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Proliferation and survival

MicroRNA 155 is essential for the optimal proliferation and survival of plasmablast B cells

MicroRNA 155 is essential for the optimal proliferation and survival of plasmablast B cells

... the survival and proliferation of plasmablasts in a B-cell – intrinsic manner, by tracking antigen-speci fi c B cells in vivo since the onset of antigen ...the survival and pro- liferation of ...

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Characterization of Drosophila mini-me, a Gene Required for Cell Proliferation and Survival

Characterization of Drosophila mini-me, a Gene Required for Cell Proliferation and Survival

... In the developing Drosophila eye, the morphogenetic furrow is a developmental organizing center for patterning and cell proliferation. The furrow acts both to limit eye size and to coordinate the number of cells ...

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Growth factor regulation of proliferation and survival of multipotential stromal cells

Growth factor regulation of proliferation and survival of multipotential stromal cells

... Multipotential stromal cells (MSCs) have been touted to provide an alternative to conservative procedures of therapy, be it heart transplants, bone reconstruction, kidney grafts, or skin, neuronal and cartilage repair. A ...

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The Sonic hedgehog pathway independently controls the patterning, proliferation and survival of neuroepithelial cells by regulating Gli activity

The Sonic hedgehog pathway independently controls the patterning, proliferation and survival of neuroepithelial cells by regulating Gli activity

... cell survival and advancing the cell ...the survival of neural ...the proliferation rate of these cells being retarded to the same extent as ventral ...promote proliferation ventrally. Other ...

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Prothymosin α, a protein implicated in the proliferation and survival of lymphocytes

Prothymosin α, a protein implicated in the proliferation and survival of lymphocytes

... The loss of interaction of ProTα with its targets is observed when cell proliferation of the Jurkat cells is reduced by serum deprivation or apoptosis induced by staurosporine. These effects seem to indicate that ...

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Inhibition of human lung cancer cell proliferation and survival by wine

Inhibition of human lung cancer cell proliferation and survival by wine

... inhibited proliferation of A549 human lung adenocarcinoma ...of proliferation (Figure 1B) but its effect was not statistically different from the other red wines ...clonogenic survival assays in our ...

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Proliferation and Survival Mechanisms in Soft Tissue Sarcoma and Glioblastoma Tumors

Proliferation and Survival Mechanisms in Soft Tissue Sarcoma and Glioblastoma Tumors

... pro- proliferation signaling, the Hippo pathway is inactivated, allowing unphosphorylated YAP to translocate into the nucleus, where it binds the Tea Domain Family of transcription factors (TEAD1-4) and directs ...

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Proton-sensing GPCR-YAP Signalling Promotes Cell Proliferation and Survival

Proton-sensing GPCR-YAP Signalling Promotes Cell Proliferation and Survival

... cell survival and ...cell proliferation and ...cell survival and proliferation via binding to TEAD family transcription factors [29], was observed in the immunofluorescence assays ...

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PPP5C promotes cell proliferation and survival in human prostate cancer by regulating of the JNK and ERK1/2 phosphorylation

PPP5C promotes cell proliferation and survival in human prostate cancer by regulating of the JNK and ERK1/2 phosphorylation

... JNK, and P38 levels after PPP5C downregulation and found that the phosphorylation of ERK1/2 and JNK was significantly increased with the non-phosphorylation was fixed (Figures 6 and 7). But whether the phosphorylation or ...

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A study of schwann cell survival, proliferation and interaction with neurons

A study of schwann cell survival, proliferation and interaction with neurons

... significant differences in its morphology, antigenic phenotype, survival ability and proliferation from either neural crest cells or Schwann cells. In embryo day (E) 14 rat sciatic nerve, many tight bundles ...

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Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF

Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF

... the proliferation of newly-gen- erated hippocampal progenitors in highly-active male WT ...reduced survival of these cells reflect bona fide effects of reduced postnatal, neuronal expression of BDNF, and ...

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The regulation of cardiac cell proliferation and survival during vertebrate development

The regulation of cardiac cell proliferation and survival during vertebrate development

... cell proliferation specifically during this developmental window, with several studies demonstrating that FGFs 1, 2 and 4, which are expressed beginning at gastrulation (Hamberger-Hamilton stage 5 in chick) in the ...

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ANGIOGENESIS AND CANCER THERAPY

ANGIOGENESIS AND CANCER THERAPY

... Various studies have proved that the endothelial growth factor and their associated receptor 2 (VEGFR-2) are critical in the proliferation and survival of various cancers through the regulation of ...

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Single Cell Proliferation to Produce Monoclonal Population of Transfected Caprine Fibroblast Cell

Single Cell Proliferation to Produce Monoclonal Population of Transfected Caprine Fibroblast Cell

... its proliferation, which include methods of single cell pickup, analysis of media supplements on growth parameters and optimizing the best condition for single cell ...cell proliferation and ...

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Original Article The functional role of RNF113A in cervical carcinogenesis

Original Article The functional role of RNF113A in cervical carcinogenesis

... Abstract: RNF113A is thought to function as an E3 ligase, engaged in the regulation of the turnover and activ- ity of many target proteins. However, the fuctional role of RNF113A in cervical cancer remains unclear. In ...

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A study of Schwann cell survival, proliferation and interaction with neurons

A study of Schwann cell survival, proliferation and interaction with neurons

... Following serum exposure for 5 days the mitogenic activity of FGF-2 plus forskolin is more potent in adult Schwann cells than in neonatal cells. The experiments above [r] ...

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Hydrazinobenzoylcurcumin inhibits androgen receptor activity and growth of castration-resistant prostate cancer in mice

Hydrazinobenzoylcurcumin inhibits androgen receptor activity and growth of castration-resistant prostate cancer in mice

... There is a critical need for therapeutic agents that can target the amino-terminal domain (NTD) of androgen receptor (AR) for the treatment of castration-resistant prostate cancer (CRPC). Calmodulin (CaM) binds to the AR ...

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PubMedCentral-PMC5083215.pdf

PubMedCentral-PMC5083215.pdf

... clinical survival of ESCC ...cell proliferation and survival during development, its overexpression in squamous epithelial cells of ESCC, its amplification in a subset of ESCC, its essential role for ...

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Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer.

Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer.

... FiGURe 1 | Schematic representation of the interplay between PI3K/Akt signaling and redox stress. Activation of PI3K/Akt signaling occurs following stimulation of receptor tyrosine kinases (RTKs) or G-protein-coupled ...

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Synergy between molecular biology and imaging science toward mechanism based biomarkers associated with prostate cancer

Synergy between molecular biology and imaging science toward mechanism based biomarkers associated with prostate cancer

... A number of other signaling pathways interact with the AR signaling. For example, the epidermal growth factor receptor (EGFR) is expressed in 40% to 80% of malignant prostate cancer cells [41]. EGFR is a family of four ...

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