prostate cancers
Original Article Androgen deprivation and stem cell markers in prostate cancers
... relative to intact animals (30%) by the end of the experiment (36-wks of age). In addition, a high incidence of neuroendocrine carcinoma (NEC) was only associated with castrated TRAMP mice [9]. In an effort to determine ...
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Upregulation of centromere protein F is linked to aggressive prostate cancers
... 9,000 prostate cancers by IHC revealed detectable CENPF staining in 90% of prostate cancers, including almost 40% of tumors with no more than weak ...normal prostate glands as well as ...
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Serum Fucosylated Prostate-specific Antigen (PSA) Improves the Differentiation of Aggressive from Non-aggressive Prostate Cancers
... non-aggressive prostate cancers (Pca) by non-invasive ...included. Prostate-specific antigen (PSA), tissue inhibitor of metallopeptidase 1 (TIMP1) and tissue plas- minogen activator (tPA), and their ...
10
Are Clinically Insignificant Prostate Cancers Really Insignificant among Korean Men?
... insignificant prostate cancer (IPCa) in Koreans reliably enough to recommend active ...core-extended prostate biopsies were retrospectively ...showed prostate capsule invasion and 1 in GS 7 (4+3) had ...
5
Docetaxel Treatment in PTEN- and ERG-aberrant Metastatic Prostate Cancers.
... PTEN protein expression was determined via IHC on 4-mm-thick formalin- fi xed, paraf fi n-embedded sections as previously described [11,12]. In brief, PTEN immunoreactivity was investigated using rabbit monoclonal ...
7
The genetics of neuroendocrine prostate cancers: a review of current and emerging candidates
... Epigenetic changes control chromosomal integrity, gene functions, and, ultimately, carcinogenesis. The aberrant epigenetic events in PC include DNA hypo- and hypermethylation, chromatin remodeling, altered histone ...
6
Cervical lymphadenopathy as initial presentation of genito-urinary cancer
... had prostate cancers which were suspected only on DRE (digital rectal examination) and further confirmed by TRUS (transrectal ultrasound)guided ...of prostate cancer, bilateral orchiectomy was ...
6
Original Article The oncogenic gene fusion TMPRSS2: ERG is not a diagnostic or prognostic marker for ovarian cancer
... of prostate can- cers in humans, and contributes to the transi- tion toward androgen-independent prostate cancer through disruption of androgen receptor signaling ...[4]. Prostate cancers ...
7
Expression of HER Receptor Proteins in Prostate Adenocarcinoma: A Perspective from North Central Nigeria
... in prostate cancer devel- opment has been sparingly explored and with contrasting ...with prostate cancers cases seen in Sub-Saharan Africa is yet to be ...
13
Monoclonal Antibody against CXCL1 (HL2401) as a Novel Agent in Suppressing IL6 Expression and Tumoral Growth
... and prostate cancers [15-17], we investigated how CXCL1 influences key tumor cell ...the prostate cancer cell line PC3 expressing the highest levels of CXCL1 ...
15
Mismatch repair deficiency may be common in ductal adenocarcinoma of the prostate
... Hypermutated prostate cancers have only recently been described, with initial reported incidence ranging from approximately 3% to 12% in men with metastatic castration-resistant prostate cancer ...
7
Positron Emission Tomography (PET) Imaging of Prostate Cancer with a Gastrin Releasing Peptide Receptor Antagonist - from Mice to Men
... of prostate cancer is the gastrin re- leasing peptide receptor (GRPr), a member of the bombesin receptor ...primary prostate cancers ...hyperplastic prostate tissue demonstrate no or very low ...
8
Ki-67 and outcome in clinically localised prostate cancer: analysis of conservatively treated prostate cancer patients from the Trans-Atlantic Prostate Group study
... Trans-Atlantic Prostate Group (TAPG) of clinicians and scientists from the United States and the United Kingdom have assembled the largest cohort of prostate cancers treated by conservative means ...
6
Recurrent SKIL-activating rearrangements in ETS-negative prostate cancer
... human cancers. Roughly 60% of prostate cancers harbor gene fusions that juxtapose ETS- family transcription factors with androgen regulated ...of prostate cancers. Here we report the ...
16
Overexpression of thymidylate synthase (TYMS) is associated with aggressive tumor features and early PSA recurrence in prostate cancer
... Thymidylate synthase (TYMS) plays a role in DNA synthesis and is a target for 5-fluorouracil. In this study TYMS was analyzed by immunohistochemistry on a tissue microarray containing 11,152 prostate ...
11
Combined genetic and epigenetic interferences with interferon signaling expose prostate cancer cells to viral infection
... of prostate cancer cells. To study JAK1-defective prostate tumor cells, we opted for LNCaP cells as a model system; as Rossi et ...22Rv-1 prostate cancer cell lines ...phenocopy prostate ...
20
Socioeconomic inequality of cancer mortality in the United States: a spatial data mining approach
... mon cancers in the United States, including colorectal, lung, breast, and prostate cancers, using mortality rates aggregated at the Health Service Areas (HSA) ...
12
Cancer and Germ Cells
... breast cancers, androgen receptor increase seen in prostate cancers , is an attempted, compensatory rise, to avidly bind the suddenly, significantly, agonizingly re- duced levels of endogenous ...
11
The Norwegian PMS2 founder mutation c.989-1G > T shows high penetrance of microsatellite instable cancers with normal immunohistochemistry
... The exact penetrance and expression associated with mutations in PMS2 is not known [2]. Previous reports have referred to the gene as giving an attenuated form of Lynch Syndrome, a lower risk of CRC and a later age of ...
7
The 10-Year Incidence Trend of Common Cancers at a Referral Hospital in Tehran, Iran From 2007 to 2016
... common cancers admitted to the hospital has increased over the past 10 ...and prostate cancers, but mortality rates declined during this ...common cancers increased, the highest mortality ...
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