Proliferation and invasion
<p>TRIB3 suppresses proliferation and invasion and promotes apoptosis of endometrial cancer cells by regulating the AKT signaling pathway</p>
... cell proliferation ability, and flow cytometry was performed to assess the apoptosis of EC ...and invasion of EC cells were detected by transwell assay, and the levels of MMP-2 and MMP-9 were measured by ...
11
<p>GAS2 Promotes Cell Proliferation and Invasion and Suppresses Apoptosis in Pediatric T-Cell Acute Lymphoblastic Leukemia and Activates Wnt/β-Catenin Pathway</p>
... Results: GAS2 was highly expressed in Jurkat and CCRF-CEM cells. GAS2 could promote cell proliferation and invasion, and inhibit apoptosis of Jurkat and CCRF-CEM cells. GAS2 also promoted cell cycle changes ...
10
Original Article Activation of NPY1R increases the proliferation and invasion of human uterine leiomyosarcoma cells
... and invasion of human uterine leiomyosar- coma cells, and NPY1R antagonist markedly decreased the proliferation and invasion, espe- cially in presence of NPY1R ...
10
Knockdown of IFI27 inhibits cell proliferation and invasion in oral squamous cell carcinoma
... cell proliferation; Annexin V-PI staining flow cytometry was used to detect the effect of IFI27 downregulation on apoptosis of cancer ...cell invasion was detected using Transwell ...
7
Crosstalk between EGFR and integrin affects invasion and proliferation of gastric cancer cell line, SGC7901
... there are also crosstalks between EGFR and integrin path- ways in human gastric adenocarcinoma. Once EGF binds its ligand, EGFR, activated signals include not only ERK and PKB, but also FAK, paxillin, and p130cas, which ...
7
SDF 1/CXCR7 axis regulates the proliferation, invasion, adhesion, and angiogenesis of gastric cancer cells
... of invasion, adhesion, proteolysis, and ...cancer invasion and ...cell invasion is ...enhanced proliferation and invasion, and silencing of CXCR7 significantly inhibited the ...
10
Upregulation of FAM83D affects the proliferation and invasion of hepatocellular carcinoma
... tumor’s proliferation and invasion, while also increasing its level of apoptosis, have been major areas of focus in our ...the proliferation, migration, and invasiveness of Huh7 and HepG2 ...
16
CDKL1 promotes tumor proliferation and invasion in colorectal cancer
... Materials and methods: Expression of CDKL1 in colorectal cancer tissues and cell lines was measured by immunohistochemistry and Western blot, respectively. To investigate the role of CDKL1 in colorectal cancer, ...
12
HOXB5 Promotes the Proliferation and Invasion of Breast Cancer Cells
... empty vector as well as parent MCF7 cells (Fig. 4C). In addition, the cells with high HOXB5 expression facil- itated anchorage-independent cell growth and showed significant increases in both number and size of colonies ...
11
XB130 promotes proliferation and invasion of gastric cancer cells
... The proliferation, migration, and invasion of SGC7901 and MNK45 gastric adenocarcinoma cell lines were all significantly inhibited by knockdown of XB130 using small hairpin ...
11
<p>Paeonol Inhibits Cell Proliferation, Migration and Invasion and Induces Apoptosis in Hepatocellular Carcinoma by Regulating miR-21-5p/KLF6 Axis</p>
... The regulatory effects of miR-21-5p on tumor develop- ment have been extensively identi fi ed in many cancers. For instance, miR-21-5p enhanced cell proliferation, migration and invasion in NSCLC via ...
13
TRIM52 up-regulation in hepatocellular carcinoma cells promotes proliferation, migration and invasion through the ubiquitination of PPM1A
... the proliferation of MHCC-97L cells at 24, 48 and 72 h compared with Vector or pLVX-Puro-TRIM52 transfection, ...the proliferation of MHCC-97L cells at 24, 48 and 72 h compared with only pLVX-Puro-TRIM52 ...
13
<p>CircLARP4 Suppresses Cell Proliferation, Invasion and Glycolysis and Promotes Apoptosis in Non-Small Cell Lung Cancer by Targeting miR-135b</p>
... cell proliferation versus pcDNA-transfected cells (Figure ...Transwell invasion assay uncovered that cell invasive ability in A549 and H1299 cells was signi fi cantly dampened in response to circLARP4 ...
12
The effects of lncRNA MALAT1 on proliferation, invasion and migration in colorectal cancer through regulating SOX9
... growth, invasion and migration of colorectal cancer cells through down-regulating miR-145 The OD value of si-MALAT1 cells was the least in the two types of cell ...The proliferation ability of si-MALAT1 + ...
15
Original Article Retinol-binding protein 4 regulates the biological functions and molecular mechanisms of JEG-3 cells
... the proliferation and invasion of JEG-3 ...the invasion and proliferation of JEG-3 cells and increased MMP2 and MMP9 in JEG-3 ...trophoblast invasion and migration and represents a ...
8
Original Article miR-761 inhibits human osteosarcoma progression by targeting CXCR1
... Abstract: microRNAs (miRs) are endogenous noncoding RNAs that participate in a variety of cellular processes by regulating multiple targets to promote or inhibit cell behaviors. Emerging evidence suggests that miR-761 ...
8
The roles of Wnt/β-catenin signaling pathway related lncRNAs in cancer
... tumor proliferation, migration, and invasion in glioma via the Wnt/β-catenin signal ...the proliferation and migration of glioma cells can be increased by targeting SOX7 to activate the Wnt/β-catenin ...
9
miR-10b suppresses cell invasion and metastasis through targeting HOXA3 regulated by FAK/YAP signaling pathway in clear-cell renal cell carcinoma
... suppresses proliferation and invasion capabilities in ccRCC cells To further explore the mechanisms underlying the inhibitory effects of miR-10b on tumor invasion and metastasis, we performed ...
10
PIM1 regulates glycolysis and promotes tumor progression in hepatocellular carcinoma
... of PIM1 protein in human HCCs in a cohort of clinical samples. Furthermore, PIM1 was more frequently expressed in extra-hepatic HCC metastases than the corresponding primary HCCs. By Western blotting, we observed ...
13
<p>FOXK1, Regulated by miR-365-3p, Promotes Cell Growth and EMT Indicates Unfavorable Prognosis in Breast Cancer</p>
... Transwell invasion assay demonstrated that up-regulation of miR- 365-3p reversed the effects of FOXK1 on proliferation and invasion in MDA-MB-231 cells, and inhibition of miR-365-3p reversed the ...
12