proliferator-activated receptor gamma
Interaction between peroxisome proliferator-activated receptor gamma polymorphism and obesity on type 2 diabetes in a Chinese Han population
... Aims: The aim of this study was to investigate the association of four single nucleotide polymorphisms (SNPs) of peroxisome proliferator-activated receptor gamma (PPARG) with type 2 di[r] ...
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Sperm metabolism in pigs: a role for peroxisome proliferator activated receptor gamma (PPARγ)
... Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear hormone receptor expressed predominantly in adipose tissue, also implicated in energy ...
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Association of peroxisome proliferator activated receptor gamma (PPARγ) polymorphism in north west Punjabi population in relation to causation of coronary artery disease
... Peroxisome proliferator activated receptor gamma (PPARγ) a member of nuclear receptor expressed at high levels in mammalian adipose tissue, contributes substantially in the regulation ...
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Peroxisome proliferator-activated receptor gamma modulation and lipogenic response in adipocytes of small-for-gestational age offspring
... peroxisome proliferator-activated receptor gamma (PPAR γ ), and increased fatty acid de novo synthesis during the nursing period, prior to onset of ...
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Knockdown of peroxisome proliferator-activated receptor gamma coactivator-1 alpha increased apoptosis of human endometrial cancer HEC-1A cells
... Peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) coactivates multiple transcription factors and regulates several metabolic ...
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PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA, AN EMERGING POTENTIAL TARGET TO COMBAT METABOLIC DISORDER
... peroxisome proliferator-activated receptor-gamma (PPAR-γ) as potential target ...nuclear receptor also discussed. Being as nuclear receptor more genomics exploitation needs to be ...
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Oleuropein as an inhibitor of peroxisome proliferator-activated receptor gamma
... (Floyd et al. 2008) and curcumin from curcuma (Ejaz et al. 2009) suppressed adipogenesis on 3T3-L1 cell line through several mechanisms including attenuation of peroxisome proliferator-activated ...
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Interaction between Calpain 5, Peroxisome proliferator-activated receptor-gamma and Peroxisome proliferator-activated receptor-delta genes: a polygenic approach to obesity
... The existence of calpain activity over NRs, could exist not only inside the mitochondria, but also in the nucleus, being a possible biological explanation for the unusual presence of proteases into the nucleus; this ...
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Peroxisome Proliferator Activated Receptor Gamma Expression in the Lung Tissue of Obese Rats
... Purpose: Obesity is a risk factor for asthma and type II diabetes. Peroxisome prolif- erator-activated receptor (PPAR)-γ has been suggested to regulate inflammatory re- sponses in diabetes and asthma. We ...
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Activation of peroxisome proliferator– activated receptor gamma induces anti-inflammatory properties in the chicken free avian respiratory macrophages
... Alveolar macrophages (AM) in mammals constitute first line of pulmonary defense where they expunge deposited foreign particles and kill pathogens that land on the vast and thin gas-blood tissue barrier [1]. Following ...
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Peroxisome Proliferator Activated Receptor-gamma P465L Point Mutation in Diabetes and Atherosclerosis
... In our experiments using the Lee double mutant mice, generated from a cross between L/+ and Apoe -/- mice, it is not possible to differentiate between the contribution of the mutant PPARγ in macrophage and foam cells ...
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Oleamide activates peroxisome proliferator-activated receptor gamma (PPARγ) in vitro
... Peroxisome proliferator-activated receptors (PPARs) are a subfamily of nuclear receptors, which function as ligand- activated transcription factors ...
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Functional Characterization of Peroxisomes and Peroxisome Proliferator Activated Receptor-Gamma in the Chicken Respiratory System
... Nitric oxide secretion has also been used as a readout system for the identification of pathogen associated molecular patterns (PAMP) with macrophage-activating activity. From the initial studies on NO biology in ...
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Genetic studies in type2 diabetes in unani concepts of temperament; association between pro12ala polymorphism of peroxisome proliferator activated receptor gamma 2 (PPAR α) of Indian populati
... The PPAR-gamma gene, which is located on chromosome 3, can induce the transcription of target genes after ligand- dependent activation or in a ligand-independent manner. Several genetic variants in the ...
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Emerging role of the peroxisome proliferator-activated receptor-gamma in hepatocellular carcinoma
... Notes: PPARγ is composed of four different domains. The N-terminal A/B domain (containing activation function 1) is responsible for ligand-independent transactivation through phosphorylation. The DNA-binding domain ...
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Modulation of Fatty Acid Oxidation and Glucose Uptake by Oxytocin in Adipocytes
... peroxisomal proliferator activated receptor gamma (PPAR γ ), glucose transporter 4 (GLUT4), and leptin mRNA levels in adipose tissues were increased in rats, indicating that OT treatment ...
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PGC-1alpha downstream transcription factors NRF-1 and TFAM are genetic modifiers of Huntington disease
... peroxisome proliferator-activated receptor gamma coac- tivator 1a (PPARGC1A) gene encoding PGC-1alpha were shown to exert modifying effects on the AO in HD, thus providing genetic evidence ...
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Post-natal induction of PGC-1α protects against severe muscle dystrophy independently of utrophin
... Transgenic overexpression in skeletal muscle of per- oxisome proliferator-activated receptor gamma coactiva- tor (PGC)-1α has also been shown to markedly improve dystrophy in mdx mice [17]. ...
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Pioglitazone and alogliptin combination therapy in type 2 diabetes: a pathophysiologically sound treatment
... some-proliferator activated receptor-gamma to augment insulin secretion, while alogliptin improves islet function by increasing insulin secretion and lowering glucagon secretion in response to ...
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Troglitazone Enhances the Apoptotic Response of DLD 1 Colon Cancer Cells to Photodynamic Therapy
... peroxisomal proliferator-activated receptor gamma (PPARγ) ligand troglitazone in combination with photodynamic therapy (PDT) enhances the apoptotic response of DLD-1 colon cancer ...
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