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Prostaglandin analogs

First-year treatment costs among new initiators of topical prostaglandin analogs

First-year treatment costs among new initiators of topical prostaglandin analogs

... that prostaglandin analogs with a greater proportion of patients remaining on monotherapy and a longer time to initiation of adjunctive agents had lower first-year direct medical costs from a third party ...

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First-year treatment costs among new initiators of topical prostaglandin analogs: pooled results

First-year treatment costs among new initiators of topical prostaglandin analogs: pooled results

... that prostaglandin analogs with a greater proportion of patients remaining on monotherapy and a longer time to initiation of adjunctive agents had lower first-year direct medical costs from a third party ...

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Intraocular pressure dynamics with prostaglandin analogs: a clinical application of water-drinking test

Intraocular pressure dynamics with prostaglandin analogs: a clinical application of water-drinking test

... with prostaglandin analogs had significantly less IOP peak and IOP fluctuation values compared to before treatment in response to the water- drinking test, that represents outflow facility ...under ...

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Adjunctive therapy patterns in glaucoma patients using prostaglandin analogs

Adjunctive therapy patterns in glaucoma patients using prostaglandin analogs

... a prostaglandin analog was ...two prostaglandin scripts, whether the same or dif- ferent medications, on the index date were excluded, as it is unclear whether these were errors or drug ...of ...

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The effect of prostaglandin analogs on the biomechanical properties and central thickness of the cornea of patients with open-angle glaucoma: a 3-year study on 108 eyes

The effect of prostaglandin analogs on the biomechanical properties and central thickness of the cornea of patients with open-angle glaucoma: a 3-year study on 108 eyes

... with prostaglandin analogs (PGAs) is the treatment of choice for millions of patients. For the past few years, the clinical gold standard for measuring IOP was Goldmann applanation tonometry (GAT). Recent ...

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Clinical utility and differential effects of prostaglandin analogs in the management of raised intraocular pressure and ocular hypertension

Clinical utility and differential effects of prostaglandin analogs in the management of raised intraocular pressure and ocular hypertension

... Abstract: Prostaglandin analogs (PGA) are powerful topical ocular hypotensive agents available for the treatment of elevated intraocular pressure ...and analogs of prostaglandin ...

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Two-year treatment patterns and costs in glaucoma patients initiating treatment with prostaglandin analogs

Two-year treatment patterns and costs in glaucoma patients initiating treatment with prostaglandin analogs

... While these studies present evidence that BAK-free travoprost provides treatment advantages within a single year of follow-up, it was useful to extend this analysis to include two years and to examine glaucoma surgical ...

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Ocular hypotensive effect and safety of travoprost 0.004%/timolol maleate 0.5% fixed combination after change of treatment regimen from ß-blockers and prostaglandin analogs

Ocular hypotensive effect and safety of travoprost 0.004%/timolol maleate 0.5% fixed combination after change of treatment regimen from ß-blockers and prostaglandin analogs

... using prostaglandin analogs and β-blockers. The prostaglandin analogs and β-blockers were discontinued, and the treatment regimen was changed to travoprost ...

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Ocular hypotensive effects of prostaglandin analogs in Japanese patients with normal-tension glaucoma: a literature review

Ocular hypotensive effects of prostaglandin analogs in Japanese patients with normal-tension glaucoma: a literature review

... Purpose: This paper aimed to evaluate the intraocular pressure (IOP)-lowering effects of prostaglandin analogs (PGAs) in Japanese patients with normal-tension glaucoma (NTG)[r] ...

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Periorbital changes associated with prostaglandin analogs in Korean patients

Periorbital changes associated with prostaglandin analogs in Korean patients

... Prostaglandin analogs (PGAs) are popular first-line drugs for glaucoma treatment for many reasons: they powerfully reduce intraocular pressure, are associated with few systemic adverse reactions, and need ...

