Prostate Cancer Progression
Integrative analysis reveals disease-associated genes and biomarkers for prostate cancer progression
... for prostate cancer [64], which were derived from differential gene ...putative prostate cancer associated module biomarker performs well with respect to the known biomarkers; therefore it ...
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Triiodothyronine Attenuates Prostate Cancer Progression Mediated by β-Adrenergic Stimulation
... tumor progression, such as EPAC, eryth- roid transcription factor (GATA1) or activator-protein 1 (AP1) ...strains cancer progression mediated by β-adrenergic receptors in a model of differentiated ...
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Genetic variants in the circadian rhythm pathway as indicators of prostate cancer progression
... of prostate cancer in two meta-analyses of data from genome- wide association studies [37, ...breast cancer [43], in line with our present results in patients with pros- tate ...colorectal ...
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miR186 suppresses prostate cancer progression by targeting Twist1
... with prostate cancer progression (Figure ...of prostate cancer, and decreased miR186 expression likely contributes to prostate cancer progression and might ...
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SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression
... promoting prostate cancer ...of prostate cancer ...suppressed prostate cancer cells proliferation, migration and invasion ...in prostate cancer, and its protein and ...
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Identification of novel targets in prostate cancer progression
... of prostate cancer becomes more comprehensive, the need for more sophisticated and accurate models increases ...human prostate cancer progression more closely and by asking more dis- ...
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FGF23 promotes prostate cancer progression
... Prostate cancer is the most common cancer in US men and the second leading cause of cancer ...all prostate cancer cell lines tested and is present at increased levels in ...
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SPINK1 protein expression and prostate cancer progression
... disease progression. Prostate cancer progression was defined as (i) time to lethal prostate cancer, defined as development of distant metastases or prostate cancer ...
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AKR1C3 overexpression may serve as a promising biomarker for prostate cancer progression
... normal prostate are dependent on stromal cells se- creting EGF, fibroblast growth factor (FGF), nerve growth factor (NGF) and IGF to support their growth and dif- ferentiation ...the progression of PCa and ...
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Decreased intracellular zinc in human tumorigenic prostate epithelial cells: a possible role in prostate cancer progression
... the prostate and in the development and/or progression of prostate cancer, we investigated the effects of extracellu- lar zinc on zinc accumulation and on mRNA and protein expression of zinc ...
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Random forest-based modelling to detect biomarkers for prostate cancer progression
... late-onset prostate cancer ( n = 222) and the TCGA PRAD cohort ( n = 477) for external validation, AUCs for sensitivity analyses were ...respectively. Cancer progression-related DNA ...
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miR-539 inhibits prostate cancer progression by directly targeting SPAG5
... We also performed microarray analysis to identify whether SPAG5 was associated with PCa progression [30–33]. We identified that high SPAG5 expression was significantly associated with higher PCa grade, and higher ...
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Genes involved in prostate cancer progression determine MRI visibility
... in cancer progression can influence MRI ...metastatic prostate cancer ...human prostate cancer cell line altered cell migration and invasion in a dose-dependent manner and ...
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Heme oxygenase-1 in macrophages controls prostate cancer progression
... kill cancer cells or cells infected with virus but also generate cytokines such as interferon-γ which induces production of pro- inflammatory cytokines in the tumor ...
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Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression
... PC progression (11). Pten heterozygous mice develop prostate intraepithelial neoplasia, whereas complete loss of functional Pten leads to tumor formation ...primary prostate tumors often show loss or ...
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MET expression during prostate cancer progression
... and bone metastases. These findings are in line with previous reports showing enhanced MET expression in HRPC bone metastases [4, 14]. This over-expression of MET was not related to genetic polysomy or amplification, ...
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Overexpression of FGF9 in Prostate Epithelial Cells Augments Reactive Stroma Formation and Promotes Prostate Cancer Progression
... during progression to ...in prostate stroma, FGFR1 and FGFR3, elicit distinct signals to control tissue homeo- stasis or induce a reactive stromal response? Are there receptor-specific pathways downstream ...
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Hypoxia - an explanation of prostate cancer progression mechanisms
... in cancer progression and metastasis ...initiation, progression, tumor stemness and resistance to therapy ...tumor progression, metastasis and resistance to common ...
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EphA6 promotes angiogenesis and prostate cancer metastasis and is associated with human prostate cancer progression
... Metastasis is the primary cause of prostate cancer (CaP)-related death. We investigate the molecular, pathologic and clinical outcome associations of EphA6 expression and CaP metastasis. The expression ...
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Prognostic value of inflammation in prostate cancer progression and response to therapeutic: a critical review
... of prostate tissue from surgery or pros- tate biopsy has sustained a possible link between chronic inflammation and PC [8, ...in cancer [7, ...in prostate tissue also through oxidative stress [8, ...
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