progressive supranuclear palsy (PSP)
Multireceptor fingerprints in progressive supranuclear palsy
... Fig. 1 Receptor fingerprints of progressive supranuclear palsy (PSP)-related receptor density alterations in the caudate nucleus (a – c) and area 24 ′ (d – f). Polar plots showing the mean relative ...
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Tau burden and the functional connectome in Alzheimer's disease and progressive supranuclear palsy
... and progressive supranuclear palsy (PSP) represent neurodegenerative tauopathies with predominantly cortical versus subcortical disease ...a progressive weakening of the connectivity of these ...
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Pyramidal system involvement in progressive supranuclear palsy – a clinicopathological correlation
... PSP: progressive supranuclear palsy; PSP-C: PSP with predominant cerebellar ataxia; PSP-CBS: PSP-corticobasal syndrome; PSP- F: PSP with early frontal lobe cognitive or behavioral presentations; PSP- ...
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Concomitant progressive supranuclear palsy and chronic traumatic encephalopathy in a boxer
... PSP: Progressive supranuclear palsy; QSBB: Queen Square Brain Bank for Neurological Disorders; RS: Richardson ’ s syndrome; SCA: Spinocerebellar ataxia; SN: Substantia nigra; STN: Subthalamic ...
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Exercise and progressive supranuclear palsy : the need for explicit exercise reporting
... Progressive Supranuclear Palsy (PSP) is comparatively rare. Nevertheless, it is the most frequent form of atypical Parkinsonism [1–3]. The prevalence estimates range from 5 to 6 per 100,000 [4] to 18 ...
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Performance on the PD test battery by relatives of patients with progressive supranuclear palsy
... If we assume an autosomal recessive mode of transmission, then 25% or approximately 6 of the 23 FDR tested in the current study would be expected to carry the putative gene or be at risk. Alterna- tively, an autosomal ...
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Clinical Profile of Cognitive Decline in Patients with Parkinson's Disease, Progressive Supranuclear Palsy, and Multiple System Atrophy.
... PD, progressive supranuclear palsy (PSP), and multiple system atrophy (MSA) groups and compare them using Mini–Mental State Examination (MMSE), frontal assessment battery (FAB), and verbal fluency ...
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Loss of insight in frontotemporal dementia, corticobasal degeneration and progressive supranuclear palsy
... and progressive supranuclear palsy (PSP) (Kitagaki et ...a progressive non-fluent aphasia, indicating CBD is a cognitive disorder as well as a motor disorder, making this condition difficult ...
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Neuroimaging-pathological correlations of [18F]THK5351 PET in progressive supranuclear palsy
... Recent positron emission tomography (PET) studies have demonstrated the accumulation of tau PET tracer in the affected region of progressive supranuclear palsy (PSP) cases. To confirm the binding ...
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Disrupted Resting State Functional Connectivity in Progressive Supranuclear Palsy
... FIG 2. Differences between 19 patients with progressive supranuclear palsy and 12 healthy sub- jects in functional connectivity obtained from 5 seeds (2-sample t test, P ⬍ .05, corrected for ...
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An autopsy-confirmed case of progressive supranuclear palsy with predominant postural instability
... and supranuclear gaze palsy represent the key symptoms of Richardson ’ s syndrome, the most frequent clinical manifestation of progressive supranuclear palsy ...gaze palsy ...
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Effects of Cystamine, a Transglutaminase Inhibitor, in a Mouse Model of Progressive Supranuclear Palsy
... disease, Progressive Supranuclear Palsy (PSP), and corticobasal degeneration are characterized by neuropathological changes including the aggregation of microtubule-associated protein tau (Lewis et ...
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The midbrain to pons ratioA simple and specific MRI sign of progressive supranuclear palsy
... gressive supranuclear palsy; PSPRS 5 Progressive Supranuclear Palsy Rating Scale; UMSARS 5 Unified Multiple System Atrophy Rating Scale; UPDRS 5 Unified Parkinson’s Disease Rating ...
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Trial of Zolpidem, Eszopiclone, and Other GABA Agonists in a Patient with Progressive Supranuclear Palsy
... Progressive supranuclear palsy (PSP) is a progressive, debilitating neurodegenerative disease of the Parkinson-plus family of syndromes. Unfortunately, there are no pharmacologic treatments ...
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A Fully Automated, Atlas Based Approach for Superior Cerebellar Peduncle Evaluation in Progressive Supranuclear Palsy Phenotypes
... confirmed the presence of a more severe involvement of white matter rather than cortical gray matter in PSP pathology. In par- ticular, imaging alterations have been found in the superior cere- bellar peduncles (SCPs), ...
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Communication impairments in people with progressive supranuclear palsy: a tutorial
... The evidence appears to be conflicting, but cognitive impairments and executive dysfunction are frequently present in patients with PSP. Brown et al. (2010, p. 2389) concluded that “there is little reliable or consistent ...
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Critical appraisal of the role of davunetide in the treatment of progressive supranuclear palsy
... Abstract: Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease characterized by the accumulation of tau protein aggregates in the basal ganglia, brainstem and cerebral cortex ...
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A case of atypical progressive supranuclear palsy
... Progressive supranuclear palsy (PSP) is a neurodegenerative extrapyramidal syndrome, characterized by motor symptoms, such as postural instability, rigidity, akinesia, and behavioral and cognitive ...
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Characterization of tau oligomeric seeds in progressive supranuclear palsy
... Background: Progressive supranuclear palsy (PSP) is a neurodegenerative tauopathy which is primarily defined by the deposition of tau into globose-type neurofibrillary tangles ...
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Spatial patterns of the tau pathology in progressive supranuclear palsy
... Objective Progressive supranuclear palsy (PSP) is characterized neuropathologically by neuronal loss, gliosis, and the presence of tau-immunoreactive neuronal and glial cell inclusions affecting ...
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