD in the KOLD cohort. However, a contradicting report suggested that, regardless of the eosinophilic cutoff, patients with eosinophilic COPD exhibited no specific ...
8
suPAR as a prognostic biomarker in sepsis
... In a small series of patients with CCHF, serum suPAR levels were related to renal and hepatic function and were of prognostic value [22]. No analysis for confounding fac- tors was made by the authors of this ...
9