prostaglandin E2
Microglial inhibition of neuroprotection by antagonists of the EP1 prostaglandin E2 receptor
... Cyclooxygenase-2 (COX-2), the enzyme that catalyzes the rate limiting step in the synthesis of prostanoids, contrib- utes to neuronal death. Inhibitors of COX, termed non- steroidal anti-inflammatory drugs (NSAIDs) [1], ...
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Interactions among prostaglandin E2, antidiuretic hormone, and cyclic adenosine monophosphate in modulating Cl absorption in single mouse medullary thick ascending limbs of Henle
... This paper describes the inhibitory effect of prostaglandin E2 PGE2 on antidiuretic hormone ADH-stimulated net Cl- absorption and spontaneous transepithelial voltage Ve in single medulla[r] ...
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Induction of Labour - Foley's Catheter Vs Prostaglandin E2 Gel
... Vs Prostaglandin E2 Gel” is a bonafide work done by me at Institute of Obstetrics and Gynaecology and Government Hospital for Women and Children, Madras Medical College, Chennai, during July 2008 to August ...
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A Comparison of Vaginal Misoprostol and Prostaglandin E2 for Induction of Labour at Term
... Abstract: Our objective was to compare the efficacy of vaginal misoprostol and tablet PGE2 for induction of labor at term.Methods: In this RCT a total of 140 women at term gestation were given either misoprostol (50 mcg) ...
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Effect of a single intra articular injection of bupivacaine on synovial fluid prostaglandin E2 concentrations in normal canine stifles
... Abstract Objective: To identify if synovial fluid prostaglandin E2 increases in response to a single intra-articular dose of bupivacaine in the normal canine stifle.. Results: There [r] ...
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Inhibition of sodium transport by prostaglandin E2 across the isolated, perfused rabbit collecting tubule
... (b) prostaglandin E2 inhibits net sodium transport out of the lumen by inhibiting efflux while backflux is unaffected; (c) prostaglandin E2 produces this inhibition within 15 min, and the ...
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Analysis of prostaglandin E2 effect on T lymphocyte activation Abrogation of prostaglandin E2 inhibitory effect by the tumor promotor 12 0 tetradecanoyl phorbol 13 acetate
... We have investigated the inhibitory potential of prostaglandin E2 (PGE2) with respect to intracellular messengers implicated in the signaling system of T-lymphocyte activation pathway. Using the fluorescent ...
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Biphasic effects of prostaglandin E2 on the human fat cell adenylate cyclase
... of prostaglandin E2 became apparent at GTP concentrations exceeding 10(-6) ...The prostaglandin E2-induced inhibition displayed characteristic features of prostaglandin action in intact ...
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Effect of platelet activating factor and serum treated zymosan on prostaglandin E2 synthesis, arachidonic acid release, and contraction of cultured rat mesangial cells
... Effect of platelet-activating factor and serumtreated zymosan on prostaglandin E2 synthesis, arachidonic acid release, and contraction of cultured rat mesangial cells.. The interaction o[r] ...
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The role of prostaglandin E2 receptors in the pathogenesis of rheumatoid arthritis
... that prostaglandin E2 (PGE2) contributes to the patho- genesis of RA, and nonsteroidal anti-inflammatory drugs, inhibitors of the synthesis of PGE2 and other prostanoids, continue to be used in the ...
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Butyrate attenuates lipolysis in adipocytes co-cultured with macrophages through non-prostaglandin E2–mediated and prostaglandin E2–mediated pathways
... Prostaglandin E2 (PGE2), an adipocyte and macro- phage product, is known to be involved in a variety of cell signaling pathways [8 – 10]. Production of PGE2 re- quires a supply of arachidonic acid derived ...
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The Effect of Thyroid Hormone, Prostaglandin E2, and Calcium Gluconate on Orthodontic Tooth Movement and Root Resorption in Rats
... In this study, OTM occurred significantly faster in T group compared with the control group (p< 0.01) which was in agreement with the findings of Shirazi et al. [35] The reason for the increase might be the ...
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Impaired neonatal macrophage phagocytosis is not explained by overproduction of prostaglandin E2
... Examination of a receptor responsible for mediating opsonized phagocytosis showed a significant decrease in the gene expression levels of the Fcgamma receptor in young (day 7) AMs compar[r] ...
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Cryptococcus neoformans Produces Authentic Prostaglandin E2 without a Cyclooxygenase
... cryptococcal prostaglandin production was not signif- icantly inhibited by aspirin or ...decreased prostaglandin produc- tion; however, indomethacin treatment also decreased the number of viable cells in ...
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Prostaglandin E2-induced colonic secretion in patients with and without colorectal neoplasia
... Epithelial electrogenic transport is altered in histological normal appearing colonic mucosal biopsies from patients with previous or present colorectal neoplastic disease with respect to indomethacin-sensitive mechan- ...
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Effect of prostaglandin E2 injection on the structural properties of the rat patellar tendon
... In support of PGE2 ’ s positive role in stimulating tendon remodeling, recent studies have shown that inhibitors of prostaglandin pro- duction, cyclooxgenase (COX) inhibitors, can impair[r] ...
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The role of the prostaglandin E2 receptors in vulnerability of oligodendrocyte precursor cells to death
... Using this analogy as a framework for the role of COX-2 in death of oligodendrocytes (OLs), we showed that COX-2 is induced in OLs and OPCs following glu- tamate receptor (GluR) activati[r] ...
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Characterization of the Prostaglandin E2 Response to Poxvirus Infection and of a Novel Poxvirus Antiviral
... In this study, we show that infection with the poxvirus vaccine strain, modified vaccinia Ankara virus (MVA), induces robust accumulation of PGE 2 in culture supernatants of both a mo[r] ...
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Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting
... Prostaglandins are endogenous oxygenated fatty acid metabolites and play important roles in inflammation as well as in modulat- ing arterial blood pressure and renal salt excretion (1–3). The pre- dominant effects of ...
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Receptors for prostaglandin E2 that regulate cellular immune responses in the mouse
... Thus, PGE2 regulates cellular immune responses through distinct EP receptors on different immune cell populations: EP2 receptors directly inhibit T cell proliferation while EP2 and EP4 r[r] ...
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