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Effect of prostaglandin analogs on matrix metalloproteinases and tissue inhibitor of metalloproteinases in eyelid muscle specimens

Effect of prostaglandin analogs on matrix metalloproteinases and tissue inhibitor of metalloproteinases in eyelid muscle specimens

... prostamide analogs (PAs) such as latanoprost (Pharmacia, Peapack, NJ, USA), travoprost (Alcon, Fort Worth, TX, USA) and bimatoprost (Aller- gan, Irvine, CA, USA) are a first line glaucoma ...therapy. ...

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Incidence of new coding for dry eye and ocular infection in open-angle glaucoma and ocular hypertension patients treated with prostaglandin analogs: Retrospective analysis of three medical/pharmacy claims databases

Incidence of new coding for dry eye and ocular infection in open-angle glaucoma and ocular hypertension patients treated with prostaglandin analogs: Retrospective analysis of three medical/pharmacy claims databases

... All preservatives have the potential to cause corneal and conjunctival changes, including possibly dry eye. The prevalence of clinically diagnosed dry eye among glaucoma patients in general and among those treated with ...

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Bimatoprost, latanoprost, and tafluprost induce differential expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases

Bimatoprost, latanoprost, and tafluprost induce differential expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases

... Background: Differences in the increase in matrix metalloproteinase (MMP) and decrease in tissue inhibitor of metalloproteinase (TIMP) activity may contribute to the different characteristics observed clinically on ...

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Bimatoprost in the treatment of eyelash hypotrichosis

Bimatoprost in the treatment of eyelash hypotrichosis

... Bimatoprost is classified as a category C drug according to the use-in-pregnancy ratings of the FDA. Category C denotes that animal reproduction studies have shown an adverse effect on the fetus, with no adequate and ...

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Incidence of deepening of upper eyelid sulcus after topical use of tafluprost ophthalmic solution in Japanese patients

Incidence of deepening of upper eyelid sulcus after topical use of tafluprost ophthalmic solution in Japanese patients

... Compared to these results, our finding suggests that the incidence of DUES caused by topical use of tafluprost is lower than that for bimatoprost and travoprost. However, given the small sample size and short follow-up ...

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Quality of life of glaucoma patients under medical therapy with different prostaglandins

Quality of life of glaucoma patients under medical therapy with different prostaglandins

... different prostaglandin analogs (bimatoprost, latanoprost, and travoprost) through the 25-question Brazil- ian version of the National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) and see if ...

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On the frequency of Jupiter analogs

On the frequency of Jupiter analogs

... In conclusion, we have performed detailed star-by-star simu- lations on AAPS data with a time coverage of 12 years, includ- ing the effects of eccentricity, in order to make a robust estimate of the frequency of Jupiter ...

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Exogenous Cyclic AMP, Cholera Toxin, and Endotoxin Induce Expression of the Lipopolysaccharide Receptor CD14 in Murine Bone Marrow Cells: Role of Purinoreceptors

Exogenous Cyclic AMP, Cholera Toxin, and Endotoxin Induce Expression of the Lipopolysaccharide Receptor CD14 in Murine Bone Marrow Cells: Role of Purinoreceptors

... Although a number of studies were conducted to analyze LPS signaling in fully differentiated cells, little is known about the signaling pathways by which LPS induces the expression of new surface molecules or receptors ...

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Production of phenylacetyl-homoserine lactone analogs by artificial biosynthetic pathway in Escherichia coli

Production of phenylacetyl-homoserine lactone analogs by artificial biosynthetic pathway in Escherichia coli

... HSL analogs have shown significant activity against TraR, a QS receptor, in Agrobacterium tumefa- ciens and were 1–2 orders of magnitude more active than the previously reported LuxR-type protein antagonists ...

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Clinical Decision Making of Nurses Regarding Elder Abuse

Clinical Decision Making of Nurses Regarding Elder Abuse

... phosphate buffer perchloric acid pars distalis of the pituitary gland 3’5’cyclic AMP phosphodiesterase pars distalis removal pelvic ganglia prostaglandins prostaglandin E2 prostaglandin [r] ...

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